OUR PORTFOLIO

Vaccine Design Against Human Parainfluenza Virus Type 3

Objective: Computational Vaccine Development

Tools: IEDB, SAVESv6.1, GALAXY WEB, ALLERTOP, VAXIJEN, ALPHAFOLD, DISCOVERY STUDIO, C-IMMSIM, HDOCK, CLUSPRO, GROMACS

Results: 6 Vaccines Developed, One Vaccine Proved To Be Most Effective Against This Virus

Outcome: Vaccine construct 6 proved most effective in Molecular Docking and MD Stimulation

Drug Design Against Lung Cancer

Objective: Computational Drug Development

Tools: PDB, PUBCHEM, DISCOVERY STUDIO, PYMOL, PYRX, AUTODOCK VINA, PROTOX, SWISSADME, ADMETLAB, GROMACS

Results: To Develop An Effective Drug Against Lung Cancer Using EGFR Protein and Flavonoids' derivatives as ligands

Outcome: A drug Baicalein proved strong Binding Affinity and Biological Activity During Molecular Docking and MD Stimulation

Drug Design Against SARC-Cov-2 And Hepatitis C- Repurposing Study With Genome Analysis

Objective: Validation of In-Vitro Studies And Computational Drug Development, Identification of Variants and Mutations In the Genome of Several Variants of SARC-COV-2, Why Some Patients With COVID-19 Tested Positive For Hepatitis C.

Results: In-Silico Study Undergoing 

Comparative pan-genome and resistome analysis of Acinetobacter baumanni strains to identify virulence, resistance, and secondary metabolite gene clusters 

Objectives: 

• To analyze the genomic diversity of multiple strains of Pseudomonas aeruginosa using whole genome sequencing data.

• To identify and characterize antibiotic resistance genes (resistome) and their distribution across different strains.

• To explore the pan-genome structure, including core and accessory genes, to understand genetic variation.

• To investigate functional genes, pathways, and genomic features involved in virulence and adaptation.

Results: Research Undergoing

Thesis And Manuscript Writing

• Biorefineries and Rural Development: Opportunities and Challenges 

• Microbial Fabrication of Semiconductor Nanoparticles: Mechanism and Applications 

• In-Silico sub-unit vaccine design for Human Parainfluenza virus type 3 - A computational approach 

• In-Silico Drug Design Against Lung Cancer Using EGFR Protein - A Computational Approach 

• CRISPR-Cas9 in Monogenic Blood and Lung Disorders: Translational Advances, Therapeutic Promise, and Ethical Frontiers 

• Detoxification Strategies for Lignocellulosic Biomass from Ethanol Production

Integrated Transcriptomic Analysis of UBE2O, BIRC3, and CBLB During the Hair Follicle Cycle of Cashmere Goats Using RNA-Seq and Functional Genomics