With Live Captions (beta), spoken dialogue is turned into text and displayed in real time on your iPhone screen. You can more easily follow the audio in any app, such as FaceTime or Podcasts, and in live conversations around you. Live Captions is available on iPhone 11 and later when the primary language is set to English (U.S.) or English (Canada).

Do you use any third party or other type of backend service?

The initial connection and unique ID generation is made on our private server, when the two users are connected, the server is not in use anymore and all data(text, files or video stream) is transmitted directly from one user to another.

Also, no data is saved or goes through Bubble database.


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I created a new CTA (Beta) page for the purpose of sharing new regulatory information on my company's website. Can I embed the CTA as a text link as opposed to a CTA button? 


The context would be something like: "These 25 States are eligible for new incentives." Where the link "25 States" would trigger the CTA. Thanks in advance for your input!

In here select the "styles" tab on the left and set your text style to whatever you want and disable padding/set all the options to 0. In "background" set the background colour opacity to "0%" this will make the background transparent. You want no border and the corner radius to 0% too. Then set the hover styles to whatever you wish.

Yes, you can certainly embed a call-to-action (CTA) as a text link instead of using a CTA button. This approach can provide a more subtle and integrated way to direct users to specific content while maintaining the context of the text link. In your case, using a text link to trigger your new CTA page is a great idea.

If you have a Mac computer you can now sync your calls and texts to Cloze using iCloud instead of connecting to your iPhone. With this syncing option, you no longer need to connect over Wi-Fi or use a cable to sync your iPhone calls and texts with Cloze. And, you no longer have to enter your passcode each time a sync runs.

If you would like to automatically track WhatsApp calls and texts, the WhatsApp desktop app needs to be installed and running on your Mac. Once installed and running Cloze will track your calls and texts automatically.

If you want to stop backup of your texts, call history, and voicemail to your Google Account, you can stop sync. If you used Hangouts for text messages, you can still find your text messages in Gmail.

The Phone app is central to the iPhone experience, and it receives a big update with personalized Contact Posters, providing a new way for users to express themselves. Users can customize how they appear, bringing a completely new look to incoming calls, and choose beautiful treatments for photos or Memoji, as well as eye-catching typography and font colors. Contact Posters will also be available for third-party calling apps.


FaceTime calls also get more expressive with Reactions such as hearts, balloons, fireworks, laser beams, rain, and more. The new effects can be activated through simple gestures, and third-party video calling apps can take advantage of them as well.

The developer beta of iOS 17 is available to Apple Developer Program members at developer.apple.com starting today, and a public beta will be available next month at beta.apple.com. New software features will be available this fall as a free software update for iPhone Xs and later. For more information, visit apple.com/ios/ios-17-preview. Features are subject to change. Some features may not be available in all regions, all languages, or on all devices. For more information about availability, visit apple.com.

I took out my very old iPhone se (1st gen) and started using it again, it is supposed to be compatible with iOs 15. When I get text or email it vibrates very gently, like I can feel it if I'm holding it in my hand, but no notification sounds, no ringtone when I get a call.

DiRECT is the latest in a series of studies to test the 2008 Twin Cycle hypothesis. Research released in 2011 reported a dramatic fall in liver fat and a significant decrease in intra-pancreatic fat levels following 33 pounds of weight loss with recovery of some beta cell function in people with T2D. In 2016, scientists reported that maintaining a healthy weight for nine months after a period of weight loss assisted in beta cell recovery. The open-labeled, cluster-randomized controlled trial involved 306 participants from 49 primary care practices in Scotland and England between 2014 and 2017. Patients ranged in ages from 20 to 65, had a body mass between 27-45 kg/m 2, were not receiving insulin and with up to 6 years duration of T2D. Practices were randomly selected to offer participants one of two treatments, both of which had already been shown to be effective. DiRECT aimed to ascertain which treatment option was more effective.

WhatsApp already allows Android and iOS users to text unknown phone numbers without adding them to their contacts list. Now, the company has started testing the feature on the recently released WhatsApp beta for Windows 2.2342.6.0.

The beta update available on the Microsoft Store brings a new option to initiate conversations with unsaved phone numbers. As per WABetaInfo, you can go to the "New Chat" screen in the WhatsApp Windows beta app where you'll find an option called "Phone Number."

The feature is currently available to a limited number of testers running the latest beta update and it will be available to more testers in the coming future. It was introduced earlier this year on mobile devices and allows users to quickly initiate conversations with people they don't know so well.

The feature can be used in situations, for instance, when you need to have a quick chat with a delivery person. Before that, WhatsApp allowed users to text unknown phone numbers by creating "wa.me" URLs using their web browsers.

Another mechanism of -glucan action is mediated via the activated complement receptor 3 (CR3, also known as CD11b/CD18), which is found on natural killer (NK) cells, neutrophils, and lymphocytes. This pathway is responsible for opsonic recognition of -glucans leading to phagocytosis and reactor cells lysis. -glucans bind to the lectin domain of CR3 and prime it for binding to inactivated complement 3b (iC3b) on the surface of reactor cells. The reactor cells can be of any cell type including cancer cells tagged with monoclonal antibody and coated with iC3b. The -glucans-activated circulating cells such as the CR3 containing neutrophils will then trigger cell lysis on iC3b-coated tumor cells [28]. Similarly, majority of the human NK cells express CR3 and it was shown that opsonization of NK cells coated with iC3b leads to an increase in the lysis of the target. The beta chain of the CR3 molecule (CD18) rather than the alpha chain (CD11b) is responsible to the -glucan binding [51, 52].

We would like to thank Dr. Anita Chan (U. Alberta) for the English editing, Mr. Spencer Ng for the production of the graphic figures, the Edward Sai-Kim Hotung Paediatric Education & Research Fund, URC/CRCG Grants and Pau Kwong Wun Charitable Foundation for supporting the beta-glucan related works.

Quick question: is it possible to setup Sphinx to recognize any text and not just the predefined word sequence? I wonder if it would work if the grammar is replaced with intent recognition tool, like opennlp. Check -intent-toolkit

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (2.1M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

UFM1 is a member of the ubiquitin like protein family. While the enzymatic cascade of UFM1 conjugation has been elucidated in recent years, the biological function remains largely unknown. In this report we demonstrate that the recently identified C20orf116 [1], which we name UFM1-binding protein 1 containing a PCI domain (UFBP1), andCDK5RAP3 interact with UFM1. Components of the UFM1 conjugation pathway (UFM1, UFBP1, UFL1 and CDK5RAP3) are highly expressed in pancreatic islets of Langerhans and some other secretory tissues. Co-localization of UFM1 with UFBP1 in the endoplasmic reticulum (ER)depends on UFBP1. We demonstrate that ER stress, which is common in secretory cells, induces expression of Ufm1, Ufbp1 and Ufl1 in the beta-cell line INS-1E.siRNA-mediated Ufm1 or Ufbp1knockdown enhances apoptosis upon ER stress.Silencing the E3 enzyme UFL1, results in similar outcomes, suggesting that UFM1-UFBP1 conjugation is required to prevent ER stress-induced apoptosis. Together, our data suggest that UFM1-UFBP1participate in preventing ER stress-induced apoptosis in protein secretory cells.

The pancreatic beta cell is unique in its capacity to synthesize, store and secrete insulin with precise rates to cover the metabolic needs of the organism [7]. The fine-tuning of insulin synthesis, storage and secretion is regulated at many levels of gene expression, ranging from transcription, mRNA stability to translation and folding [8]. Microautophagic activity also plays a role in maintaining cellular hormone stores to optimal levels [9]. To fulfill this heavy task of insulin biosynthesis, the beta cell has a highly developed endoplasmic reticulum (ER). Optimal functioning of the ER is essential for proper protein folding and cell survival. Any disturbance in ER folding needs and capacity leads to ER stress and activation of the ER stress response (also called unfolded protein response) [10], [11], [12], [13]. The aim of this response is to restore ER homeostasis and at least three functionally distinct responses have been identified. First, up-regulation of ER chaperones to increase protein folding activity and to prevent protein aggregation [14]. Second, attenuation of global protein translation to reduce the load of newly synthesized proteins and prevent excessive accumulation of unfolded proteins [15], [16]. Finally, degradation of proteins misfolded in the ER, which is called ER-associated degradation (ERAD) [17]. Three ER stress transducers can be recognized: IRE1, ATF6 and PERK [15], [18], [19]. IRE1 induces Xbp1 splicing, which in turn, together with ATF6, induces transcription of chaperones (e.g. BiP), genes involved in ERAD and CHOP. In parallel, PERK activation upon ER stress increases eIF2 phosphorylation, which on the one hand inhibits protein translation and on the other hand activates transcription of chaperones, genes involved in ERAD and CHOP. When this ER stress response fails to restore ER homeostasis, apoptosis is triggered [20]. 17dc91bb1f

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