Wang W, Cai C, Qin S, He L, Liang Q, Tang S, Xie J, Long T, Hou J*, Kim W*, Zhao F*. PARP inhibitors and breast cancer: from therapeutic breakthrough to resistance challenge. Experimental and Molecular Medicine. 2026 Apr 10.
Kusuma R, Valerie AR, Qin S, Ichiwa K, Joshua K, Seo G*, Kim W*. Ubiquitin System-Driven Proteostasis in DNA Damage Response. International Journal of Molecular Sciences 2026 Mar 3;27(5):2356.
Christyani G, Cai C, Feng Y, Lee H, Tu X, Zhang C, Lou Z*, Kim W*. ZFP161 promotes colorectal cancer progression by transcriptionally activating c-MYC. Frontiers in Oncology 2026 Feb 18;15:1680561.
Zhao F, Cai C, Gao H, Moon J, Christyani G, Qin S, Hao Y, Liu T, Lou Z*, Kim W*. Monoubiquitination of TopBP1 by PHRF1 enhances ATR activation and genomic stability. Nucleic acids research. 2025 Feb 27;53(5):gkaf073.
He L, Moon J, Cai C, Hao Y, Lee H, Kim W*, Zhao F*, Lou Z*. The interplay between chromatin remodeling and DNA double-strand break repair: Implications for cancer biology and therapeutics. DNA Repair (Amst). 2025 Feb;146:103811.
Diskul-Na-Ayudthaya P, Bae SJ, Bae YU, Van NT, Kim W*, Ryu S*. ANKRD1 Promotes Breast Cancer Metastasis by Activating NF- κ B-MAGE-A6 Pathway. Cancers (Basel). 2024 Sep 27;16(19):3306.
Christyani G, Carswell M, Qin S, Kim W*. An Overview of Advances in Rare Cancer Diagnosis and Treatment. International Journal of Molecular Sciences. 2024 Jan 18;25(2):1201.
Huang M, Qin S, Gao H, Kim W, Xie F, Yin P, John A, Weinshilboum RM, Wang L. The Role of CENPK Splice Variant in Abiraterone Response in Metastatic Castration-Resistant Prostate Cancer. Cells. 2024 Sep 28;13(19):1622.
Qu Y, Qin S, Yang Z, Li Z, Liang Q, Long T, Wang W, Zeng D, Zhao Q, Dai Z, Ni Q, Zhao F, Kim W*, Hou J*. Targeting the DNA repair pathway for breast cancer therapy: Beyond the molecular subtypes. Biomedicine & Pharmacotherapy. 2023 Dec 31:169:115877.
Qin S, Kitty I, Hao Y, Zhao F, Kim W*. Maintaining Genome Integrity: Protein Kinases and Phosphatases Orchestrate the Balancing Act of DNA Double-Strand Breaks Repair in Cancer. International Journal of Molecular Sciences. 2023 Jun 16;24(12)
Moon J, Kitty I, Renata K, Qin S, Zhao F*, Kim W*. DNA Damage and Its Role in Cancer Therapeutics. International Journal of Molecular Sciences. 2023, 24(5), 4741.
Huang J, Wu C, Kloeber JA, Gao H, Gao M, Zhu Q, Chang Y, Zhao F, Guo G, Luo K, Dai H, Liu S, Huang Q, Kim W, Zhou Q, Zhu S, Wu Z, Tu X, Yin P, Deng M, Wang L, Yuan J, Lou Z. SLFN5- mediated chromatin dynamics sculpt higher-order DNA repair topology. Molecular Cell. 2023 Feb 25;S1097-2765(23)00083-7.
Chen L, Hou J, Guo Q, Zeng X, Deng M, Zhao F, Wu M, Tu X, Kloeber J, Huang J, Luo K, Yin P, Kim W*, Lou Z*. LRRK2 inhibition potentiates PARP inhibitor cytotoxicity through inhibiting homologous recombination-mediated DNA double strand break repair. Clinical and Translational Medicine. 2021 Mar;11(3):e341.
Zhao F*, Kim W*, Gao H, Liu C, Zhang Y, Chen Y, Deng M, Zhou Q, Huang J, Hu Q, Chen SH, Nowsheen S, Kloeber JA, Qin B, Yin P, Tu X, Guo G, Qin S, Zhang C, Gao M, Luo K, Liu Y, Lou Z, Yuan J. ASTE1 Orchestrates Shieldin Complex Mediated DNA Repair by Attenuating End Resection. Nature Cell Biology. 2021 Aug;23(8):894-904.
Kim W*, Zhao F*, Gao H, Qin S, Deng M, Kloeber J, Huang J, Zhou Q, Guo G, Gao M, Tu X, Zeng X, Zhu S, Wu Z, Yin P, Kaufmann S, Luo K, Lou Z. USP13 regulates the replication stress response by deubiquitinating TopBP1. DNA repair. (Amst). 2021 Apr;100:103063.
Zhao F*, Kim W*, Kloeber JA, Lou Z. DNA end resection and its role in DNA replication and DSB repair choice in mammalian cells. Experimental and Molecular Medicine. 2020 Oct;52(10):1705-1714.
Kim W*, Zhao F*, Wu R, Nowsheen S, Huang J, Zhou Q, Qin S, Chen Y, Deng M, Guo G, Luo K, Yuan J, Lou Z. Zinc finger protein 161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex. Nature Communications. 2019 Nov 22;10(1):5304.3
Kim W, Ryu J, Kim JE. CCAR2/DBC1 and Hsp60 Positively Regulate Expression of Survivin in Neuroblastoma Cells. International Journal of Molecular Sciences. 2019 Jan 1;20(1). pii: E131.
Kim W, Pyo J, Byeong-Joo Noh, Joo-Won Jeong, Juhie Lee, Kim JE. CCAR2 negatively regulates IL-8 production in cervical cancer cells. Oncotarget. 2017 Dec 13;9(1):1143-1155.
Kim W, Cheon MG, Kim JE. Mitochondrial CCAR2/DBC1 and its binding partner Hsp60 protect neuroblastoma cells from mitochondrial stress. Biochemical and Biophysical Research Communications. 2017 Apr 15;485(4):782-789.
Qin S, Ingle JN, Kim W, Gao H, Weinshilboum RM, Wang L. ZNF423 modulates the AMP-activated protein kinase pathway and metformin response in a single nucleotide polymorphisms, estrogen and selective estrogen receptor modulator dependent fashion. Pharmacogenetics and Genomics. 2021 Sep 1;31(7):155-164.
Zhu S, Chen Z, Jiang D, Wang R, Cheng X, Li D, Xv Q, Zhao F, Kim W, Guo G, Zhao C, Lou Z, Liu H. Mixed-lineage leukemia protein modulates the loading of let-7a onto AGO1 by recruiting RAN. Haematologica. 2021 Jul 1;106(7):1995-1999.
Zhang Y, Yang Q, Zeng X, Wang M, Dong S, Yang B, Tu X, Wei T, Xie W, Zhang C, Guo Q, Kloeber JA, Cao Y, Guo G, Zhou Q, Zhao F, Huang J, Liu L, Zhang K, Wang M, Yin P, Luo K, Deng M, Kim W, Hou J, Shi Y, Zhu Q, Chen L, Hu S, Yue J, Pi G, Lou Z. MET amplification attenuates lung tumor response to immunotherapy by inhibiting STING. Cancer Discovery. 2021 Jun 7;candisc.1500.2020.
Gao M, Guo G, Huang J, Hou X, Ham H, Kim W, Zhao F, Tu X, Zhou Q, Zhang C, Zhu Q, Liu J, Yan Y, Xu Z, Yin P, Luo K, Weroha J, Deng M, Billadeau DD, Lou Z. DOCK7 protects against replication stress by promoting RPA stability on chromatin. Nucleic Acids Research. 2021 Apr 6;49(6):3322-3337.
Guo G, Gao M, Gao X, Zhu B, Huang J, Tu X, Kim W, Zhao F, Zhou Q, Zhu S, Wu Z, Yan Y, Zhang Y, Zeng X, Zhu Q, Yin P, Luo K, Sun J, Deng M, Lou Z. Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling. Nature Communications. 2021 Apr 12;12(1):2187.
Yan Y, Xu Z, Huang J, Guo G, Gao M, Kim W, Zeng X, Kloeber JA, Zhu Q, Zhao F, Luo K, Lou Z. The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization. Nucleic Acids Research. 2020 Dec 16;48(22):12711-12726.
Gao M, Guo G, Huang J, Kloeber JA, Zhao F, Deng M, Tu X, Kim W, Zhou Q, Zhang C, Yin P, Luo K, Lou Z. USP52 regulates DNA end resection and chemosensitivity through removing inhibitory ubiquitination from CtIP. Nature Communications. 2020 Oct 23;11(1):5362.
Huang J, Zhou Q, Gao M, Nowsheen S, Zhao F, Kim W, Zhu Q, Kojima Y, Yin P, Zhang Y, Guo G, Tu X, Deng M, Luo K, Qin B, Machida Y, Lou Z. Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging. Molecular Cell. 2020 Sep 3;79(5):824-835.e5.
Zhou Q, Huang J, Zhang C, Zhao F, Kim W, Tu X, Zhang Y, Nowsheen S, Zhu Q, Deng M, Chen Y, Qin B, Luo K, Liu B, Lou Z, Mutter RW, Yuan J. The bromodomain containing protein BRD-9 orchestrates RAD51-RAD54 complex formation and regulates homologous recombination mediated repair. Nature Communications. 2020 May 26;11(1):2639.
Chen Y, Wu J, Liang G, Geng G, Zhao F, Yin P, Nowsheen S, Wu C, Li Y, Li L, Kim W, Zhou Q, Huang J, Liu J, Zhang C, Guo G, Deng M, Tu X, Gao X, Liu Z, Chen Y, Lou Z, Luo K, Yuan J. CHK2-FOXK axis promotes transcriptional control of autophagy programs. Science Advances. 2020 Jan 1;6(1):eaax5819.
Song Z, Tu X, Zhou Q, Huang J, Chen Y, Liu J, Lee S, Kim W, Nowsheen S, Luo K, Yuan J, Lou Z. A novel UCHL3 inhibitor, perifosine, enhances PARP inhibitor cytotoxicity through inhibition of homologous recombination-mediated DNA double strand break repair. Cell Death & Disease. 2019 May 21;10(6):398.
Wu J, Chen Y, Geng G, Li L, Yin P, Nowsheen S, Li Y, Wu C, Liu J, Zhao F, Kim W, Zhou Q, Huang J, Guo G, Zhang C, Tu X, Gao X, Lou Z, Luo K, Qiao H, Yuan J. USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2. Cancer Letters. 2019 Feb 13. pii: S0304-3835(19)30087-4.
Pyo J, Ryu J, Kim W, Choi J, Jeong JW, Kim JE. The Protein Phosphatase PPM1G Destabilizes HIF-1α Expression. International Journal of Molecular Sciences. 2018 Aug 5;19(8).
Min YH, Kim W, Kim JE. The Aurora kinase A inhibitor TC-A2317 disrupts mitotic progression and inhibits cancer cell proliferation. Oncotarget. 2016 Dec 20; 7(51): 84718-84735.
Lee SD, Kim W, Jeong JW, Park JW, Kim JE. AK-1, a SIRT2 inhibitor, destabilizes HIF-1 and attenuates HIF-1-dependent responses during hypoxia. Cancer Letters. 2016 Apr 1;373(1):138-145.
Kim W, Jeong JW, Kim JE. CCAR2 deficiency augments genotoxic stress-induced apoptosis in the presence of melatonin in non-small cell lung cancer cells. Tumor Biology. 2014 Nov;35(11):10919-29.
Kim W, Choi MJ, Kim JE. The histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle. Cell Cycle. 2014 Feb 6;13(5):726-38
Kim W, Kim JE. Sirtuin 7 is an emerging sirtuin: Deciphering newer roles. Journal of Physiology and Pharmacology. 2013 Oct;64(5):531-4.
Kim W, Kim JE. Deleted in breast cancer 1 (DBC1) deficiency results in apoptosis of breast cancer cells through impaired responses to UV-induced DNA damage. Cancer Letters. 2013 Jun 10;333(2):180-6.
Kim W, Park G, Kim R, Park JW, Kim JE. The deficiency of H3K79 histone methyltransferase DOT1L inhibits cell proliferation. Journal of Biological Chemistry. 2012 Feb 17; 287(8):5588-99.
Choi MJ, Kim W, Cheon MG, Lee CW, Kim JE. Polo-like kinase 1 inhibitor BI2536 causes mitotic catastrophe following activation of the spindle assembly checkpoint in non-small cell lung cancer cells. Cancer Letters. 2015 Feb 28;357(2):591-601.
Cheon MG, Kim W, Choi MJ, Kim JE. AK-1, a specific SIRT2 inhibitor, induces cell cycle arrest by downregulating Snail in HCT116 human colon carcinoma cells. Cancer Letters. 2015 Jan
28;356(2 Pt B):637-45.