Molecular basis of learning

We focus on exploring the cellular, synaptic, and molecular mechanisms underlying physiologically relevant synaptic plasticity mechanisms using a combinatorial approach including behaviour, patch-clamp synaptic electrophysiology, FRET-biosensors, and two-photon fluorescent lifetime imaging in rodent models. We are also interested in understanding how these mechanisms are altered in neurodevelopmental diseases using transgenic animal models and patient-derived neurons. (Credit: A lot of these images are collected by Anant and team in the Yasuda lab at MPFI)