Ivermectin is an anti-parasitic drug that aims to kill, or paralyse, parasites, without causing damage to the host [1, 2]. You can find out more about how ivermectin works here.
Ivermectin can be used in animals or humans and is commonly prescribed as a liquid, tablet, or cream [3, 4, 5, 6]. You can find out more about why ivermectin would be prescribed here.
Whilst ivermectin can be used to treat lots of different infections, it can become toxic if people take too much [7, 8]. Learn more about the effects of overdose, and how doctors might treat overdose.
Ivermectin was discovered in 1974 when a bacteria found in some soil in Japan was analysed and found to be very good at killing parasites [9, 10].
Just seven years after its discovery, Ivermectin was introduced to treat animals across the world for parasitic infections [9].
Just two years after its release, ivermectin was dubbed the “wonder drug” and became the veterinary drug of choice for many parasitic infections [10].
The World Health Organisation undertook field trials of ivermectin use in humans with onchocerciasis [10].
Just 12 years after its discovery, ivermectin was authorised for human use [9, 10].
The Nobel prize for Physiology and Medicine was awarded for the discovery of Ivermectin, along with another anti-malarial drug [11].
Ivermectin continues to be used by vets and doctors to treat animals and humans with parasitic infections. You can read more about the usage of ivermectin in animals and humans here, and learn more about how it kills parasites here.
More recently, ivermectin has gained attention for its potential use to treat COVID-19 [12]. You can learn more about ivermectin as a potential drug to treat COVID-19 here.
It is debated as to whether resistance against ivermectin is developing [10, 13]. As such, future treatments for parasitic infections may still need to be found.
More recently, the safety profile of Ivermectin has been questioned. Further research in vitro questions how safe ivermectin truly is, especially for human use [14, 15]. You can learn more about the need for a review for the safety of ivermectin in human use here.
Along with questions about the safety of ivermectin in human use, policy related to ivermectin may soon change, as it may affect biodiversity and be damaging ecosystems [10, 16]. You can read more about potential policy changes here.