Curriculum Vitae
Huisuk Yang, 2021
Nationality: Republic of Korea
Degree: Ph.D
Affiliation: JUVIC Inc.
E-mail: hsyang@juvicbio.com
Telephone: +82-10-8705-8384
Address: #208, Digital-ro 272, Guro-gu, Seoul 08389, Korea
Education
Ph.D in Department of Biotechnology Sep.2011 - Feb.2018
Yonsei University, Republic of Korea
Advisor: Prof. Hyungil Jung
B.S. in Mechanical Engineering
B.S. in Bioengineering & Biotechnology Mar.2006 - Aug.2011
Yonsei University, Republic of Korea
Visiting Student Program Jun.2008 - Jul.2008
University of California Los Angeles, U.S.A.
Experiences
JUVIC Inc. Oct.2015 - Present
CEO
Developement of micrnoeedle-based drug delivery systems
Establishment of pharmaceutical micrnoeedle manufacturing GMP site
homepage: http://juvicbio.com/
Raphas Co. Ltd. Sep.2011 - Mar.2012
Internship
Develeopement of cosmetic microneedle patches
Clinical trials of cosmetic microneedle products
Patented technical transfer
Publications
H. Yang, G. Kang, M. Jang, D. J. Um, J. Shin, H. Kim, J. Hong, H. Jung, H. Ahn, S. Gong, C. Lee, U. Jung, H. Jung*, "Development of Lidocaine-Loaded Dissolving Microneedle for Rapid and Ecient Local Anesthesia", Pharmaceutics, 2020, 12, 1067
M. Jang, S. Baek, G. Kang, H. Yang, S. Kim,H. Jung*, "Dissolving Microneedle with High Molecular Weight Hyaluronic Acid to improve skin wrinkles, dermal density and elasticity", International Journal of Cosmetic Science, 2020, 42, 302
S. Kim, H. Yang, J. Eum, Y. Ma, S. F. Lahiji, H. Jung*, "Implantable Powder-carrying Microneedles for Transdermal Delivery of High-Dose Insulin with Enhanced Activity", Biomaterials, 2020, 232, 119733
S. Kim, J. Eum, H. Yang, H. Jung*, "Transdermal Finasteride Delivery via Powder-carrying Microneedles with Diffusion Enhancer for the Treatment of Androgenetic Alopecia", Journal of Controlled Release, 2019, 316, 1
G. Kang, S. Kim, H. Yang, M. Jang, L. Chiang, J. H. Baek, J. H. Ryu, G. W. Choi, H. Jung*, "Combinatorial application of dissolving microneedle patch and cream for improvement of skin wrinkles, dermal density, elasticity, and hydration", Journal of Cosmetic Dermatology, 2019, 1, 1083
H. Yang, S. Kim, M. Jang, H. Kim, S. Lee, Y. Kim, Y. A. Eom, G. Kang, L. Chiang, J. H. Baek, J. H. Ryu, Y. E. Lee, J. Koh, H. Jung*, "Two‐phase delivery using a horse oil and adenosine‐loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement", Journal of Cosmetic Dermatology, 2019, 18, 936
C. Lee, H. Kim, S. Kim, S. F. Lahiji, N. Ha, H. Yang, G. Kang, H. Y. T. Nguyen, Y. Kim, M. Choi, N. Cho*, H. Jung*, "Comparative Study of Two Droplet-based Dissolving Microneedle Fabrication Methods for Skin Vaccination", Advanced Healthcare Materials, 2018, 7, 1701381
G. Kang, T. N. T. Tu, S. Kim, H. Yang, M. Jang, D. Jo, J. Rye, J. Baek, H. Jung*, "Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration", International Journal of Cosmetic Science, 2018, 40, 199
C. Lee, Y. A. Eom, H. Yang, M. Jang, S. U. Jung, Y. O. Park, S. E. Lee, H. Jung*, "Skin Barrier Restoration and Moisturization using Horse Oil-loaded Dissolving Microneedle Patches Short title: Skin Barrier Restoration using Dissolving Microneedles", Skin Pharmacology and Physiology, 2018, 31, 163
S. F. Lahiji, S. H. Seo, S. Kim, M. Dangol, J. Shim, C. G. Li, Y. Ma, C. Lee, G. Kang, H. Yang, K. Choi, H. Jung*, "Transcutaneous implantation of valproic acid-encapsulated dissolving microneedles induces hair regrowth", Biomaterials, 2018, 167, 69
S. F. Lahiji, Y. Jang, Y. Ma, M. Dangol, H. Yang, M. Jang, H. Jung*, "Effects of dissolving microneedle fabrication parameters on the activity of encapsulated lysozyme", European Journal of Pharmaceutical Sciences, 2018, 117, 290
S. F. Lahiji, Y. Jang, I. Huh, H. Yang, M. Jang, H. Jung*, "Exendin-4-encapsulated dissolving microneedles arrays for efficient treatment of type 2 diabetes", Scientific Reports, 2018, 8, 1170
I. Huh, S. Kim, H. Yang, M. Jang, G. Kang, H. Jung*, "Effects of two droplet-based dissolving microneedle manufacturing methods on the activity of encapsulated epidermal growth factor and ascrobic acid", European Journal of Pharmaceutical Sciences, 2018, 114, 285
S. Kim, J. Lee, S. F. Lahiji, S. Kim, I. Huh, Y. Ma, H. Yang, G. Kang, H. Jung*, "Physicochemical study of ascorbic acid 2-glucoside loaded hyaluronic acid dissolving microneedles irradiated by electron beam and gamma ray", Carbohydrate Polymers, 2018, 180, 297
H. Yang, S. Kim, G. Kang, S. F. Lahiji, M. Jang, Y. M. Kim, J. Kim, S. Cho, H. Jung*, "Centrifugal Lithography: Self-Shaping of Polymer Microstructures Encapsulating Biopharmaceutics by Centrifuging Polymer Drops", Advanced Healthcare Materials, 2017, 6, 1700326
S. Kim, M. Dangol, G. Kang, S. F. Lahiji, H. Yang, M. Jang, Y. Ma, C. Li, S. G. Lee, C. H. Kim, Y. W. Choi, S. J. Kim, J. H. Ryu, J. H. Baek, J. Koh, H. Jung*, "Enhanced transdermal delivery by combined application of dissolving microneedle patch on serum treated skin", Molecular Pharmaceutics, 2017, 14, 2024
S. Kim, M. Park, H. Yang, M. Dangol, S. F. Lahiji, I. Huh, M. Kim, J. Lee, J. Son*, H. Jung*, “Development of a quantitative method for active epidermal growth factor extracted from dissolving microneedle by solid phase extraction and liquid chromatography electrospray ionization mass spectrometry”, Journal of Pharmaceutical and Biomedical Analysis, 2016, 131, 297
H. Yang, C. Lee, S. Kim, M. Kim, H. Kang, N. Kim, S. An, J. Koh, H. Jung*, “Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study”, International Journal of Cosmetic Science, 2016, 38, 375
M. Dangol, H. Yang, C. G. Li, S. F. Lahiji, S. Kim, Y. Ma, H. Jung*, “Innovative polymeric system (IPS) for solvent-free lipophilic drug transdermal delivery via dissolving microneedles”, Journal of Controlled Release, 2016, 223, 118
M. Kim, H. Yang, S. Kim, C. Lee, H. Jung*, “The Troy Microneedle: A Rapidly Separating, Dissolving Microneedle Formed by Cyclic Contact and Drying on the Pillar (CCDP)”, PLoS ONE, 2015, 10, 8
S. Kim, H. Yang, M. Kim, J. H. Baek, S. J. Kim, S. M. An, J. S. Koh, H. Jung*, “4-n-butylresorcinol dissolving microneedle patch for skin depigmentation: a randomized, double-blind, placebo-controlled trial”, Journal of Cosmetic Dermatology, 2015,15, 16
H. Yang, S. Kim, I. Huh, S. Kim, S. F. Lahiji, M. Kim, H. Jung*, “Rapid implantation of dissolving microneedles on an electrospun pillar array”, Biomaterials, 2015, 64, 70
M. Kim, H. Yang, H. Kim, H. Jung, H. Jung*, “Novel cosmetic patches for wrinkle improvement: retinyl retinoate- and ascorbic acid-loaded dissolving microneedles”, International Journal of Cosmetic Science, 2014, 36, 207
S. G. Lee, J. H. Jeong, K. M. Lee, K. H. Jeong, H. Yang, M. Kim, H. Jung*, S. Lee, Y. W. Choi*, “Nanostructured lipid carrirer-loaded hyaluronic acid microneedles for controlled dermal delivery of a lipophilic molecule”, International Journal of Nanomedicine, 2013, 9, 289
J. D. Kim, M. Kim, H. Yang, K. Lee, H. Jung*, “Droplet-born air blowing: Novel dissolving microneedle fabrication”, Journal of Controlled Release, 2013, 170, 430
Issued Patents
KR 10-2198437, Shooting microstructures and applicator for the same, 2020
KR 10-2186163, Microstructures patch for multi-function, 2020
KR 10-2175312, Microstructure for transdermal delivery, 2020
KR 10-2175310, Shooting microstructures and Applicator for the same , 2020
CN ZL201780023330.4, Rotation assembler and centrifugal separator having the same, 2020
KR 10-2174568, Stamp type microstructure applicator, 2019
KR 10-2038751, Microneedle array with complex formulation and method for manufacturing the same, 2019
EP 2995342, Method for manufacturinf mircostructure using centrifugal force and microstructure manufactured by same, 2019
US 10441545, Microcellular microstructure and method for manufacturing same, 2019
JP 6626221, Rotation assembler and centrifugal separator having the same, 2019
JP 6622818, Microcellular microstructure and method for manufacturing same, 2019
KR 10-1935378, Rotation assembler and apparatus for manufacturing microstructure having the same, 2018
KR 10-1853308, Micro-room microstructure and method for fabricating thereof, 2018
KR 10-1827739, Micro-room microstructure and method for fabricating thereof, 2018
US 9943674, Microstructure-based drug delivery system comprising microporous structure, 2018
US 9974936, Method for manufacturing microstructure using negative pressure and microstructure manufactured thereor, 2018
CN ZL201480025446.8, Method for manufacturinf mircostructure using centrifugal force and microstructure manufactured by same, 2018
US 10245423, Method for manufacturinf mircostructure using centrifugal force and microstructure manufactured by same, 2018
KR 10-1703312, Microstructure-based drug delivery systems comprising microporous Structure , 2017
KR 10-1754309, Methods for preparing microstructures using centrifugal force and microstructures prepared by the same, 2017
KR 10-1808066, Microstructure and method for fabricatinf thereof using liquefaction of solid, 2017
JP 6110562, Method for manufacturinf mircostructure using centrifugal force and microstructure manufactured by same, 2017
KR 10-1590172, Methods for preparing microstructures using centrifugal force and microstructures prepared by the same, 2016
KR 10-1488397, process for preparing microstructures by negative pressure and microstructures prepared by the same, 2015
Awards
Excellent Poster Presentation Award, 2017 The Korean Society for Biotechnology and Bioengineering
Best Research Award, 2017 Yonsei Brain Korea 21 PLUS
Best Research Award, 2016 Yonsei Brain Korea 21 PLUS
Excellent Prototype Award, 2015 Yonsei Tech Fair
Excellent Technology Transfer and Industrialization Technology Development Award, 2015 Yonsei Brain Korea 21 PLUS