Designing metallic, polymeric, and hydrogel-based biomaterials and integrating tissue engineering strategies to modulate cell–material interactions for bone, cartilage, and musculoskeletal tissue repair and regeneration.

• Biodegradable metallic and polymeric biomaterials

• Bone and osteochondral tissue regeneration

• Injectable hydrogels and tissue adhesives

• Meniscus repair and regeneration

• Cell-biomaterial interactions 

Developing functional biomaterials responsive to light, heat, magnetic fields, and other physical stimuli to regulate material properties and cellular responses for tissue regeneration and rehabilitation.

• NIR-responsive photothermal biomaterials

• Photothermal nanocomposites and hydrogels

• Magnetic and magnetically responsive biomaterials

• Physical stimulation for regulating cellular responses

• Photothermal therapy for tissue regeneration

Integrating computer-aided design and engineering, 3D printing, and additive manufacturing to develop biodegradable and functional scaffolds, implants, and rehabilitation devices with controlled architectures.

• 3D-printed tissue engineering scaffolds

• Porous biodegradable implant design

• Biodegradable magnesium- and zinc-based implants

• Additive manufacturing of functional polymer composites

• Patient-specific orthopedic implants and rehabilitation devices

Integrating microfluidics, 3D printing, biomaterials, and tissue engineering to develop biomimetic in vitro models and biochips for investigating cell–material interactions, biological responses, drug screening, and biomedical sensing.

• Bone and osteochondral tissue-on-chip

• Microfluidic biochips

• In vitro platforms for biomaterial evaluation

• Drug screening and biological response evaluation

• Microfluidic biomedical detection and biosensing