1. Jung M*, Kang M*, Kim BS*, Hong J, Kim C, Koh CH, Choi G, Chung Y#, Kim BS#. Nanovesicle-mediated targeted delivery of immune checkpoint blockades to potentiate therapeutic efficacy and prevent side effects. Under review. (*Co-first authors, #Co-corresponding authors)
2. Kim BS*#, Kuen DS*, Koh CH*, Kim HD, Chang SH, Kim S, Jeon YK, Park YJ, Choi G, Kim J, Kang KW, Kim HY, Kang SJ, Hwang S, Shin EC, Kang CY, Dong C, Chung Y#. Type 17 immunity promotes the exhaustion of CD8+ T cells in cancer. Journal for Immunotherapy of Cancer. 2021 Jun;9(6):e002603. Doi:10.1135/jitc-2021-002603. (*Co-first authors, #Co-corresponding authors)
3. Choi G, Park YJ, Cho M, Moon H, Kim D, Kang CY, Chung Y#, Kim BS#. A Critical Role for Th17-derived TGF-β1 in Regulating the Stability and Pathogenicity of Autoimmune Th17 Cells. Experimental & Molecular Medicine. 2021 May; 53(5):993-1004. Doi: 10.1038/s12276-021-00632-9. (#Co-corresponding authors)
4. Choi G, Kim BS, Chang JH, Chung Y. Defining the role of transforming growth factor β1 in Foxp3+ T regulatory cells. Immunity. 2021 Mar 9;54(3):393-394. Doi: 10.1016/j.immuni.2021.02.008.
5. Jeon I, Lee JM, Shin KS, Kang T, Park MH, Seo H, Song B, Koh CH, Choi J, Shin YK, Kim BS, Kang CY. Enhanced Immunogenicity of Engineered HER2 Antigens Potentiates Antitumor Immune Responses. Vaccines (Basel). 2020 Jul 22;8(3):403. doi: 10.3390/vaccines8030403.
6. Choi G, Na H, Kuen DS, Kim BS#, Chung Y#. Autocrine TGF-β1 Maintains the Stability of Foxp3+ Regulatory T Cells via IL-12Rβ2 Downregulation. Biomolecules. 2020 May 27;10(6):819. doi: 10.3390/biom10060819. (#Co-corresponding authors)
7. Kuen DS, Kim BS, Chung Y. IL-17-Producing Cells in Tumor Immunity: Friends or Foes? Immune Network. 2020 Feb 7;20(1):e6. doi: 10.4110/in.2020.20.e6. eCollection 2020 Feb.
8. Koh CH, Kim IK, Shin KS, Jeon I, Song B, Lee JM, Bae EA, Seo H, Kang TS, Kim BS, Chung Y, Kang CY. GITR Agonism Triggers Antitumor Immune Responses through IL21-Expressing Follicular Helper T Cells. Cancer Immunology Research. 2020 May;8(5):698-709. doi: 10.1158/2326-6066.CIR-19-0748. Epub 2020 Mar 2.
9. Kim BS, Clinton J, Wang Q, Chang SH. Targeting ST2 expressing activated regulatory T cells in Kras-mutant lung cancer. Oncoimmunology. 2019 Nov 2;9(1):1682380. doi: 10.1080/2162402X.2019.1682380. eCollection 2020.
10. Song B, Lee JM, Park YJ, Kim IK, Kim BS, Shin KS, Jeon I, Koh CH, Bae EA, Seo H, Byun Y, Kang CY. Differentiation of c-Kit+ CD24+ natural killer cells into myeloid cells in a GATA-2-dependent manner. FASEB Journal. 2020 Mar;34(3):4462-4481. doi: 10.1096/fj.201902662R. Epub 2020 Jan 27.
11. Shin KS, Jeon I, Kim BS, Kim IK, Park YJ, Koh CH, Song B, Lee JM, Lim J, Bae EA, Seo H, Ban YH, Ha SJ, Kang CY. Monocyte-derived dendritic cells dictate the memory differentiation of CD8+ T cells during acute infection. Frontiers in Immunology. 2019 Aug 16;10:1887. doi: 0.3389/fimmu.2019.01887. eCollection 2019.
12. Kim IK, Koh CH, Jeon I, Shin KS, Kang TS, Bae EA, Seo H, Ko HJ, Kim BS, Chung Y, Kang CY. GM-CSF promotes antitumor immunity by inducing Th9 cell responses. Cancer Immunology Research. 2019 Mar;7(3):498-509. doi: 10.1158/2326-6066.CIR-18-0518. Epub 2019 Feb 6.
13. Park YJ, Ryu H, Choi G, Kim BS, Hwang ES, Kim HS, Chung Y. IL-27 confers a protumorigenic activity of regulatory T cells via CD39. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3106-3111. doi: 10.1073/pnas.1810254116. Epub 2019 Feb 4.
14. Bae EA, Seo H, Kim BS, Choi J, Jeon I, Shin KS, Koh CH, Song B, Kim IK, Min BS, Han YD, Shin SJ, Kang CY. Activation of NKT cells in an anti-PD-1-resistant tumor model enhances anti-tumor immunity by reinvigorating exhausted CD8 T cells. Cancer Research. 2018 Jul 16. pii: canres.0734.2018. doi: 10.1158/0008-5472. CAN-18-0734. [Epub ahead of print]
15. Tanaka K, Martinez GJ, Yan X, Long W, Ichiyama K, Chi X, Kim BS, Reynolds JM, Chung Y, Tanaka S, Liao L, Nakanishi Y, Yoshimura A, Zheng P, Wang X, Tian Q, Xu J, O’Malley BW, Dong C. Regulation of pathogenic T helper 17 cell differentiation by steroid receptor
16. Seo H, Kim BS, Bae EA, Min BS, Han YD, Shin SJ, Kang CY. IL21 Therapy combined with PD-1 and Tim-3 blockade provides enhanced NK cell antitumor activity against MHC class I-deficient tumors. Cancer Immunology Research. 2018 Jun; 6(6):685-695. doi: 10.1158/2326-6066. CIR-17-0708. Epub 2018 Apr 3.
17. Lee JE, Lee JM, Park YJ, Kim BS, Jeon YT, Chung Y. Inhibition of autoimmune Th17 cells responses by pain killer ketamine. Oncotarget. 2017 May 31; 8(52):89475-89485. doi: 10.18632/oncotarget.18324. eCollection 2017 Oct 27.
18. Wang X, Ni L, Chang D, Lu H, Jiang Y, Kim BS, Wang A, Liu X, Zhong B, Yang X, Dong C. Cyclic AMP-Responsive Element-Binding Protein (CREB) is Critical in Autoimmunity by Promoting Th17 but inhibiting Treg Cell Differentiation. EBioMedicine. 2017 Nov;25:165-174. doi: 10.1016/j.ebiom.2017.10.010. Epub 2017 Oct 12.
19. Cho M, Lee JE, Lim H, Shin HW, Khalmuratova R, Choi G, Kim HS, Choi WS, Park YJ, Shim I, Kim BS, Kang CY, Kim JO, Tanaka S, Kubo M, Chung Y. Fibrinogen cleavage products and Toll-like receptor 4 promote the generation of programmed cell death 1 ligand 2-positive dendritic cells in allergic asthma. Journal of Allergy and Clinical Immunology. 2017 Oct 14. pii: S0091-6749(17)31582-8. doi: 10.1016/j.jaci.2017.09.019.
20. Kim BS, Lu H, Ichiyama K, Chen X, Zhang YB, Mistry NA, Tanaka K, Lee YH, Nurieva R, Zhang L, Yang XO, Chung Y, Jin W, Chang SH, Donc C. Generation of RORγt+ antigen-specific T regulatory 17 cells from Foxp3+ precursors in autoimmunity. Cell Reports. 2017 Oct;21:195-207
21. Lee YH, Martin-Orozco N, Zheng P, Li J, Zhang P, Tan H, Park HJ, Jeong M, Chang SH, Kim BS, Xiong W, Zang W, Guo L, Liu Y, Dong ZJ, Overwijk WW, Hwu P, Yi Q, Kwak L, Yang Z, Mak TW, Li W, Radvanyi LG, Ni L, Liu D, Dong C. Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function. Cell Research. 2017 Aug;27(8):1034-1045. doi: 10.1038/cr.2017.90. Epub 2017 Jul 7.
22. Choi G, Kim BS, Park YJ, Shim I, Chung Y. Clonal Expansion of Allergen-specific CD4+ T Cell in the Lung in the Absence of Lymph Nodes. Immune Network. 2017 Jun;17(3):163-170. doi: 10.4110/in.2017.17.3.163. Epub 2017 Jun 20.
23. Seo H, Jeon I, Kim BS, Park M, Bae EA, Song B, Koh CH, Shin KS, Kim IK, Choi K, Oh T, Min J, Min BS, Han YD, Kang SJ, Shin SJ, Chung Y, Kang CY. IL-21-mediated reversal of NK cell exhaustion facilitates anti-tumour immunity in MHC class I-deficient tumours. Nature Communications. 2017 Jun 6;8:15776. doi: 10.1038/ncomms15776.
24. Kim YU*, Kim BS*, Lim H, Wetsel RA, Chung Y. Enforced expression of CXCR5 drives T follicular regulatory-like features in Foxp3+Tcells. Biomolecules & Therapeutics. 2017 Mar 1;25(2):130-139. doi: 10.4062/biomolther.2016.075. (*Co-first authors).
25. Kim BS*, Park YJ*, Chung Y. Targeting IL-17 in autoimmunity and inflammation. Archives of Pharmacal Research. 2016 Aug 30. [Epub ahead of print] Review. (*Co-first authors).
26. Ichiyama K, Gonzalez-Martin A, Kim BS, Jin HY, Jin W, Xu W, Sabouri-Ghomi M, Xu S, Zheng P, Xiao C, Dong C. The MicroRNA-183-96-182 Cluster Promotes T Helper 17 Cell Pathogenicity by Negatively Regulating Transcription Factor Foxo1 Expression. Immunity. 2016 Jun 21;44(6):1284-98. doi: 10.1016/j.immuni.2016.05.015.
27. Kim IK, Kim BS, Koh CH, Seok JW, Shin KS, Bae EA, Lee GE, Jeon H, Cho J, Jung Y, Han D, Kwon BS, Lee HY, Chung Y, Kang CY. GITR costimulation facilitates tumor regression by inducing IL-9-producing helper T cells. Nature Medicine. 2015 Sep;21(9):1010-7. doi: 10.1038/nm.3922. Epub 2015 Aug 17.
28. Ichiyama K, Chen T, Wang X, Yan X, Kim BS, Tanaka S, Ndiaye-Lobry D, Deng Y, Zou Y, Zheng P, Tian Q, Aifantis I, Wei L, Dong C. The methylcytosine dioxygenase Tet2 promotes DNA demethylation and activation of cytokine gene expression in T cells. Immunity. 2015 Apr 21;42(4):613-26. doi: 10.1016/j.immuni.2015.03.005. Epub 2015 Apr 7.
29. Chung Y, Yamazaki T, Kim BS, Zhang Y, Reynolds JM, Martinez GJ, Chang SH, Lim H, Birkenbach M, Dong C. Epstein Barr Virus-Induced 3 (EBI3) Together with IL-12 Negatively Regulates T Helper 17-Mediated Immunity to Listeria monocytogenes Infection. PLoS Pathogen. 2013 Sep;9(9):e1003628. doi:10.1371/journal.ppat.1003628. Epub 2013 Sep 19.
30. Yang XO, Zhang H, Kim BS, Niu X, Peng J, Chen Y, Kerketta R, Lee YH, Chang SH, Corry DB, Wang D, Watowich SS, Dong C. The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation. Nature Immunology. 2013 Jul;14(7):732-40. doi: 10.1038/ni.2633. Epub 2013 Jun 2.
31. Kim BS, Kim IK, Park YJ, Kim YS, Kim YJ, Chang WS, Lee YS, Kweon MN, Chung Y, Kang CY. Conversion of Th2 memory cells into Foxp3+ regulatory T cells suppressing Th2-mediated allergic asthma. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8742-7. doi: 10.1073/pnas.0911756107. Epub 2010 Apr 26.
32. Chung Y, Chang JH, Kim BS, Lee JM, Kim HY, Kang CY. Anatomic location defines antigen presentation by dendritic cells to T cells in response to intravenous soluble antigens. European Journal of Immunology. 2007 Jun;37(6):1453-62.
33. Chung Y, Kim BS, Kim YJ, Ko HJ, Ko SY, Kim DH, Kang CY. CD1d-restricted T cells license B cells to generate long-lasting cytotoxic antitumor immunity in vivo. Cancer Research. 2006 Jul 1;66(13):6843-50.