RESEARCH INTERESTS

• MICROBIOLOGY: Securing novel or functional microbial resources

• MICROBIAL GENOMICS: Discovering genetic resources based on microbial genomes and genome mining for biosynthetic genes

• NATURAL PRODUCT BIOSYNTHESIS: Elucidating the functional characteristics of the biosynthetic genes involves in the interested natural products and developing the novel metabolites by employing combinatorial biosynthesis track

• FERMENTATION: Industrializing the targeted microbial metabolites by optimizing the downstream process including the fermentation conditions

CURRENT PROJECTS

• Elucidation of microbial azasugar biosynthesis (focused on 1-deoxynojirimycin) and generation of its derivatives for antidiabetic biomaterials

• Discovery and biosynthesis of natural microbial carotenoids (focused on C30 and C50 carotenoids) for antioxidant biomaterials

• Developments of safe functional biomaterials via Corynebacterium glutamicum factory system

• Discovery and development of microbial consortium for efficient biodegradation of non-hydrolysable plastics

BASIC INFORMATION

• Research fields : Microbiology, Microbial Genomics, Biological Chemistry, Natural Product Biosynthesis, Fermentation

• Contacts : mjseo@inu.ac.kr (email), +82-32-835-8267 (phone)

• Lab : Microbial Biotechnology Laboratory (https://sites.google.com/site/mblabinu)

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Group Website

RESEARCH INTERESTS

• Chemical biology of DNA and RNA

• Design of innovative DNA- and RNA-based architectures

• Novel nucleic acid amplification techniques: RCA, LAMP, SDA, HCR, RPA, NASBA, EXPAR, etc.

• Exploring new hybrid nanobio materials

• Expanding to diagnostic and care systems: biomolecular detection, bioimaging, molecular diagnostics

• Expanding new materials to advanced therapy: gene/drug/vaccine (adjuvant) delivery

CURRENT PROJECTS

• Development of multivalent designer nucleic acid nanoarchitectures for rapid response to viral infectious diseases

• Development of vaccine delivery agents and adjuvant nanoplatforms against infectious diseases

• Development of an early diagnostic system of peritoneal fibrosis by multiplex detection of exosomal nucleic acids and protein markers

• Development of one-step cascade isothermal molecular diagnostic systems for rapid and precise detection of viral infection

BASIC INFORMATION

• Research fields : Nucleic Acid Nanoengineering, Nanomedicine, Biosensing and diagnostics, Drug delivery

• Contacts : e.kim@inu.ac.kr (email), +82-32-835-8849 (phone)

• Lab : Functional Nucleic Acid Nanomaterials Laboratory (https://www.funnanolab.org)

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Group Website

RESEARCH INTERESTS

• Redesigning biological systems through synthetic biology and artificial evolution platforms for i) production of chemicals and pharmaceuticals ii) manipulation of microbiome for therapeutic purposes and iii) diagnosis of diseases

• Synthetic Biology

• Artificial Evolution of Cells and Biomolecules

• Metabolic Engineering

• Microbiome Engineering

• Molecular Diagnosis

CURRENT PROJECTS

• Engineering of microorganisms for direct conversion of macroalgae into value-added chemicals

• Development of biosensor systems for screening of plastic-degrading microorganisms and enzymes

• Development of engineered live biotherapeutic products (eLBPs) for the treatment of chronic metabolic diseases

• Development of next-generation molecular diagnosis platform

BASIC INFORMATION

• Research fields : Synthetic Biology, Artificial Evolution of Cells and Biomolecules, Metabolic Engineering, Microbiome Engineering, Molecular Diagnosis

• Contacts : sjang@inu.ac.kr (email), +82-32-835-8033 (phone)

• Lab : Synthetic Biology and Evolutionary Bioengineering (https://www.sjanglab.org)

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Group Website