Características clínicas y COVID-19
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Tasa de progresión: Los pacientes que desarrollan enfermedades críticas, incluido el síndrome de dificultad respiratoria aguda (SDRA), el inicio de la disnea es relativamente tardío (mediana 6,5 días después del inicio de los síntomas), pero la progresión a SDRA puede ser rápido a partir de entonces (mediana 2.5 días después del inicio de la disnea).
Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, Xiang J, Wang Y, Song B, Gu X, Guan L, Wei Y, Li H, Wu X, Xu J, Tu S, Zhang Y, Chen H, Cao B. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020 Mar 28;395(10229):1054-1062. doi: 10.1016/S0140-6736(20)30566-3. Epub 2020 Mar 11. Erratum in: Lancet. 2020 Mar 28;395(10229):1038. Erratum in: Lancet. 2020 Mar 28;395(10229):1038. PMID: 32171076.
Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, Wu Y, Zhang L, Yu Z, Fang M, Yu T, Wang Y, Pan S, Zou X, Yuan S, Shang Y. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med. 2020 Feb 24. doi: 10.1016/S2213-2600(20)30079-5. Epub ahead of print. Erratum in: Lancet Respir Med. 2020 Apr;8(4):e26. PMID: 32105632; PMCID: PMC7102538.
Arentz M, Yim E, Klaff L, Lokhandwala S, Riedo FX, Chong M, Lee M. Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State. JAMA. 2020 Mar 19:e204326. doi: 10.1001/jama.2020.4326. Epub ahead of print. PMID: 32191259; PMCID: PMC7082763.
Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, Zhao Y, Li Y, Wang X, Peng Z. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020 Feb 7:e201585. doi: 10.1001/jama.2020.1585. Epub ahead of print. PMID: 32031570; PMCID: PMC7042881.
Factores de riesgo para la progresión: La edad parece ser el principal factor de riesgo que predice la progresión a SDRA. Las comorbilidades, fiebre alta (≥39 ° C), antecedentes de tabaquismo y algunas características de laboratorio también predicen la progresión y la muerte por COVID-19.
Liu K, Fang YY, Deng Y, Liu W, Wang MF, Ma JP, Xiao W, Wang YN, Zhong MH, Li CH, Li GC, Liu HG. Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province. Chin Med J (Engl). 2020 Feb 7. doi: 10.1097/CM9.0000000000000744. Epub ahead of print. PMID: 32044814.
Arentz M, Yim E, Klaff L, Lokhandwala S, Riedo FX, Chong M, Lee M. Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State. JAMA. 2020 Mar 19:e204326. doi: 10.1001/jama.2020.4326. Epub ahead of print. PMID: 32191259; PMCID: PMC7082763.
Wu C, Chen X, Cai Y, Xia J, Zhou X, Xu S, Huang H, Zhang L, Zhou X, Du C, Zhang Y, Song J, Wang S, Chao Y, Yang Z, Xu J, Zhou X, Chen D, Xiong W, Xu L, Zhou F, Jiang J, Bai C, Zheng J, Song Y. Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China. JAMA Intern Med. 2020 Mar 13:e200994. doi: 10.1001/jamainternmed.2020.0994. Epub ahead of print. PMID: 32167524; PMCID: PMC7070509.
Clinical Characteristics of Coronavirus Disease 2019 in China-32109013.pdfClinical Course and Outcomes of Critically Ill Patients With SARS-CoV-2 Pneumonia in Wuhan, China A Single-Centered, Retrospective, Observational Study-32105632.pdfHow does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes. By Meredith Wadman, Jennifer Couzin-Frankel, Jocelyn Kaiser, Catherine Matacic. Science Magazine. Apr. 17, 2020 , 6:45 PM
A Familial Cluster of Pneumonia Associated With the 2019 Novel Coronavirus Indicating Person-To-Person Transmission A Study of a Family Cluster-31986261.pdfEpidemiological and Clinical Characteristics of 99 Cases of 2019 Novel Coronavirus Pneumonia in Wuhan, China A Descriptive Study-32007143.pdfClinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China-32031570.pdfClinical Features of Patients Infected With 2019 Novel Coronavirus in Wuhan, China-31986264.pdfClinical Characteristics of Novel Coronavirus Cases in Tertiary Hospitals in Hubei Province-32044814.pdfFactores de riesgo (ver también apartado de pacientes crónicos)
Las comorbilidades que se han asociado con enfermedad grave y mortalidad incluyen Enfermedad cardiovascular, Diabetes mellitus, Hipertensión, Enfermedad pulmonar crónica, Cáncer, Enfermedad renal crónica, pacientes inmunodeprimidos
Are patients with hypertension and diabetes mellitus at increased risk for COVID-19? - PMID32171062.pdfPrevalence of Underlying Diseases in Hospitalized Patients with COVID-19- a Systematic Review and MetaAnalysis-32232218.pdfClinical Course and Risk Factors for Mortality of Adult Inpatients With COVID-19 in Wuhan, China A Retrospective Cohort Study-32171076.pdfCare of patients with Pulmonary Arterial Hypertension during the Coronavirus (COVID-19) Pandemic.pdfCancer Patients in SARS-CoV-2 Infection A Nationwide Analysis in China-32066541.pdfClinical Characteristics of 113 Deceased Patients With Coronavirus Disease 2019 Retrospective Study-32217556.pdfEpidemiology of Covid-19 in a Long-Term Care Facility in King County, Washington-32220208.pdfEpidemiological and Clinical Characteristics of 99 Cases of 2019 Novel Coronavirus Pneumonia in Wuhan, China A Descriptive Study-32007143.pdfCase-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy-32203977.pdfClinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China-32031570.pdfAssociation of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China-32211816.pdfHallazgos de laboratorio (ver también carpeta de hematología (Test y hallazgos)
Las características de laboratorio asociadoas con peores resultados son: Linfopenia, enzimas hepáticas elevadas, Lactato deshidrogenasa elevada (LDH), marcadores inflamatorios elevados (p. Ej., Proteína C reactiva [PCR], ferritina), Dímero D elevado (> 1 mcg / mL), Tiempo elevado de protrombina (PT), Troponina elevada, Creatina fosfoquinasa elevada (CPK) y Lesión renal aguda.
Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China-32167524.pdfImpacto de la edad
China coronavirus Six questions scientists are asking.pdfreducing mortality.pdf2019-Novel Coronavirus.pdfCoronaviruses a paradigm of new emerging zoonotic diseases.pdfReal-time tentative assessment of the epidemiological characteristics of novel coronavirus infections in Wuhan.pdfSARSCoV2 a novel deadly virus in a globalised world.pdfThe COVID‐19 epidemic.pdfA Novel Coronavirus Emerging in China Key Questions for Impact Assessment.pdfUpdated understanding of the outbreak of 2019 novel coronavirus.pdfClinical features of patients infected with 2019 novel coronavirus in Wuhan.pdfIs COVID-19 receiving ADE from other coronaviruses.pdfSimilarity in Case Fatality Rates (CFR) of COVID19 SARSCOV2 in Italy and China.pdfPacientes asintomáticos
Japanese National Institute of Infectious Diseases. Field Briefing: Diamond Princess COVID-19 Cases, 20 Feb Update. https://www.niid.go.jp/niid/en/2019-ncov-e/9417-covid-dp-fe-02.html
Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China-32031570.pdfAunque la Biblioteca del Hospital Universitario de Getafe se encuentra cerrada, seguimos dando servicio a nuestros usuarios por los diferentes canales virtuales de que disponemos. Seguimos dando acceso a los recursos de información, proporcionando artículos, realizando búsquedas bibliográficas y mucho más.
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