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Innovating Molecular Pathology through Spatial and Computational Biology
About Us
At the Noh Lab, we investigate how molecular and spatial heterogeneity shape the biology of cancer.
By combining molecular pathology, genomics, spatial transcriptomics, and artificial intelligence, we study how tumors evolve, adapt, and interact with their microenvironment.
Our goal is to translate these insights into a deeper understanding of tumor subtypes, cellular ecosystems, and precision diagnostics in oncology.
“Often when you think you’re at the end of something, you’re at the beginning of something else.”
Fred Rogers
Key Interests
Spatial & Molecular Heterogeneity
Spatial & Molecular Heterogeneity
We generate high-resolution maps of cancer ecosystems to uncover spatial and molecular patterns.
Immune & Stromal Architecture
Immune & Stromal Architecture
We characterize immune and stromal landscapes to understand how local microenvironments shape tumor phenotypes.
Multi-Omics Integration
Multi-Omics Integration
We integrate genomic, transcriptomic, and imaging data to build refined molecular classifications of cancer.
Adaptive & Resistance Mechanisms
Adaptive & Resistance Mechanisms
We investigate adaptive processes and resistance mechanisms that limit therapeutic efficacy.
Circulating Tumor Cells for Therapy Monitoring
Circulating Tumor Cells for Therapy Monitoring
We utilize circulating tumor cells from liquid biopsies as dynamic biomarkers for disease monitoring in non-small cell lung cancer.
Contact Information
Please feel free to reach out to us for collaborations or inquiries about our research.
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