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Jacob González Isa
Jacob González Isa
PhD student, University of Cambridge
PhD student, University of Cambridge
MSc in Computational Biology | BSc in Biochemistry
MSc in Computational Biology | BSc in Biochemistry
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>Experience
PhD in Plant Sciences October 2024 - Present
Department of Plant Sciences, University of Cambridge (Cambridge, UK)
- Working in the group of Genetic and Epigenetic Inheritance in Plants (Prof. Henderson) (https://www.plantsci.cam.ac.uk/research/groups/genetic-and-epigenetic-inheritance-plants)
- Work as bioinformatician (pipeline development, design of phylogenomic studies, long-read analysis, comparative genomics across species, etc.). Linux shell, SLURM, Python and R.
- Work in wet lab. Chromatin Capture Conformation techniques (Pore-C), long-read sequencing, proteomics.
MSc thesis, Research Internship January 2024 - August 2024
CBGP (Centre of Plant Biotechnology and Genomics), Madrid (Spain)
- Working in phylogenomics and comparative genomics within the research group of Jaime Huertas-Cepas (http://compgenomics.org/team/)
- Advanced bash, R and Python integrated in High Performance Computing (HPC) with SLURM.
- ETE toolkit for phylogenomic analysis.
- Poster presentation - JABI (Conference of Bioinformatics in Andalusia)
- Poster presentation - IV International CBGP Workshop "Frontiers in Plant Sciences
- MSc thesis: “Detection of metagenomic functional enzyme variants of biotechnological and ecological interest through phylogenomics” (grade: 10/10)
Erasmus+ Research Internship July 2023 - September 2023
ISTA (Institute of Science and Technology Austria), Vienna (Austria)
- Working in Prof. Friml group, international reference in the auxin signalling field (https://ist.ac.at/en/research/friml-group/)
- CRISPR/Cas9-mediated targeted mutagenesis in Marchantia polymorpha
- Cloning (Gateway, Gibson assembly, ...), Agrobacterium-mediated transformation
- Optimization of protoplast isolation of the microalga Drapalnadia
JAE Intro CSIC - Research Internship October 2022 - June 2023
IRNAS (Institute of Natural Resources and Agrobiology of Seville), Seville (Spain)
- Working in the group of Ionic and Water Regulation in plants for eight months (https://www.irnas.csic.es/regulacion-ionica-e-hidrica-en-plantas-rih/)
- Set up of plant cultures in hydroponics and soil
- DNA extraction and genotyping, RNA-seq, RT-PCR
- Plant material collection, preservation in liquid nitrogen and lyophilization
- Poster presentation - European Plant Biology Congress 2023
BSc thesis, Research Internship October 2022 - June 2023
IBVF (Institute of Plant Biochemistry and Photosynthesis), Seville (Spain)
- Working in the group of Systems Biology and Biotech in Microalgae (https://greennetwork.us.es/systems_biology_biotechnology_microalgae/)
- Microalgae culture, optimization of ChIP-seq protocol, western blotting
- Bioinformatic analysis (cistromics and transcriptomic). R, Python and bash scripting.
- BSc thesis: "Characterization of the epigenetic modification H3K27me3 in Klebsormidium nitens" (grade: 9.5/10)
Amgen Scholars Programme - Research Internship July 2022 - September 2022
Department of Plant Sciences, University of Cambridge, Cambridge (UK)
One of the most competitive Summer Research Programmes in Europe. Funded by Amgen Foundation and coordinated by Harvard University
Working in the group of Genetic and Epigenetic Inheritance in Plants (Prof. Henderson) (https://www.plantsci.cam.ac.uk/research/groups/genetic-and-epigenetic-inheritance-plants)
Sequence alignments and phylogenetic analysis
Two poster presentations - the Sainsbury laboratory summer students' session and the Amgen European Symposium
>Education
MSc in Computational Biology January 2024 - August 2024
Technical University of Madrid
BSc in Biochemistry September 2019 - July 2023
University of Seville
>Fellowships and Awards
"la Caixa" Postgraduate Scholarship
Rafael del Pino Excellence Scholarship
Extraordinary End-Of-Degree Award
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