Embedded Files
Jakub Hlávka, Ph.D. is the Director of the Health Economics, Policy and Innovation Institute (HEPII) at Masaryk University, Brno, Czech Republic, Clinical Associate Professor (Adjunct) of Population and Public Health Sciences at the University of Southern California (USC) and a Non-Resident Fellow at the Leonard D. Schaeffer Center for Health Policy & Economics, also at USC. He also serves as the Advisor for Healthcare to the President of the Czech Republic.
Dr Hlávka's interests include Alzheimer's disease and the economics of aging, innovative payment for emerging therapies, incl. cell and gene therapies in oncology, neurology and cardiovascular disease, health system reform and the study of inequality, and resilience and preparedness in both healthcare and national security.
As of 2025, he has been leading a mutliyear $6-million consortium project on population ageing based at Masaryk University. Between 2019 and 2023, he served as a research project manager of a $2.3-million NIH grant "Ensuring Access To Novel Alzheimer’s and Dementia Treatments", which resulted in more than two dozen peer-reviewed publications in leading health economics and policy journals. His research on the COVID-19 pandemic has been funded by the CDC, DHS and the Greenwall Foundation.
He has also served as a research consultant for the National Academies of Sciences, Engineering, and Medicine (NASEM) and its Committee on Improving Representation of Women and Underrepresented Minorities in Clinical Trials and Research. He is a member of the International Pharmaco-Economic Collaboration on Alzheimer’s Disease (IPECAD). In volunteer capacity, he has worked with a non-profit medical center in a low-income neighborhood of Dandora in Nairobi, Kenya.
He previously worked at the RAND Corporation on issues related to national security, defense planning, and access to health care, at Genentech on R&D pipeline and portfolio planning, consulted for the Tufts Medical Center on outcome measurement in oncology, at the Fraunhofer Society, Germany on intellectual property regulation, at RAND Europe in Cambridge on emerging technologies and defense cooperation, with the Czech Government on fight against corruption, and the Czech Ministry of Finance on capital markets regulation.
Dr. Hlávka has been named a Young Leader by Aspen Institute Central Europe, a Leader of Tomorrow by the St. Gallen Symposium, and a Global Shaper by the World Economic Forum. He holds a PhD from the Pardee RAND Graduate School, a master’s degree from Georgetown University, Edmund A. Walsh School of Foreign Service, and an undergraduate degree from the University of Economics in Prague.
Learn more about my research in applied economics, health and international affairs.
Selected impact of my work on public discourse and economic policy.
LATEST PUBLICATIONS FOR DOWNLOAD
Hlávka J. P., Kinoshita, A. T., Jeyasingh, D., Huang, C., Mirsafian, L., Jacobson, M. (2024). Emerging Alzheimer's disease treatment paradigms: A late-stage clinical trial review. Alzheimer's & Dementia: Translational Research & Clinical Interventions. Paper URL. Paper Full-Text.
Handels, R., Herring, W. L., Kamgar, F., Aye, S., Tate, A., Green, C., Hlávka, J. P. ... & Jönsson, L. (2024). IPECAD Modeling Workshop 2023 Cross-Comparison Challenge on Cost-Effectiveness Models in Alzheimer’s Disease. Value in Health. Paper URL. Paper Full-Text.
Wolfsberger, W., Chhugani, K., Shchubelka, K., Frolova, A., Salyha, Y., Zlenko, O., Hlávka J. P. ... & Oleksyk, T. K. (2023). Scientists without borders: lessons from Ukraine. GigaScience, 12, giad045. Paper URL. Paper Full-Text.
Yu, T., Jin, S., Li, C., Chambers, J. D., & Hlávka, J. P. (2023). Factors Associated with Biosimilar Exclusions and Step Therapy Restrictions Among US Commercial Health Plans. BioDrugs, 1-10. Paper URL
Walmsley, T., Rose, A., John, R., Wei, D., Hlávka, J. P., Machado, J., & Byrd, K. (2022). Macroeconomic consequences of the COVID-19 pandemic. Economic Modelling, 106147. Full-text PDF. Paper URL.
Handels, R. L., Green, C., Gustavsson, A., Herring, W. L., Winblad, B., Wimo, A., Hlávka, J. P. ... & IPECAD modeling workshop 2020 participants (2022). Cost‐effectiveness models for Alzheimer's disease and related dementias: IPECAD modeling workshop cross‐comparison challenge. Alzheimer's & Dementia. Full-text PDF. Paper URL.
Hlávka, J. P., Tysinger, B., Jeffrey, C. Y., & Lakdawalla, D. N. (2022). Access to Disease-Modifying Alzheimer’s Therapies: Addressing Possible Challenges Using Innovative Payment Models. Value in Health. Paper Full-Text
Hlávka, J. P., Lavelle, T. A., Neumann, P. J., & Lin, P. J. (2022). Addressing Challenges to Alternative Payment Models for New Alzheimer’s Disease Therapies for US Commercial Payers. PharmacoEconomics, 1-6. Paper Full-Text
Yu, J. C., Hlávka, J. P., Joe, E., Richmond, F. J., & Lakdawalla, D. N. (2022). Impact of non‐binding FDA guidances on primary endpoint selection in Alzheimer's disease trials. Alzheimer's & Dementia: Translational Research & Clinical Interventions, 8(1), e12280. Paper Full-Text
Hlávka, J. P., Kinoshita, A. T., Fang, S., & Hunt, A. (2021). Clinical Outcome Measure Crosswalks in Alzheimer’s Disease: A Systematic Review. Journal of Alzheimer's Disease, 83(2), 591-608. Full-text PDF. Paper URL.
Hlávka, J. P., Jeffrey C. Yu, Dana P. Goldman & Darius N. Lakdawalla. (March 2021). The Economics of Alternative Payment Models for Pharmaceuticals (2021), The European Journal of Health Economics. Full-text PDF. Paper URL
Shekelle, P.G., Goldman D.P., Hlávka J.P., ... (August 2020). Prospects for Future Advances in Alzheimer’s Disease. USC Schaeffer Center White Paper. Full-Text PDF. Paper URL.
Hlávka, J. P. (2020). Security, privacy, and information-sharing aspects of healthcare artificial intelligence. Artificial Intelligence in Healthcare. Academic Press (Elsevier), pp.235-270. Full-Text PDF. Book URL. Chapter link.
Hlávka, J. P., Mattke, S., & Wilks, A. (2020). The Potential Benefits of Deferred Payment for a Hypothetical Gene Therapy for Congestive Heart Failure: A Cost-Consequence Analysis. Applied Health Economics and Health Policy, 1-9. Full-Text PDF. Paper URL.
Mulligan, K., Lakdawalla, D., Neumann, P. J., Wilensky, G. R., Goldman, D. P., Katz, R. J., Hlávka, J.P. ... & Ryan, M. (2020). Health Technology Assessment For The US Healthcare System: A White Paper From the USC Schaeffer Center ‒ Aspen Institute Advisory Panel on Health Technology Assessment in the US. USC Schaeffer Center and Aspen Institute. Full-Text PDF. Paper URL.
Hlávka, J. P., Lin, P. J., & Neumann, P. J. (2019). Outcome Measures for Oncology Alternative Payment Models: Practical Considerations and Recommendations. The American Journal of Managed Care, 25(12), e403-e409. Full-Text PDF. Paper URL.
Lam, J., Hlávka, J. P., & Mattke, S. (2019). The potential emergence of disease-modifying treatments for Alzheimer disease: the role of primary care in managing the patient journey. The Journal of the American Board of Family Medicine, 32(6), 931-940. Full-Text PDF. Paper URL.
Hlavka, J. P., Soeren Mattke, and Jodi L. Liu, Assessing the Preparedness of the Health Care System Infrastructure in Six European Countries for an Alzheimer's Treatment, Santa Monica, Calif.: RAND Corporation, RR-2503-BIOG, 2018. Full-Text PDF. Paper URL.
UPDATES
December 2024: Publications for 2023 and 2024 have been added.
May 2022: The list of my current working papers has been uploaded.
March 2021: A page listing interviews and media engagement has been uploaded.
March 2021: The list of my current working papers has been uploaded.
December 2020: A number of videos from my past music performances has been added.
June 2020: My book chapter on Data security and privacy in Healthcare AI has been published.
March 2020: Thank you for supporting my Los Angeles Charity Marathon run. We raised $2,550!
Google Sites
Report abuse