Specialisation: Cardiovascular Pharmacology, Contraction Physiology, Proteomics,
Summary of Work in Field/Industry:
· My current research focusses on investigating the molecular mechanisms of nitric oxide signaling pathway at the proteome levels using multipronged approach of mouse genetics, ex vivo mechanistic functional study as well as high throughput mass spectroscopy techniques.
· Expertise in pharmacology, physiology, and proteomics with heavy emphasis in intracellular signal transduction and GPCR signaling directed towards designing therapeutic strategies for cardiovascular disorders. Technical cognizance encompasses fields of Smooth Muscle pharmacology, Integrative Physiology, Contraction Physiology, Proteomics, Biochemistry, Molecular Biology, Bioinformatic Data Analysis (and related softwares) for Mass Spectrometry data and In-Vivo skills.
· 25+ research publications, book chapters and review article in high impact journals (Highest Impact Factor: 11 for Journal Redox Biology).
· 55+ journal article review experience for high impact journals in biochemistry, physiology, and cell biology.
Summary of Top Achievements:
· Published in Redox Biology (Impact Factor 11.8), one of the top scientific journals reporting protein cysteine S-nitrosylation as the novel third functional dimension of nitric oxide signaling in the cardiovascular system to ensure optimal cardiac function.
· Results from my PhD research discovered a novel role of connexin uncouplers as a therapeutic target to rescue the repercussions of acidic stress in vascular model (Mohanty et al., 2018).
· Media coverage for my 2018 paper (Singh et al., 2018; DOI: 10.1152/ajpgi.00233.2017) in ScienceDaily, entitled “Magnetically applied MicroRNAs could one day help relieve constipation” on January 16, 2018. <www.sciencedaily.com/releases/2018/01/180116222453.htm>.
· Awarded Cotswold Postdoctoral Fellowship Award ($50,000), funded by Drexel University (2020).
· Awarded with INSPIRE Predoctoral Fellowship, sponsored by Department of Science & Technology, Govt. Of India, IF 130735 that supported my stipend for PhD program (2013)