Hi, I'm Jack Consolini.

A mechanical engineer and former collegiate athlete passionate about helping improve the health of our planet and those living on it.

I intend to use my strong research background in programming, computational modeling, and human biomechanics, to develop improved medical treatments and technology.

Currently, I am working as a Research Engineer within the MRI Laboratory at the Hospital for Special Surgery. Within the Lab, we use Magnetic Resonance (MR) image processing software to better understand the development and healing of musculoskeletal injuries.

Featured work

Investigation of direction- and age-dependent prestretch in mouse cranial dura mater

Cranial dura mater plays a key role in healthy neurocranial remodeling in response to the growing brain. To better characterize the dura's in vivo mechanics, we developed a finite element model to determine the in vivo prestretch, an otherwise unknown quality that affects the dura's ability to properly respond to strains from the growing brain. Through comparison of the ex vivo dura and in silico model's incision opening dimensions, we observed that mouse cranial dura mater prestretch is greater in the anterior-posterior direction, and differs in magnitude across developmental ages. [PDF] [Code]

Bok's equi-volume principle: translation, historical context, and a modern persepective

In efforts to better understand the convoluted geometric patterns that arise from cortex development, we translated and re-processed experimental data from a fundamental, yet previously not revisited, study. It was observed that the six cortical lamina retain their relative volume throughout curvature, known as the "equi-volume principle". This principle has been used by researchers to extract volume and thickness information from fMRI data, as well as, geometric information from our own Abaqus brain growth simulations. [PDF] [Code]

Publications

Peer-Reviewed Journal

Consolini J, Oberman AG, Sayut J, Damen FW, Goergen CJ, Ravosa MJ, Holland MA. Investigation of direction- and age-dependent prestretch in mouse cranial dura mater. Biomechanics and Modeling in Mechanobiology. 2024; Springer Link. DOI: 10.1007/s10237-023-01802-6
Consolini J, Demirci N, Fulwider A, Hustler JJ, Holland MA. Bok’s equi-volume principle: translation, historical context, and a modern perspective. Brain Multiphysics. 2022; 3:100057. DOI: 10.1016/j.brain.2022.100057
Darayi M, Hoffman ME, Sayut J, Wang S, Demirci N, Consolini J, Holland MA. Computational models of cortical folding: a review of common approaches. Journal of Biomechanics. 2021; 139:110851. DOI: 10.1016/j.jbiomech.2021.110851

Conference Poster Presentations

Consolini J, Breighner R, Gold G, Majumdar S, Potter HG, Koff MF. Texture analysis of the infrapatellar fat pad within and between collegiate basketball and swimming athletes. International Society of Magnetic Resonance in Medicine 2024. In review.
Consolini J, Holland MA. Investigation of law of volume constancy in cortical lamina. American Physical Society March Meeting 2022. DOI: https://meetings.aps.org/Meeting/MAR22/Session/N00.303
Consolini J, Saboori P. Inflating-pulsating gloves: a new treatment for infantile cystic fibrosis. International Mechanical Engineering Congress & Exposition 2019. Poster No.: IMECE2019-13327.
Saboori P, Consolini J, Schoonover ME. Neck loading model of a child in a car seat. International Mechanical Engineering Congress & Exposition 2019. Poster No.: IMECE2019-13321.