Publications

Research Papers

2024

Verma TP, Adhikari S, Kandpal M and Jha HC. Differential effects of areca nut, tobacco, and lime on oral squamous cell carcinoma progression. Front. Cancer Control Soc. 2024,  https://doi.org/10.3389/fcacs.2024.1414881 

Bhowmik S, Baral B, Rit T, Jha HC and Das AK. Design and synthesis of nucleobase functionalized peptide hydrogel: In vitro assessment of anti-inflammatory and wound healing effects. Nanoscale, 2024, https://doi.org/10.1039/D4NR01149J 

Baral B, Muduli K, Jakhmola S, Saini V, Kundu P, Rout NK, Patro S, Mohakud NK , and Jha HC. Case study: COVID-19 severity in diabetic patients with and without seizure. International and Life Course Aspects of COVID-19, 2024, https://doi.org/10.1016/B978-0-323-95648-2.00060-5 

Baral D, Saini V, Kandpal M, Kundu P, Dixit AK, Parmar HS, Meena AK, Trivedi P, Jha HC. The Interplay of Co-infections in Shaping COVID-19 Severity: Expanding the Scope Beyond SARS-CoV-2, Journal of Infection and Public Health, 2024, 102486, https://doi.org/10.1016/j.jiph.2024.102486 

Sahu B, Chakrabarty S, Saini V, Kandpal M, Goel B, Kumari S, Ahmed I, Jha HC, Jain SK. Exploring the cytotoxic potential of biflavones of Araucaria cunninghamii: Precise identification combined by LC-HRMS-metabolomics and database mining, targeted isolation, network pharmacology, in vitro cytotoxicity, and docking studies. Chemical Biology & Drug Design 2024. https://doi.org/10.1111/cbdd.14564 

Kinger S, Jagtap YA, Dubey AR, Kumar P, Choudhary A, Karmakar S, Lal G, Prajapti VK, Jha HC, Gutti RK, and Mishra A. Valproate Mediated Proteasome Dysfunctions Induce Apoptosis. Advanced Therapeutics 2024. https://doi.org/10.1002/adtp.202300421 

Verma TP, Adhikari S, Singh S, Rani C, Kumar R, Jha HC. A comprehensive analysis of metabolomics and lipidomics in areca nut mediated oral submucous fibrosis progression through LCMS and Raman spectroscopy. Journal of Raman Spectroscopy 2024. https://doi.org/10.1002/jrs.6679 

Rele S, Thakur CK, Khan F, Baral B, Saini V, Karthikeyan C, Moorthy NS and Jha HC. Curcumin coating: a novel solution to mitigate inherent carbon nanotube toxicity. J Mater Sci: Mater Med 35, 24 (2024). https://doi.org/10.1007/s10856-024-06789-9 

Singh S, Varshney, Singothu S, Bhandari V, and Jha HC. Influence of chlorpyrifos and endosulfan and their metabolites on the virulence of Helicobacter pylori. Environmental Pollution. (2024) 347, (123676) https://doi.org/10.1016/j.envpol.2024.123676 

Rani A, Patra P, Verma TP, Singh A, Jain AK, Jaiswal N, Narang S, Mittal N, Parmar HS, and Jha HC. Deciphering the Association of Epstein−Barr Virus and Its Glycoprotein M Peptide with Neuropathologies in Mice. ACS Chemical Neuroscience. (2024) https://doi.org/10.1021/acschemneuro.4c00012 

Kashyap D, Tanwar M, Rani C, Bagde PH, Singh S, Varshney N, Saini V, Mishra A, Kumar R, and Jha HC. Spectroscopic assessment of biomolecular changes in Helicobacter pylori and Epstein–Barr virus co-infected gastric epithelial cells. Journal of Raman Spectroscopy. (2024) https://doi.org/10.1002/jrs.6652 

Indari O ; Ghosh S; Bal A; Brown JR.; Garg M; Mishra A; Karmodiya K; Jha HC. Awakening the Sleeping Giant: Epstein-Barr Virus Reactivation by Biological Agents. Pathogens and Disease Vol. 82, 2024, https://doi.org/10.1093/femspd/ftae002 

Kandpal M, Baral B, Varshney N, Jain AK, Chatterji D, Meena AK, Pandey RK, Jha HC. Gut-Brain Axis Interplay via STAT3 pathway: Implications of Helicobacter pylori derived Secretome on inflammation and Alzheimer's disease. Virulence (2024) https://doi.org/10.1080/21505594.2024.2303853 

Rani A, Ergün S, Karnati S, Jha HC. Understanding the link between neurotropic viruses, BBB permeability, and MS pathogenesis. Journal of NeuroVirology (2024) 10.1007/s13365-023-01190-8 

2023

Kumar P, Kinger S, Dubey AR, Jagtap YA, Choudhary A, Prasad A, Jha HC, Dhiman R, Gutti RK and Mishra A. Trehalose Promotes Clearance of Proteotoxic Aggregation of Neurodegenerative Disease-Associated Aberrant Proteins. Molecular Neurobiology. (2023) https://doi.org/10.1007/s12035-023-03824-8 

Kashyap D, Koirala S, Roy R, Saini V, Varshney N, Bagde PH, Samanta S, Kar P, and Jha HC. Computational Insights into VacA Toxin Inhibition: Harnessing FDA-Approved Antibiotics against Helicobacter pylori. Journal of Biomolecular Structure and Dynamics. (2023), https://doi.org/10.1080/07391102.2023.2278080 

Agarwal V, Varshney N, Singh S, Kumar N, Chakraborty A, Sharma B, Jha HC, and Sarma TK. Cobalt-Adenosine Monophosphate Supramolecular Hydrogel with pH-Responsive Multi-Nanozymatic Activity. ACS Appl. Bio Mater. (2023), https://doi.org/10.1021/acsabm.3c00719 

Tripathi V, Jaiswal P, Verma R, Sahu K, Majumder S, Chakraborty S, Jha HC, Parmar HS. Therapeutic influence of simvastatin on MCF-7 and MDA-MB-231 breast cancer cells via mitochondrial depletion and improvement in  chemosensitivity of cytotoxic drugs. Advances in Cancer Biology - Metastasis. (2023), https://doi.org/10.1016/j.adcanc.2023.100110 

Varshney N, Murmu S, Baral B, Kashyap D, Singh S, Kandpal M, Bhandari V, Chaurasia A, Kumar S and Jha HC. Unraveling the Aurora kinase A and Epstein Barr Virus nuclear antigen 1 axis in Epstein Barr Virus associated gastric cancer. Virology. (2023), https://doi.org/10.1016/j.virol.2023.109901 

Rani A, Tanwar M, Verma T, Patra P, Trivedi P, Kumar R and Jha HC. Understanding the role of membrane cholesterol upon Epstein Barr virus infection in astroglial cells. Frontiers in Immunology. (2023), https://doi.org/10.3389/fimmu.2023.1192032 

Baral B, Kandpal M, Ray A, Jana A, Yadav DS, Sachin K, Mishra A, Baig MS, and  Jha HC. Helicobacter pylori and Epstein-Barr virus infection in cell polarity alterations. Folia Microbiologica. (2023), https://doi.org/10.1007/s12223-023-01091-7 

Kashyap D, Roy R, Varshney N, Baral B, Bagde PH, Kandpal M, Kumar S, Kar P, and  Jha HC. Withania somnifera extract reduces gastric cancerous properties through inhibition of gankyrin in cellular milieu produced by Helicobacter pylori and Epstein Barr virus. Journal of Biomolecular Structure and Dynamics. (2023), https://doi.org/10.1080/07391102.2023.2252096

Baral B, Saini V, Tandon A, Singh S, Rele S, Dixit AK, Parmar HS, Meena AK, and  Jha HC. SARS-CoV-2 Envelope protein induces necroptosis and mediates inflammatory response in lung and colon cells through Receptor Interacting Protein Kinase 1. Apoptosis. (2023), 10.1007/s10495-023-01883-9

Rani A; Saini V; Patra P; Prashar T; Pandey RK; Mishra A  and  Jha HC.Epigallocatechin Gallate: A multifaceted molecule for neurological disorders and neurotropic viral infections. ACS Chemical Neuroscience. (2023), https://doi.org/10.1021/acschemneuro.3c00368

Saini V, Rani A, Kumar A, Jha K,  Karnati  S and  Jha HC. Altered Synaptic Plasticity: Plausible Mechanisms Associated with Viral Infections. Future Virology. (2023),10.2217/fvl-2023-0105 

Kashyap D, Koirala S, Saini V, Bagde P.H, Samanta S, Kar P and  Jha HC. Prediction of Rab5B inhibitors through integrative in silico techniques. Molecular Diversity. (2023), https://doi.org/10.1007/s11030-023-10693-9 

Varshney N, Kashyap D, Behera S.K, Saini V, Chaurasia A, Kumar S and Jha HC. Predictive profiling of gram-negative antibiotics in CagA oncoprotein inactivation: a molecular dynamics simulation approach. SAR and QSAR in Environmental Research, (2023) 501-521, https://doi.org/10.1080/1062936X.2023.2230876 

Kashyap D, Rele S, Bagde PH, Saini V, Chatterjee D, Jain AK, Pandey RK, and Jha HC. Comprehensive insight into altered host cell‑signaling cascades upon Helicobacter pylori and Epstein–Barr virus infections in cancer. Archives of Microbiology, (2023) 205:262 https://doi.org/10.1007/s00203-023-03598-6 

Patra P, Rani A, Sharma N, Mukherjee C, and Jha HC. Unraveling the Connection of EpsteinBarr Virus and Its Glycoprotein M146157 Peptide with Neurological Ailments. ACS Chemical Neuroscience, 2023/06/09, 10.1021/acschemneuro.3c00231

Sahu B, Ghosh T, Kandpal S, Bansal L, Rani C, Jha HC, Kumar R. Green and Red Luminescent Curcuma and Lawsone Herbal Amalgam as Yellow Emission Source. ChemistrySelect, 2023/4/13, 8(14), https://doi.org/10.1002/slct.202204265 

Rajpoot S, Kumar A, Gaponenko V, Thurston TL, Mehta D, Faisal SM, Zhang KY, Jha HC, Darwhekar GN and Baig MS. Dorzolamide suppresses PKCδ-TIRAP-p38 MAPK signaling axis to dampen the inflammatory response. Future Medicinal Chemistry, (2023), https://doi.org/10.4155/fmc-2022-0260 


Baral B, Muduli K, Jakhmola S, Indari O, Jangir J, Rashid AH, Jain S, Kumar A, Mohapatra AK , Patro S, Parida P, Misra N, Mohanty AP, Sahu BR, Jain AK, Elangovan S, Parmar HS, Tanveer M, Mohakud NK and Jha HC. Redefining Lobe-Wise Ground-Glass Opacity in COVID-19 Through Deep Learning and its Correlation With Biochemical Parameters. IEEE JOURNAL ON BIOMEDICAL AND HEALTH INFORMATICS (JBHI), 10.1109/JBHI.2023.3263431

Baral B, Kashyap D, Varshney N, Verma TP, Jain AK, Chatterji D, Kumar V, Mishra A, Kumar A, Jha HC. Helicobacter pylori isolated from gastric juice have higher pathogenic potential than biopsy isolates. Genes & Diseases, In Press, (2023), https://doi.org/10.1016/j.gendis.2023.03.003

Indari O, Ergün S, Karnati S, Jha HC. Herpesviral interplay with peroxisome: An underexplored viral niche. Genes & Diseases, (2023), ISSN 2352-3042, https://doi.org/10.1016/j.gendis.2023.01.033

Baral B, Kashyap D, Varshney N, Verma TP, Jain AK, Chatterji D, Kumar V, Mishra A, Kumar A, Jha HC. Data on differential pathogenic ability of Helicobacter pylori isolated from distinct gastric niches, Data in Brief, Volume 47, 2023, 108981, ISSN 2352-3409, https://doi.org/10.1016/j.dib.2023.108981

Jagtap YA, Kumar P, Kinger S, Dubey AK, Choudhary A, Gutti RK, Singh R, Jha HC, Poluri KM, Mishra A. Disturb mitochondrial associated proteostasis: Neurodegeneration and imperfect ageing. Frontiers in Cell and Developmental Biology (2023). 10.3389/fcell.2023.1146564

Kashyap D, Varshney N, Baral B, Kandpal M, Indari O, Jain AK, Chatterji D, Kumar S, Parmar HC, Sonawane A, Jha HC. Helicobacter pylori infected gastric epithelial cells bypass cell death pathway through the oncoprotein Gankyrin. Advances in Cancer Biology-Metastasis (12 Jan, 2023). https://doi.org/10.1016/j.adcanc.2023.100087 

2022

Indari O, Rani A, Baral B, Ergun S, Bala K, Karnati S, Jha HC. Modulation of peroxisomal compartment by Epstein-Barr virus. Microbial Pathogenesis. https://doi.org/10.1016/j.micpath.2022.105946 

Indari O, Singh KA, Tiwari D, Jha HC, Jha NA. Deciphering antiviral efficacy of malaria box compounds against malaria exacerbating viral pathogens- Epstein Barr Virus and SARS-CoV-2, an in silico study. Medicine in Drug Discovery (9 Nov, 2022). 10.1016/j.medidd.2022.100146 .

Kandpal M, Indari O, Baral B, Jakhmola S, Tiwari D, Bhandari V, Pandey RK, Bala K, Sonavane A, Jha HC. Dysbiosis of Gut Microbiota from the Perspective of the Gut-Brain Axis: Role in the Provocation of Neurological Disorders. MDPI "metabolites" (3 Nov, 2022). https://doi.org/10.3390/metabo12111064.

Tiwari D, Srivastava G, Indari O, Tripathi V, Siddiqi IM, Jha HC. An in-silico insight into the predictive interaction of Apolipoprotein-E with Epstein-Barr virus proteins and their probable role in mediating Alzheimer’s disease. Journal of Biomolecular Structure and Dynamics (28 Oct, 2022). https://doi.org/10.1080/07391102.2022.2138978.

Dubey AR, Mishra R, Sundaria N, Jagtap YA, Kumar P, Kinger S, Choudhary A, Jha HC, Prasad A, Gutti, RK, Mishra A. Resveratrol Promotes LRSAM1 E3 Ubiquitin Ligase-Dependent Degradation of Misfolded Proteins Linked with Neurodegeneration. International Journal of Experimental Cellular Physiology, Biochemistry and Pharmacology. HTTPS://DOI.ORG/10.33594/000000574

Kashyap, D.; Panda, M.; Baral, B.; Varshney, N.; R, S.; Bhandari, V.; Parmar, H.S.; Prasad, A.; Jha, H.C. Outer Membrane Vesicles: An Emerging Vaccine Platform. Vaccines 2022, 10, 1578. https://doi.org/10.3390/vaccines10101578 

Tripathi V, Jaiswal P, Sahu K, Majumder SK, Kashyap D, Jha HC, Dixit AK, Parmar HS. Repurposing of metabolic drugs and mitochondrial modulators as an emerging class of cancer therapeutics with a special focus on breast cancer. Advances in Cancer Biology - Metastasis, Volume 6, 2022, 100065, ISSN 2667-3940, https://doi.org/10.1016/j.adcanc.2022.100065.

Tiwari D, Murmu S, Indari O, Jha HC, Kumar S. Targeting Epstein-Barr virus dUTPase, an immunomodulatory protein using antiviral, anti-inflammatory, and neuroprotective phytochemicals. Chemistry and Biodiversity. https://doi.org/10.1002/cbdv.202200527 

Jaiswal P, Tripathi V, Assaiya A, Kashyap D, Dubey R, Singh A, Kumar J,  Jha HC, Sharma R, Dixit AK, Parmar HS. Anti-cancer effects of sitagliptin, vildagliptin, and exendin-4 on triple-negative breast cancer cells via mitochondrial modulation. BIOCELL. 10.32604/biocell.2022.021754  

Tiwari D, Mittal N, Jha HC. Unravelling the links between neurodegeneration and Epstein-Barr virus-mediated cell cycle dysregulation. Current Research in Neurobiology. https://doi.org/10.1016/j.crneur.2022.100046.

Jakhmola S, Md Fulbabu Sk, Chatterjee A, Jain K, Kar P, Jha HC. A plausible contributor to multiple sclerosis; presentation of antigenic myelin protein epitopes by major histocompatibility complexes. Computers in Biology and Medicine. https://doi.org/10.1016/j.compbiomed.2022.105856.

Muduli K, Baral B, Jakhmola S, Elangovan S , Jishnu R K. Polakampalli , N.K. Mohakud , Jha HC.  SARS-CoV-2 induced Guillain Barré Syndrome in a child: first case from Odisha, India. Infect Dis Trop Med. 2022;8: e885  

Das K A, Gosh T, Wang S, Kashyap D, Jadhav G R, Rit T, Jha HC and Cousins G B. Self-assembled benzoselenadiazole-capped tripeptide hydrogels with inherent in vitro anti-cancer and anti-inflammatory activity. Chemical Communications DOI https://doi.org/10.1039/D2CC01160C

Indari O, Jakhmola S, Pathak K D, Tanwar M, Kandpal M, Mishra A, Kumar R, and Jha HC. Comparative Account of Biomolecular Changes Post Epstein Barr Virus Infection of the Neuronal and Glial Cells Using Raman Microspectroscopy. ACS Chemical Neuroscience DOI: 10.1021/acschemneuro.2c00081

Kashyap, D., Roy, R., Kar, P., & Jha, H. C. (2022). Plant-derived active compounds as a potential nucleocapsid protein inhibitor of SARS-CoV-2: an in-silico study. Journal of biomolecular structure & dynamics, 1–16. https://doi.org/10.1080/07391102.2022.2072951 

Dubey R K, Patwa M S, Kinger S, Jagtap Y, Kumar P, Singh S, Dhiman R, Jha HC, Mishra A. Improper Proteostasis: Can It Serve as Biomarkers for Neurodegenerative Diseases? Molecular Neurobiology (19 March 2022). DOI: https://doi.org/10.1007/s12035-022-02775-w 

Ghosh T, Kandpal S, Rani C, Pathak K D, Tanwar M, Jakhmola S, Jha HC, Maximov M, Chaudhary A, Kumar R. Synthesizing Luminescent Carbon from Condensed Tobacco Smoke: Bio-Waste for Possible Bioimaging. Canadian Journal of Chemistry (16 February 2022). DOI: https://doi.org/10.1139/cjc-2021-0339

Sonkar C, Hase V, Banerjee D, Kumar A, Kumar R, Jha HC. Post COVID-19 complications, Adjunct therapy Explored, and Steroidal after Effects. Canadian Journal of Chemistry (21 January 2022). DOI: https://doi.org/10.1139/cjc-2021-0247

Sonkar C, Varshney N, Koganti S, Jha HC. Kinases  and therapeutics in pathogen mediated gastric cancer. Molecular Biology Reports (2022). DOI: 10.1007/s11033-021-07063-9  

Indari I, Md Fulbabu Sk, Jakhmola S, Jonniya NS, Jha HC, Kar P. Decoding the host-parasite interactions involved in Cerebral Malaria through glares of molecular dynamics simulations. The Journal of Physical Chemistry B. DOI: 10.1021/acs.jpcb

Parmar HS, Aakruti Nayak, Kataria S, Tripathi Versha, Jaiswal P, Gavel PK, Jha HC, Bhagwat S, Dixit AK, Lukashevich V, Das AK, Sharma R. Restructuring the ONYX-015 adenovirus by using spike protein genes from SARS-CoV-2 and MERS-CoV: Possible implications in breast cancer treatment. Medical Hypotheses. 159 (2022). https://doi.org/10.1016/j.mehy.2021.110750 

2021

Bagulkar B., Hande A., Chaudhary M., Gawande M., Verma T., Patil M., Jha HC. (2021). Evaluation and Assessment of the Expression of DNA Damage Response – Related Molecules in Oral Submucous Fibrosis (OSF) and Oral Squamous Cell Carcinoma (OSCC) with OSF. Journal of Pharmaceutical Research International, 33(64B), 219-225. https://doi.org/10.9734/jpri/2021/v33i64B35421 

Kashyap D, Varshney N, Parmar HC, Jha HC. Gankyrin at the crossroads of cancer diagnosis, disease prognosis, and development of efficient cancer therapeutics. Advances in Cancer Biology- Metastasis. 2022. https://doi.org/10.1016/j.adcanc.2021.100023  

Rani A, Jakhmola S, Karnati S, Parmar HS, Jha HC. Potential entry receptors for human γ-herpesvirus into epithelial cells: A plausible therapeutic target for viral infections. Tumour Virus Res. 2021;12:200227. doi:10.1016/J.TVR.2021.200227

Tiwari D, Singh VK, Baral B, Pathak DK, Jayabalan J, Kumar R, Tapryal, Jha HC. Indication of Neurodegenerative Cascade Initiation by Amyloid-like Aggregate-Forming EBV Proteins and Peptide in Alzheimer’s Disease. ACS Chem. Neurosci. 2021. https://doi.org/10.1021/acschemneuro.1c00584 

Kashyap D, Baral B, Jakhmola S, Singh AK, Jha HC. 2021. Helicobacter pylori and Epstein-Barr virus coinfection stimulates aggressiveness in gastric cancer through the regulation of gankyrin. mSphere 6:e00751-21. https://doi.org/10.1128/mSphere.00751-21. 

Sonkar C, Doharey PK, Rathore AS, Singh V, Kashyap D, Sahoo AK, Mittal N, Sharma B, Jha HC. Repurposing of Gastric Cancer drugs against COVID-19. Computers in Biology and Medicine. https://doi.org/10.1016/j.compbiomed.2021.104826 

Baral B, Muduli K, Jakhmola S, Parida S, Elangovan S, Mohakud NK, Jha HC. COVID-19 Severity among Cancer -COVID Patients with different Types of Cancer: A case series of five patients. Asian pacific journal of Cancer Care. Vol 6. 2021. DOI:10.31557/APJCC.2021.6.S1.117 

Jha HC, Verma SC. Molecular and Cellular interactions between the host and Herpesviruses. Front. Cell. Infect. Microbiol. doi: 10.3389/fcimb.2021.771331 

Jakhmola S, Jonniya NA, Md Fulbabu Sk, Rani A, Kar P, and Jha HC. Identification of Potential Inhibitors against Epstein–Barr Virus Nuclear Antigen 1 (EBNA1): An Insight from Docking and Molecular Dynamic Simulations. ACS Chem. Neurosci. 2021. https://doi.org/10.1021/acschemneuro.1c00350 

Ghosh T, Kandpal S, Rani C, Pathak DK, Tanwar M, Chaudhary A, Jha HC, and Kumar R. Atypical Green Luminescence from Raw Cassia Siamea Extract: A Comparison with Red Emitting Tinospora Cordifolia. ACS Appl. Bio Mater. 2021. https://doi.org/10.1021/acsabm.1c00650 

Kashyap D, Jakhmola S, Tiwari D, Kumar R, Narayana NSHM, Elangovan M, Bras NF, Jha HC. Plant derived active compounds as potential anti SARS-CoV-2 agents: an in-silico study.  Journal of Biomolecular Structure and Dynamics. 10.1080/07391102.2021.1947384

Kaur J, Jakhmola S, Singh RR, Joshi B, Jha HC, Joshi A. Ultrasonic Atomizer-Driven Development of Biocompatible and Biodegradable Poly(d,l-lactide-co-glycolide) Nanocarrier-Encapsulated Suberoylanilide Hydroxamic Acid to Combat Brain Cancer. ACS Appl. Bio Mater. 2021. doi.org/10.1021/acsabm.1c00430. 

Jakhmola S, Upadhyay A, Jain K, Mishra A, Jha HC. 2021 Jun 19. Herpesviruses and the hidden links to Multiple Sclerosis neuropathology. J Neuroimmunol.:577636. doi:10.1016/j.jneuroim.2021.577636. https://linkinghub.elsevier.com/retrieve/pii/S0165572821001636.

Anand U, Jakhmola S, Indari O, Jha HC, Chen Z-S, Tripathi V, Pérez de la Lastra JM. 2021. Potential therapeutic targets and vaccine development for COVID-19 management: A review on the recent update. Front Immunol. 12:2454. DOI: 10.3389/fimmu.2021.658519 

Jakhmola S, Baral B, Jha HC. 2021. A comparative analysis of COVID-19 outbreak on age groups and both the sexes of population from India and other countries. The Journal of Infection in Developing Countries. 15(03):333–341. doi:10.3855/jidc.13698.

Indari O, Baral B, Muduli K, Mohanty AP, Swain N, Mohakud NK, Jha HC. Insights into Plasmodium and SARS-CoV-2 co-infection driven neurological manifestations; Biosafety and Health, 2021, ISSN 2590-0536, https://doi.org/10.1016/j.bsheal.2021.04.001.

Jakhmola S, Jha HC. Glial cell response to Epstein-Barr Virus infection: A plausible contribution to virus-associated inflammatory reactions in the brain. Virology. 2021, ISSN 0042-6822, https://doi.org/10.1016/j.virol.2021.04.005.

Jakhmola S, Indari O, Kashyap D, Varshney N, Das A, Manivannan E, Jha HC. Mutational analysis of structural proteins of SARS-CoV-2. Heliyon. 2021 Mar 20;e06572. https://doi.org/10.1016/j.heliyon.2021.e06572 

Jakhmola S, Baral B, Muduli K, Suar M, Das P, Patnaik PK, Mohakud NK, Jha HC. The interrelation of COVID-19 and neurological modalities. Neurol Sci. 2021 Mar 12 DOI: 10.1007/s10072-021-05177-3

Parmar HS, Nayak A, Gavel PK, Jha HC, Bhagwat S, Sharma R. Cross talk between COVID-19 and breast cancer. Curr Cancer Drug Targets. 2021 Feb 15;

Anand U, Adelodun B, Pivato A, Suresh S, Indari O, Jakhmola S, Jha HC, Jha PK, Tripathi V, Di Maria F. A review of the presence of SARS-CoV-2 RNA in wastewater and airborne particulates and its use for virus spreading surveillance. Environmental Research. 2021 Feb 25;110929. 

Indari O, Jakhmola S, Elangovan M, Jha HC. An update on antiviral therapy against SARS-CoV-2: How far have we come? Frontiers in Pharmacology.  DOI: 10.3389/fphar.2021.632677

Jakhmola S, Hazarika Z, Jha AN, Jha HC. In silico analysis of antiviral phytochemicals efficacy against Epstein–Barr virus glycoprotein H. Journal of Biomolecular Structure and Dynamics, 2021. DOI: 10.1080/07391102.2020.1871074 

2020

Indari O, Chandramohanadas R, Jha HC, Epstein-Barr virus infection modulates blood-brain barrier cells and its co-infection with Plasmodium falciparum induces RBC adhesion, Pathogens and Disease, ftaa080, https://doi.org/10.1093/femspd/ftaa080 

Jakhmola S, Indari O, Kashyap D, Varshney N, Rani A, Sonkar C, Baral B, Chatterjee S, Das A, Kumar R, Jha HC. Recent updates on COVID-19: A holistic review. Heliyon. 2020 Dec 1;6(12). Link: https://www.cell.com/heliyon/abstract/S2405-8440(20)32549-4

Sangtani R, Ghosh A, Jha HC, Parmar HS, Bala K. Potential of algal metabolites for the development of broad-spectrum antiviral therapeutics: Possible implications in COVID-19 therapy. Phytotherapy Research. 2020;1–21. Link: https://onlinelibrary.wiley.com/doi/abs/10.1002/ptr.6948

Tiwari D, Jakhmola S, Pathak DK, Kumar R, Jha HC. Temporal In Vitro Raman Spectroscopy for Monitoring Replication Kinetics of Epstein–Barr Virus Infection in Glial Cells. ACS Omega. (2020) Link: https://doi.org/10.1021/acsomega.0c04525

​Sonkar C, Kashyap D, Varshney N, Baral B, & Jha HC. Impact of Gastrointestinal symptoms in COVID-19: A molecular approach. SN Compr. Clin. Med. (2020). https://doi.org/10.1007/s42399-020-00619-z Link: https://link.springer.com/article/10.1007%2Fs42399-020-00619-z

Kaushik R, Rani C, Neeshu K, Tanwar M, Pathak DK, Chaudhary A, Siraj F, Jha HC, Kumar R. Brain Tumour Detection and Grading Using Raman Scattering: Analogy from Semiconductors for Solving Biological Problem. Advances in Materials and Processing Technologies. 2020 Oct 17;0(0):1–12. Link: https://www.tandfonline.com/doi/full/10.1080/2374068X.2020.1829959

Sonkar, C., Verma, T., Chatterji, D., Jain A., K., Jha H., C. Status of kinases in Epstein-Barr virus and Helicobacter pylori Coinfection in gastric Cancer cells. BMC Cancer 20, 925 (2020). https://doi.org/10.1186/s12885-020-07377-0 Link: https://bmccancer.biomedcentral.com/articles/10.1186/s12885-020-07377-0#Abs1

Jakhmola, S., Indari, O., Chatterjee, S., and Jha H.C. SARS-CoV-2, an Underestimated Pathogen of the Nervous System. SN Compr. Clin. Med. (2020). doi: https://doi.org/10.1007/s42399-020-00522-7. Link: https://link.springer.com/article/10.1007/s42399-020-00522-7

​Pei Y, Wong JH, Jha HC, Tian T, Wei Z, Robertson ES. Epstein-Barr Virus facilitates expression of KLF14 by regulating the cooperative binding of E2F-Rb-HDAC complex in latent infection. Journal of Virology. 2020 Aug 26. Link: https://jvi.asm.org/content/early/2020/08/21/JVI.01209-20

​Jakhmola S, Indari O, Baral B, Kashyap D, Varshney N, Das A, Chatterjee S, Jha HC. Comorbidity assessment is essential during COVID-19 treatment. Frontiers in physiology. 2020;11. doi: 10.3389/fphys.2020.00984 Link:https://www.frontiersin.org/articles/10.3389/fphys.2020.00984/abstract

​Kumar R, Jha H C, pH boosters/regulator as a potential candidate in managing COVID19. https://science.sciencemag.org/content/367/6483/1260/tab-e-letters

​Pei, Y., Hwang, N., Lang, F., Zhou, L., Wong, J.H.Y., Singh, R.K., Jha, H.C., El-Deiry, W.S., Du, Y. and Robertson, E.S., 2020. Quassinoid analogs with enhanced efficacy for treatment of hematologic malignancies target the PI3Kγ isoform. Communications Biology, 3(1), pp.1-13. https://doi.org/10.1038/s42003-020-0996-z 

​Kashyap D, Baral B, Verma TP, Sonkar C, Chatterji D, Jain AK, Jha HC*. Oral rinses in growth inhibition and treatment of Helicobacter pylori infection. BMC microbiology. 2020;20(1):1-8. https://doi.org/10.1186/s12866-020-01728-4

​2018

​Lang F, Sun Z, Pei Y, Singh RK, Jha HC. , Robertson ES. Shugoshin 1 is dislocated by KSHV-encoded LANA inducing aneuploidy. PLoS Pathogen,  2018;14(9):e1007253.

​Singh, R. K., Lang, F., Pei, Y., Jha, HC., & Robertson, E. S. (2018). Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia. PLoS pathogens, 14(5), e1007062.

Pandey, S., Jha, H. C., Shukla, S. K., Shirley, M. K., & Robertson, E. S. (2018). Epigenetic Regulation of Tumor Suppressors by Helicobacter pylori Enhances EBV-Induced Proliferation of Gastric Epithelial Cells. mBio, 9(2), e00649-18.

Singh S, Jha HC*. Optical Imaging with Signal Processing for Non-Invasive Diagnosis in Gastric Cancer: Nonlinear Optical Microscopy Modalities. Advances in Intelligent Systems and Computing. Springer Nature Singapore Pte Ltd. 2018, 748; 609-620. 

2017

Pei Y., Banerjee S., Jha HC, Sun Z, Robertson ES. An essential EBV latent antigen 3C binds Bcl6 for targeted degradation and cell proliferation. PLoS Pathog. 2017 Jul 24;13(7):e1006500. 

Singh, S., & Jha, H. C. Status of Epstein-Barr Virus Coinfection with Helicobacter pylori in Gastric Cancer. Journal of Oncology, 2017, 1–17. https://doi.org/10.1155/2017/3456264

2016

Kumar R, Jha HC, Raut S. JAK2, CALR, MPL mutations: triple negative primary- or secondary- myelofibrosis? Blood. 2016, Doi.org/10.1182/blood-2014-05-578435-E-letters. JIF: 11.8.

Jha HC, Pei Y, Robertson ES. EBV latency and transformation: an overview. Front. Microbiol. 2016. 7:1602. doi: 10.3389/fmicb.2016.01602. JIF:4.1.

Pei Y, Banerjee S, Sun Z, Jha HC, Robertson ES. E2F6 regulation through EBNA3C in EBV associated B cell malignancy. PLoS Pathog 2016, 12(8): e1005844. doi:10.1371/journal. ppat.1005844. JIF:8.0.

Jha HC, Sun Z, Upadhayay SK, El-Naccache D, Robertson ES. KSHV-mediated regulation of Par3 and SNAIL contributes to cell transformation. PLoS Pathog 2016, 12(7): e1005801. doi: 10.1371/journal.ppat.1005801, JIF:8.0.

Sun Z, Jha HC, Pei Y, Robertson ES. Involvement of RIG family proteins in KSHV induced malignancy. Journal of Virology, 2016 (Doi: JVI.01079-16). JIF:4.7.

Shukla SK±, Jha HC±, El-Naccache D, Robertson ES. Role of amino acid 130-159 amino terminus domain of EBNA3C during early EBV infection. Oncotarget, 2016, DOI: 10.18632/oncotarget.7502. JIF:6.6, ± Equal contribution.

Jha HC±, Banerjee S±, Robertson ES. Role of Gammaherpesviruses in Cancer Pathogenesis. Pathogens 2016, 5(1), 18; ± Equal contribution. JIF: NA.

Jha HC±, Mehta D±, Lu J, El-Naccache D, Shukla S, Kovacsics C, Kolson D, Robertson ES. Gammaherpesvirus infection in neuronal cells. mBio 6(6): e01844-15. doi:10.1128/mBio. 01844-15), JIF:6.8 ± Equal contribution.

2015

Saha A±, Jha HC±, Upadhayay S, Robertson ES. Epigenetic silencing of tumor suppressor genes during in vitro Epstein-Barr virus infection. PNAS 2015 Sep 15;112(37): E5199-207, JIF:9.8. ± Equal contribution.

Jha HC±, Shukla SK±, Lu J, Aj MP, Banerjee S, Robertson ES. Dissecting the roles of  EBNA3C domains important for EBV-induced B-cell growth and proliferation. Oncotarget. 2015 Oct 6;6(30):30115-29, JIF:6.6. ± Equal contribution.

Sun Z, Jha HC, Robertson ES. LANA mediated Bub1 recruits PCNA during KSHV latent replication and DNA translasion synthesis. J Virol. 2015 Oct 15;89(20):10206-18, JIF: 4.7

Jha HC, Yang K, El-Naccache D, Sun Z, Robertson ES. EBNA3C regulates p53 through induction of Aurora Kinase B. Oncotarget, 2015 Oncotarget, 6(8), 5788-5803. JIF:6.6.

Uppal T, Jha HC, Verma SC, Robertson ES. Chromatinization of the KSHV genome during KSHV life cycle. Cancers 2015, 7(1), 112-142. JIF: NA.

Banerjee S±, Jha HC ±, Robertson ES. Regulation of the metastasis suppressor Nm23-H1 by tumor viruses. Naunyn-Schmiedeberg's Arch Pharmacol (2015) 388:207–224, JIF:2.3.  ± Equal contribution.

2014

Jha HC±, Lu J±, Verma SC, Banergee S, Mehta D, Robertson ES. KSHV genome programming during the early stages of primary blood mononuclear cell infection. mBio. 2014, 5(6): e02261-14, JIF:6.9, ± Equal contribution.

Dzeng RK±, Jha HC±, Lu J, Saha A, Banergee S, Robertson ES. Small Molecule Growth Inhibitors of Human Oncogenic Gammaherpesvirus Infected B-Cells. Molecular Oncology. 2015; 9: 365-376, JIF:5.9, ± Equal contribution.

Simbiri KO, Jha HC, Kayembe MK, Kovarik C, Robertson ES. Oncogenic viruses associated with Vulva Cancer in HIV-1 patients in Botswana. Infectious Agents and Cancer. 2014; 9:28. JIF:2.37.

Banerjee S, Lu J, Cai Q, Sun Z, Jha HC, Robertson ES. EBNA3C augments Pim-1mediated phosphorylation 1 and degradation of p21 to promote B-cell proliferation. PLoS Pathog. 2014;10(8): e1004304. JIF:8.0.

Sun Z, Xiao B, Jha HC, Lu J, Banerjee S, Robertson ES. KSHV encoded LANA can induce chromosomal instability through targeted degradation of the mitotic checkpoint kinase Bub1. J Virol. 2014; 88(13):7367-78. JIF:4.7.

Lu J, Jha HC, Verma SC, Sun Z, Banerjee S, Dzeng R, Robertson ES. KSHV encoded LANA contributes to viral genome replication by activating the phosphorylation of Survivin. J Virol. 2014; 88(8): 4204-17. JIF:4.7.

Jha HC ±, Prasad M ±, Saha A, Banerjee S, Lu J, Robertson ES. EBV essential antigen EBNA3C attenuates H2AX expression. J Virol. 2014; 88(7): 3776-88. JIF:4.7. ± Equal contribution.18

2013

Jha HC, Lu J, Saha A, Cai Q, Banerjee S, Prasad M, Robertson ES. EBNA3C-Mediated Regulation of Aurora Kinase B Contributes to Epstein-Barr Virus-Induced B-CellProliferation through Modulation of the Activities of the Retinoblastoma Protein and Apoptotic Caspases. J Virol. 2013; 87(22):12121-38. JIF:4.7.

Banerjee S, Lu J, Cai Q, Saha A, Jha HC, Dzeng RK, Robertson ES. The EBV latent antigen 3C inhibits apoptosis through targeted regulation of interferon regulatory factors 4 and 8. Plos Pathogens. 2013; 9(5), e1003314. JIF:8.0.

Jha HC±, Upadhyay SK±, Prasad M, Lu J, Cai Q, Saha A, Robertson ES. H2AX  phosphorylation is important for LANA mediated KSHV episome persistence. J Virol. 2013; 87(9):5255-69. JIF:4.7. ± Equal contribution

2012 and older

Srivastava P, Bhengraj AR, Jha HC, Vardhan H, Jha R, Singh LC, Salhan S, Mittal A. Differing Effects of Azithromycin and Doxycycline on Cytokines in Cells from Chlamydia Trachomatis-Infected Women. DNA Cell Biol. 2012; 31(3): 392-401. JIF:2.1.

Gao J, Cai Q, Lu J, Jha HC, Robertson ES. Upregulation of Cellular Bcl-2 by the KSHV Encoded RTA Promotes Virion Production. PLoS ONE. 2011; 6 (8): e23892. JIF:3.7.    

Jha HC, Srivastava P, Vardhan H, Singh LC, Bhengraj AR, Prasad J, Mittal A. Chlamydia pneumoniae heat shock protein 60 is associated with apoptotic signaling pathway in human atheromatous plaques of coronary artery disease patients. J Cardiol. 2011; 58(3):216-25. JIF:2.56.

Jha HC, Srivastava P, Prasad J, Mittal A. Chlamydia pneumoniae heat shock protein 60 enhances expression of ERK, TLR-4 and IL-8 in atheromatous plaques of coronary artery disease patients. Immunological Investigation. 2011; 40(2), 206-222. JIF:1.9.

Vardhan H, Bhengraj AR, Jha R, Srivastava P, Jha HC, Mittal A. Higher expression of ferritin protects Chlamydia trachomatis infected HeLa 229 cells from reactive oxygen species mediated cell death. Biochem Cell Biol. 2010; 88:1–8. JIF:2.9.

Jha HC, Divya A, Prasad J, Mittal A. Circulatory plasma inflammatory marker in male and female coronary artery disease patients. Heart & Lung: The Journal of Acute and Critical Care. 2010; 39(4), 296-303. JIF:1.3.

Jha HC, Mittal A. Sequencing of Chlamydia pneumoniae in coronary artery disease patients attending tertiary hospital in India. American Journal of Infection Control. 2010; Vol. 38 No. 6. JIF:2.3.

Jha HC, Mittal A. Why first degree relatives of coronary artery disease patients have   Chlamydia pneumoniae infection. International Journal of Cardiology. 2010, 144(3): e46-7. JIF:5.

Jha HC, Srivastava P, Divya A, Prasad J, Mittal A. Presence of Chlamydia pneumoniae is higher in aorta and coronary artery compared to carotid artery in coronary artery disease patients. APMIS. 2009; 117: 905–911. JIF:1.92.

Srivastava P, Jha HC, Salhan S, Mittal A. Azithromycin treatment modulates  cytokine production in Chlamydia trachomatis infected women. Basic & Clinical Pharmacology & Toxicology. 2009;104, 478–482. JIF:2.3.

Jha HC, Srivastava P, Sarkar R, Prasad J, Mittal A. Higher serum level of IL-8 and IL-4 in Chlamydia pneumoniae infected coronary artery disease patients may indicate disease pathogenesis. Mediators of Inflammation. 2009; 2009:561532. JIF:2.4.

Vardhan H, Dutta R, Vats V, Gupta R, Jha R, Jha HC, Srivastava P, Bhengraj AR, Mittal  A. Elevated IL-8 promotes cellular sustenance not the proliferation of Chlamydia trachomatis infected HeLa 229 cells. Mediators of Inflammation. 2009; 2009: 417658. JIF:2.4.

Jha HC, Mittal A. Coronary Artery Disease patient's first degree relatives may be at higher risk for atherosclerosis. International Journal of Cardiology 2009 Jul 10; 135 (3):408-9. JIF:5.

Jha HC, Srivastava P, Sarkar R, Prasad J, Mittal A. Chlamydia pneumoniae IgA and elevated level of IL-6 may synergize to accelerate coronary artery disease outcome. Journal of Cardiology. 2008; 52: 140-145. JIF: 2.56.

Srivastava P, Gupta R, Jha HC, Jha R, Bhengraj AR, Salhan S, Mittal A. Serovar specific immune responses to peptides of variable regions of Chlamydia Trachomatis Major Outer Membrane Protein in serovar D infected women. Clinical and Experimental Medicine. 2008; 8(4):207-15. JIF. 2.8.

Jha HC, Prasad J, Mittal A. High IgA seropositivity for combined Chlamydia pneumoniae, Helicobacter pylori infection and high sensitive C-reactive protein in Coronary Artery Disease patients in India can serve as atherosclerotic marker. Heart Vessels. 2008; 23: 390-396. JIF: 2.1.

Jha HC, Vardhan H, Gupta R, Verma R, Prasad J, Mittal A. Higher incidence of persistent chronic infection of Chlamydia pneumoniae among CAD patients in India is a cause of concern. BMC Infectious Diseases. 2007; 7:48. JIF: 2.56.

Abstract published in conference proceedings

Jha HC, Divya A, Prasad J, Mittal A. Coronary artery disease patient's first-degree relatives and atherosclerosis in India. Journal of Diabetes, April 2009, Pages: A228-A229. JIF:2.4.

Jha HC, Srivastava P, Prasad J, Mittal A. Evaluation of plasma circulatory markers, Chlamydia pneumoniae and High sensitive C-reactive protein in coronary artery Disease patient's. Atherosclerosis Supplements, June 2009 (Vol.10, Issue 2, Page e109). JIF:2.6.

Jha HC, Srivastava P, Prasad J, Mittal A. Coronary artery disease: Biomarkers in first- degree relatives. Atherosclerosis Supplements June 2009 (Vol. 10, Issue 2, Page e1558). JIF:2.6.

Commentary

Saini V, Knadpal M, and Jha HC. Association between Helicobacter pylori infection and incident risk of dementia: The AMI cohort Journal of the American Geriatrics Society. February 2024.

Mittal A, Jha HC, Prasad J. Chlamydia Pneumoniae and Associated Risk Factors in Coronary Artery Disease Patients in India. International Atherosclerosis Society. September 2008. JIF: NA.

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