Yu, Y.S., Kim, I.S., Baek,S.H., (2025) Decoding the Dual Role of Autophagy in Cancer through Transcriptional and Epigenetic Regulation. FEBS Lett., 599, 2237–2249.
Jang, J. †, Ahn, M. †, Jeong, J., Lee E., Park, M., Kim, Ok., Joo, Seul., Maeng, Han., Hong, I., Oh, B., Kim*, I.S., Kim*, H.J., Jung*, Y.J., (2025) Systemic inflammation–induced adipose tissue remodeling drives psoriasis exacerbation in obesity through epigenetic and immunometabolic dysregulation. Theranostics, 15(16): 8639-8657 (†co-first author, *co-corresponding author).
Ahn, J†, Kim, S.†, Kim, C.R.†, Kim, J.M., Choi, Y.H., Jeon, Y., Na, Y., Kim, J., Okada, Y., Lee, H., Kim, I.S.*, Kim, J.K.*, Koo, B.*, and Baek,S.H.*, (2024) The epigenetic regulator PHF16 suppresses YAP/TAZ activity in regenerative crypt stem cells, allowing return to the homeostatic state. Developmental Cell, 59, 1-17. (†co-first author, *co-corresponding author).
Kim, I.S, (2024) DNA Barcoding Technology for Lineage Recording and Tracing to Resolve Cell Fate Determination, Cells 13(1), 27.
Kim, I.S.†*, Kang, C.K.†, Lee, S.J.†, Lee, C.†, Kim, M., Seo, C., Kim, G., Lee, S., Kim, Y., Chang, E., Jung, J., Song, K., Choe, P.G., Park, W.B., Kim, E.S., Kim, H.B., Kim, N.J., Oh, M., Lee, J., Shin, H.M.*, Kim, H.*, (2023) Tracking Antigen-Specific TCR Clonotypes in SARS-CoV-2 Infection Reveals Distinct Severity Trajectories. Journal of Medical Virology 95:e29199. (†co-first author, *co-corresponding author)
Kim, I.S., (2023) Single-Cell Molecular Barcoding to Decode Multimodal Information Defining Cell States. Molecules and Cells 46 (2): 74–85.
Kang, C.K, Kim, M., Park, S., Kim, Y., Lee, C.M., Choe, P.G., Park, W.B., Kim, N.J., Kim, M., Lee, S., Kim, I.S., Lee, C., Shin, H.M., Kim, H., Oh, M., (2023). Comparable Humoral and Cellular Immunity against Omicron Variant BA.4/5 of Once-Boosted BA.1/2 Convalescents and Twice-Boosted COVID-19-Naïve Individuals. Journal of Medical Virology 95 (2): e28558.
Kang, C.K.†, Kim, M.†, Hong, J.†, Kim, G., Lee, S., Chang, E., Choe, P.G., Kim, N.J., Kim, I.S., Seo, J.Y., Song, D., Lee, D., Shin, H.M., Kim, Y., Lee, C.*, Park, W.B *, Kim, H.*, Oh, M., (2022) Distinct immune response at 1 year post-COVID-19 according to disease severity. Front. Immunol., 21;13:830433.
Kang, C.K., Kim, M., Lee, S., Kim, G., Choe, P.G., Park, W.B., Kim, N.J., Lee, C.-H., Kim, I.S., Jung, K., Lee, D.S., Shin, H.M., Kim, H.R., Oh, M.D., (2021) Longitudinal Analysis of Human Memory T-Cell Response according to the Severity of Illness up to 8 Months after SARS-CoV-2 Infection. J. Infect. Dis., 224 (1): 39–48.
Yu, Y.S., Shin, H-J.R., Kim, D., Baek, S.A., Choi, S.A., Ahn, H., Shamim, A., Kim, J., Kim, I.S., Kim, K.K., Won, K., Baek, S.H., (2020) Pontin Arginine Methylation by CARM1 Is Crucial for Epigenetic Regulation of Autophagy. Nature Comm., 11, 6297.
Kim, I.S.†, Wu, J.†, Rahme, G.J.†, Battaglia, S., Dixit, A., Gaskell, E., Chen, H., Pinello, L., and Bernstein, B.E. (2020). Parallel Single-Cell RNA-Seq and Genetic Recording Reveals Lineage Decisions in Developing Embryoid Bodies. Cell Reports, 33, 108222. (†co-first author)
Lee, I.K., Song, H., Kim, H., Kim, I.S., Tran, N. L., Kim, S., Oh, S. J.*, Lee, J. M.*, (2020) RORα Regulates Cholesterol Metabolism of CD8+ T Cell for Anti-Cancer Immunity. Cancers, 12 (7):1733
Brumbaugh, J.*, Kim, I.S.*, Ji, F., Huebner, A., Di Stefano, B., Schwarz, B.A., Charlton, J., Coffey, A., Choi, J., Walsh, R.M., Schindler, J.W., Anselmo, A., Meissner, A., Sadreyev, R.I., Bernstein, B.E., Hock, H., and Hochedlinger, K. (2019) Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site- specific histone methylation in vitro and in vivo. Nature Cell Biology, 21, 1449–1461. (*co-first author)
Oh, S.K., Kim, D., Kim, K., Boo, K., Yu, Y.S., Kim, I.S., Jeon, Y., Im, S.K., Lee, S.H., Lee, J.M., Ko, Y.H., Lee, H., Park, D., Fang, S., and Baek, S.H. (2019) RORα Is Crucial for Attenuated Inflammatory Response to Maintain Intestinal Homeostasis. PNAS, 116 (42): 21140-21149.
Lee, M.K.*, Kim, I.S.*, Park, K.C., Baek, S.H., and Kim, K.I. (2018) Mitosis-specific Phosphorylation of Mis18a by Aurora B Kinase Enhances Kinetochore Recruitment of Polo-like Kinase 1. Oncotarget, 9, 1563-1576. (*co-first author)
Shin, D.G.*, Kim, I.S.*, Lee, J.M., Shin, S.Y., Lee, J.H., Baek, S.H.†, and Cho, K.H.† (2014) The hidden switches underlying RORα-mediated circuits that critically regulate uncontrolled cell proliferation. J Mol Cell Biol., 6 (4): 338-48. (*co-first author, †co-corresponding author)
Kim, I.S., Lee, M.K., Park, J.H., Jeon, R., Baek, S.H., and Kim, K.I. (2014) βTrCP-mediated ubiquitylation regulates protein stability of Mis18β in a cell cycle-dependent manner. Biochem. Biophys. Res. Commun., 443 (1): 62-7
Kim, I.S., Lee, M.K., Park, K.C., Jeon, Y., Park, J.H., Hwang, E.J., Jeon, T.I., Ko, S.Y., Lee, H., Baek, S.H.*, and Kim, K.I.* (2012) Roles of Mis18a in Epigenetic Regulation of Centromeric Chromatin and CENP-A Loading. Molecular Cell, 46, 260-273 (*co-corresponding author)
Lee, J.M., Lee, J.S., Kim, H.K., Kim, K.K., Park, H.J., Kim, J.Y., Lee, S.H., Kim, I.S., Kim, J.M., Lee, M.K., Chung, C.H., Seo, S.B., Yoon, J.B., Ko, E.Y., Noh, D.Y., Kim, K.I., Kim, K.K., and Baek, S.H. (2012) EZH2 Generates a Methyl Degron That Is Recognized by the DCAF1/DDB1/CUL4 E3 Ubiquitin Ligase Complex. Molecular Cell, 48, 572-586
Kim, B.G., Nam, H.J., Pyo, K.E., Jang, M.J., Kim, I.S., Kim, D.H., Boo, K.J., Lee, S.H., Yoon, J.B., Baek, S.H., and Kim, J.H. (2011) Breast cancer metastasis suppressor 1 (BRMS1) is destabilized by the Cul3–SPOP E3 ubiquitin ligase complex. Biochem. Biophys. Res. Comm., 415, 720-726
Lee, J.S., Kim, Y., Kim, I.S., Kim, B., Choi, H.J., Lee, J.M., Shin, H-J.R., Kim, J.H., Kim, J.-Y., Seo, S.-B., Lee, H., Binda, O., Gozani, O., Semenza, G.L., Kim, M., Kim, K.I., Hwang, D.H., and Baek, S.H. (2010) Negative Regulation of Hypoxic Responses via Induced Reptin Methylation. Molecular Cell, 39, 71-85
Lee, J.M., Kim, I.S., Kim, H.K., Lee, J.S., Kim, K.K., Yim, H.Y., Jeong, J.Y., Kim, J.H., Kim, J.Y., Lee, H.N, Seo, S.B., Kim, H.G., Rosenfeld, M.G., Kim, K.I., and Baek, S.H. (2010) RORalpha Attenuates Wnt/b-Catenin Signaling by PKCa-dependent Phosphorylation in Colon Cancer. Molecular Cell, 37, 183-195.
Kim, I.S., and Baek, S.H. (2010) Mouse Models for Breast Cancer Metastasis. Biochem. Biophys. Res. Comm., 394, 443-447
Kim, J.H., Choi, H.J., Kim, B., Kim, M.H., Lee, J.M., Kim, I.S., Lee, M.H., Choi, S.J., Kim, K.I., Kim, S.I., Chung, C.H., and Baek, S.H. (2006) Roles of SUMOylation of a Reptin chromatin remodeling complex in cancer metastasis. Nature Cell Biology, 8, 631-639.