Visit Google Scholar for Dr. Choong-Gu Lee's complete publication record.

2025

• Ets1 acts as a negative regulator of peripherally induced regulatory T cell development. (Corresponding author) Manuscript in preparation

• Unraveling the interplay of cis- and trans-regulatory elements of IL-10. (Corresponding author) Manuscript in preparation

• Microbial butyrate enhances T follicular helper cell function to boost mucosal immunity. Manuscript under revision

• Micheliolide mitigates cancer cachexia through context-dependent modulation of the gut-immune axis. (Co-corresponding author) Manuscript submitted

• Jo SW*, Velankanni P*, Nhung DTC, Nguyen CHB, Jeon JY, Kim BR, Lee DH, Lee CG†, Park JS†. Chemical profiling and immune-stimulating activity of solvent fractions derived from dietary chlorella. J Microbiol Biotechnol. 2025 Jun 12:35:e2503021. (Co-corresponding author) IF 3.1, JCR 44.4%

2024

• Hong S*, Nguyen BN*, Min H, Youn HY, Choi S, Hitayezu E, Cha KH, Park Y, Lee CG, Yoo GH†, Kim M†. Host-specific effects of Eubacterium species on Rg3-mediated modulation of osteosarcopenia in a genetically diverse mouse population. Microbiome. 2024 Dec 02; 12:251. IF 13.8, JCR 4.7%

• Nguyen BN, Hong S, Choi S, Lee CG†, Yoo GH†, Kim M†. Dexamethasone-induced muscle atrophy and bone loss in six genetically diverse collaborative cross founder strains demonstrates phenotypic variability by Rg3 treatment. J Ginseng Res. 2024 May;48(3):310-322. (Co-corresponding author) IF 6.8, JCR 1.2% 

2023

• Lee CG*, Cha KH*, Kim GC, Im SH†, Kwon HK†. Exploring Probiotic Effector Molecules and Their Mode of Action in Gut-Immune Interactions. FEMS Microbiol Rev. 2023 Jul 5;47(4):fuad046. (Co-first author) IF 11.3, JCR 9.3%

• Velankanni P, Go SH, Jin JB, Park JS, Park S, Lee SB, Kwon HK, Pan CH†, Cha KH†, Lee CG†. Chlorella vulgaris modulates gut microbiota and induces regulatory T Cells to alleviate colitis in mice. Nutrients. 2023 Jul 25; 15(15): 3293. (Co-corresponding author) IF 5.9, JCR 18.7%

• Yoon JH*, Do JS*, Velankanni P*, Lee CG†, Kwon HK†. Gut microbial metabolites on host immune responses in health and disease. Immune Netw. 2023  Feb 24; 23:e6. (Co-corresponding author) IF 6.0, JCR 29.5%

2022

• Mabwi H, Lee HJ, Hitayezu E, Mauliasari I, Pan CH, Mwaikono Kilaza, Komba E, Lee CG†, Cha KH†. Emodin modulates gut microbial community and triggers intestinal immunity. J Sci Food Agric. 2022 Sep 11;103(3):1273-1282. (Co-corresponding author) IF 4.1, JCR 18.1%

2021

• Kang H*, Kim GC*, Lee CG*, Park S, Sharma G, Verma R, Im SH†, Kwon HK†. Probiotics-derived metabolite ameliorates skin allergy by promoting differentiation of FOXP3+ regulatory T cells. J Allergy Clin Immunol. 2021 Apr;147(4):1517-1521. (Co-first author) IF 14.29, JCR 5.357% 

• Nam J, Seol DW, Lee CG, Wee G†, Yang S†, Pan CH†. Obtusifolin, an anthraquinone extracted from Senna Obtusifolia (L.) H.S.Irwin & Barneby, reduces inflammation in a mouse osteoarthritis model.  Pharmaceuticals. 2021 Mar 10;14(3):249. IF 5.863, JCR 13.587%

• Han SJ, Jun J, Eyun SI†, Lee CG†, Jeon J†, Pan CH†. Schisandrol A suppresses catabolic factor expression by blocking NF-κB signaling in osteoarthritis. Pharmaceuticals. 2021 Mar 8;14(3):241. (Co-corresponding author) IF 5.863, JCR 13.587%

2020

• Kim GC, Lee CG, Verma R, Rudra D, Kim T, Kang K, Nam JH, Kim Y, Im SH, Kwon HK. ETS1 suppresses tumorigenesis of human breast cancer via trans-activation of canonical tumor suppressor genes. Front Oncol. 2020 May 14;10:642. IF 6.244, JCR 25.413%

• Kang LJ, Oh E, Cho C, Kwon HK, Lee CG, Jeon J, Lee H, Choi S, Han SJ, Nam J, Song CU, Jung H, Kim HY, Park EJ, Choi EJ, Kim J, Eyun SI, Yang S. 3’-Sialyllactose prebiotics prevents skin inflammation via regulatory T cell differentiation in atopic dermatitis mouse models. Sci Rep. 2020 Mar 27;10(1):5603. IF 4.380, JCR 22.917%

2019

• Lee CG*, Kwon HK*, Kang H*, Kim Y, Nam J, Won Y, Park S, Kim T, Kang K, Rudra D, Jun CD, Park Z, Im SH. Ets1 suppresses atopic dermatitis by suppressing pathogenic T cell responses. JCI Insight. 2019 Mar 7;4(5):e124202. (Co-first author) IF 6.205, JCR 9.712%

2018

• Kim C, Lee CG, Jung JY, Ghosh A, Hasan S, Kang H, Lee C, Kim GC, Rudra D, Suh CH, Im SH. Ets1 suppresses T follicular helper type 2 cell differentiation to halt the onset of Systemic Lupus Erythematosus. Immunity. 2018 Dec 18;49(6):1034-1048.e8. IF 21.522, JCR 1.582%

• Kim GC, Kwon HK, Lee CG, Verma R, Rudra D, Kim T, Kang K, Nam JH, Kim Y, Im SH. Upregulation of Ets1 expression by NFATc2 and NFKB1/RELA promotes breast cancer cell invasiveness. Oncogenesis. 2018 Nov 23;7(11):91. IF 5.995, JCR 14.130%

• Verma R, Lee C, Jeun EJ, Yi J, Kim KS, Ghosh A, Byun S, Lee CG, Kang HJ, Kim GC, Jun CD, Jan G, Suh CH, Jung JY, Sprent J, Rudra D, De Castro C, Molinaro A, Surh CD, Im SH. Cell surface polysaccharides of Bifidobacterium bifidum induce the generation of Foxp3+ regulatory T Cells. Sci Immunol. 2018 Oct 19;3(28):eaat6975. IF 10.551, JCR 6.013%

• Hwang W*, Lee CG*, Lee C, Verna R, Rudra D, Park Z, Im SH. Locus-specific reversible DNA methylation regulates transient IL-10 expression in Th1 cells. J Immunol. 2018 Mar 1;200(5):1865-1875. (Co-first author) IF 4.539, JCR 24.839%

2017

• Chae CS, Kim GC, Park ES, Lee CG, Verma R, Cho HL, Jun CD, Yoo YJ Im SH. NFAT1 regulates systemic autoimmunity through the modulation of a dendritic cell property. J Immunol. 2017 Nov 1;199(9):3051-3062. IF 4.539, JCR 24.839%

• Park S*, Lee S*, Lee CG*, Hong H, Lee JS, Kim YM, Park GY, Lee SB, Hwang D, Choi YS, Fryer JD, Im SH†, Lee SW† and Lee Y†. Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5. Nat Commun. 2017 Jul 12;8:16037. (Co-first author) IF 12.353, JCR 3.906%

2014

• So JS, Kim GC, Song M, Lee CG, Park E, Kim HJ, Kim YS, Jun CD, Im SH. 6-Methoxyflavone inhibits NFAT translocation into the nucleus and suppresses T cell activation. J Immunol. 2014 Sep 15;193(6):2772-83. IF 5.362, JCR 16.319%

• Ryu JH, Chae CS, Kwak JS, Oh H, Shin Y, Huh YH, Lee CG, Park YW, Chun CH, Kim YM, Im SH†, Chun JS†. Hypoxia-inducible factor-2α is an essential catabolic regulator of inflammatory rheumatoid arthritis. PLoS Biol. 2014 Jun 10;12(6):e1001881. IF 11.771, JCR 0.588%

2012

• Lee CG, Kwon HK, Sahoo A, Hwang W, So JS, Hwang JS, Chae CS, Kim GC, Kim JE, So HS, Hwang ES, Grenningloh R, Ho IC, Im SH. Interaction of Ets-1 with HDAC1 represses IL-10 gene expression in Th1 cells. J Immunol. 2012 Mar 1;188(5):2244-53. (First author) IF 5.788, JCR 14.029%

2011

• Sahoo A, Lee CG, Jash A, Son JS, Kim G, Kwon HK, So JS, Im SH. Stat6 and c-Jun Mediate Th2 Cell-Specific IL-24 Gene Expression. J Immunol. 2011 Apr 1;186(7):4098-109. IF 5.788, JCR 14.029%

• Lee CG, Hwang W, Maeng KE, Kwon HK, So JS, Sahoo A, Lee SH, Park ZY, Im SH. IRF4 regulates IL-10 gene expression in CD4+ T cells through differential nuclear translocation. Cell Immunol. 2011 Mar 4;268(2):97-104. (First author) IF 2.575, JCR 56.343%

• Kwon HK, Hwang JS, Lee CG, So JS, Sahoo A, Im CR, Jeon WK, Ko BS, Lee SH, Park ZY, Im SH. Cinnamon extract suppresses experimental colitis through modulation of antigen-presenting cells. World J Gastroenterol. 2011 Feb 28;17(8):976-86. IF 2.471, JCR 42.568%

• So JS, Song MK, Kwon HK, Lee CG, Chae CS, Sahoo A, Jash A, Lee SH, Park ZY, Im SH. Lactobacillus casei enhances type II collagen/glucosamine-mediated suppression of inflammatory responses in experimental osteoarthritis. Life Sci. 2011 Feb 14;88(7-8):358-66. IF 2.527, JCR 40.805%

• Jash A, Kwon HK, Sahoo A, Lee CG, So JS, Kim J, Oh YK, Kim YB, Im SH. Topical application of porcine placenta extract inhibits the progression of experimental contact hypersensitivity. J Ethnopharmacol. 2011 Jan 27;133(2):654-62. IF 3.014, JCR 15.909%

2010

• Lee CG, Kwon HK, Ryu JH, Kang SJ, Im CR, Kim JI, Im SH. Abalone visceral extracts inhibit tumor growth and metastasis by modulating Cox-2 levels and CD8+ T cell activity. BMC Complement Altern Med. 2010 Oct 20;10:60. (First author) IF 2.195, JCR 26.190%

• Kwon HK, Hwang JS, So JS, Lee CG, Sahoo A, Ryu JH, Jeon WK, Ko BS, Lee SH, Park ZY, Im SH. Cinnamon extract induces tumor cell death through inhibition of NFkappaB and AP1. BMC Cancer. 2010 Jul 24;10:392. IF 3.153, JCR 35.405%

• Kwon HK, Lee CG, So JS, Chae CS, Hwang JS, Sahoo A, Nam JH, Rhee JH, Hwang KC, Im SH. Generation of regulatory dendritic cells and CD4+Foxp3+ T cells by probiotics administration suppresses immune disorders. Proc Natl Acad Sci USA. 2010 Feb 2;107(5):2159-64. IF 9.771, JCR 4.237%

2009

• Lee CG*, Sahoo A*, Im SH. Epigenetic regulation of cytokine gene expression in T lymphocytes. Yonsei Med J. 2009 Jun 30;50(3):322-30. (Co-first author) IF 0.772, JCR 65.790%

• Kwon HK, Jeon WK, Hwang JS, Lee CG, So JS, Park JA, Ko BS, SH Im. Cinnamon extract suppresses tumor progression by modulating angiogenesis and the effector function of CD8(+) T cells. Cancer Lett. 2009 Jun 18;278(2):174-182. IF 3.741, JCR 31.020%

• Lee CG, Kang KH, So JS, Kwon HK, Son JS, Song MK, Sahoo A, Yi HJ, Hwang KC, Matsuyama T, Yui K, Im SH. A distal cis-regulatory element, CNS-9, controls NFAT1 and IRF4-mediated IL-10 gene activation in T helper cells. Mol Immunol. 2009 Feb;46(4):613-21. (First author) IF 3.555, JCR 28.510%

2008

• So JS, Lee CG, Kwon HK, Yi HJ, Chae CS, Park JA, Hwang KC, Im SH. Lactobacillus casei potentiate induction of oral tolerance in experimental arthritis. Mol Immunol. 2008 Nov;46(1):172-80. IF 3.742, JCR 25.630%

• Yi HJ, Lee CG, Kwon HK, So JS, Sahoo A, Hwang JS, Jash A, Hwang KC, Im SH. Defect in TCR-CD3zeta signaling mediates T cell hypo-responsiveness in mesenteric lymph node. Mol Immunol. 2008 Aug;45(14):3748-55. IF 3.742, JCR 25.630%

• Kwon HK, So JS, Lee CG, Sahoo A, Yi HJ, Park JN, Lim SY, Hwang KC, Jun CD, Chun JS, Im SH. Foxp3 induces IL-4 gene silencing by affecting nuclear translocation of NFκB and chromatin structure. Mol Immunol. 2008 Jun;45(11):3205-12. IF 3.742, JCR 25.630%

• So JS, Kwon HK, Lee CG, Yi HJ, Park JA, Lim SY, Hwang KC, Jeon YH, Im SH. Lactobacillus casei suppresses experimental arthritis by down-regulating T helper 1 effector functions. Mol Immunol. 2008 May;45(9):2690-9. IF 3.742, JCR 25.630%