Publications

1. Zhou B, Wang C, Putzel G, Hu J, Liu M, Wu F, Chen Y, Pironti A, Li H. An integrated strain-level analytic pipeline utilizing longitudinal metagenomic data. Microbiol Spectr. 2024 Nov 5;12(11):e0143124. doi: 10.1128/spectrum.01431-24. Epub 2024 Sep 23. PMID: 39311770; PMCID: PMC11542597. 

2. Wang C, Ahn J, Tarpey T, Yi SS, Hayes RB, Li H. A microbial causal mediation analytic tool for health disparity and applications in body mass index. Microbiome. 2023 Jul 27;11(1):164. doi: 10.1186/s40168-023-01608-9. PMID: 37496080; PMCID: PMC10373330. 

3. Zhou B, Li H. (2023) STEMSIM: a simulator of within-strain short-term evolutionary mutations for longitudinal metagenomic data, Bioinformatics.  

4. Shi Y, Li H, Wang C, Chen J, Jiang H, Shih YT, Zhang H, Song Y, Feng Y, Liu L. A flexible quasi-likelihood model for microbiome abundance count data. Stat Med. 2023 Nov 10;42(25):4632-4643. doi: 10.1002/sim.9880. Epub 2023 Aug 22. PMID: 37607718; PMCID: PMC11045296. 

5. Wang, B, Yao, L, Hu, J and Li, H, 2022. A New Algorithm for Convex Biclustering and Its Extension to the Compositional Data. Statistics in Bioscience. https://doi.org/10.1007/s12561-022-09356-4

6. Wang C, Segal LN, Hu J, Zhou B, Hayes R, Ahn J, Li H. Microbial Risk Score for Capturing Microbial Characteristics, Integrating Multi-omics Data, and Predicting Disease Risk. 2022. Microbiome. 10, Article number: 121

7.  He L, Wang C, Hu J, Gao Z, Falcone E, Holland SM, Blaser MJ, Li H. ARZIMM: A Novel Analytic Platform for the Inference of Microbial Interactions and Community Stability from Longitudinal Microbiome Study. Front Genet. 2022 Feb 25;13:777877. doi: 10.3389/fgene.2022.777877. PMID: 35281829; PMCID: PMC8914110.

8.  Wang C, Hu J, Blaser MJ, and Li H. (2021) Microbial trend analysis for common dynamic trend, group comparison and classification in longitudinal microbiome study, BMC Genomics. 22. Article number: 667

9.   Hu J, Wang C, Blaser B, and Li H. (2021) JointMM: joint modeling of zero-inflated longitudinal proportions and time-to-event data with application to a gut microbiome study. 2021 July 02.  Biometrics.

10.   Zhang H, Chen J, Feng Y, Wang C, Li H, Liu L. (2021) Mediation effect selection in high-dimensional and compositional microbiome data. Statistics in Medicine. 2021 Feb 20;40(4):885-896. doi: 10.1002/sim.8808. 

11.   Wang C, Hu J, Blaser MJ, Li H. (2020) Estimating and testing the microbial causal mediation effect with high-dimensional and compositional microbiome data. Bioinformatics. 2020 Jan 15;36(2):347-355. 

12.   Hu J, Koh H, He L*, Liu M, Blaser MJ, and Li H. (2018) A two-stage microbial association mapping framework with advanced FDR control. Microbiome. 2018 6:131

13.   Koh H, Livanos A, Blaser MJ, Li H. (2018) A highly adaptive microbiome-based survival analysis method. BMC Genomics. 201819:210

14.   Bokulich NA, Zhang Y*, Dillon M, Rideout JR, Bolyen E, Li H, Albert PS, Caporaso JG. (2018) q2-longitudinal: a QIIME 2 plugin for longitudinal and paired-sample analyses of microbiome data. mSystems. 2018 3(6):- (# 3520192)

15.   Koh H, Blaser MJ and Li H. (2017) A powerful microbiome-based association test and a microbial taxa discovery framework for comprehensive association mapping. Microbiome. 5:45.

16.   Zhang Y, Han SW, Cox LM, and Li H. (2017) A Multivariate Distance Based Test on Microbial Temporal Interaction Group Comparison. Genetic Epidemiology. Dec, 41(8):769-778.  

17.  Li H, Chen J. (2016)  Efficient unified rare variant association test by modeling the population genetic distribution in case-control studies. Genetic Epidemiology. 2016 Nov,40(7):579-590.

18.   Li X, Li H, Jin M, Goldberg JD. (2016) Likelihood Ratio and Score Tests on Testing Non-inferiority (and Equivalence) of Odds-ratio in Crossover Study. Statistics in Medicine.  Stat Med. 2016 Apr 19.

19.   Li H, Gail MH, Braithwaite RS, Gold HT, Walter D, Liu M, Gross CP, Makarov DV. (2014)   Are hospitals “keeping up with the Joneses”?: Assessing the spatial and temporal diffusion of the surgical robot. Health Care.  2014 Jul, 2(2):152-157.

20.  Li H, Gail MH. (2012)    Efficient Adaptively Weighted Analysis of Secondary Phenotypes in Case-control Genome-wide Association Studies. Human Heredity. 2012, 73(3):159-173.

21.  Li H, Gail MH. (2012)   Power of the Armitage Trend Test when Categories are based on Empirical Quantiles of Exposure. Statistics and Its Interface. 2012, 5(2): 237-251.

22.  Li H, Gail MH, Berndt S, Chatterjee N.  (2010) Using Cases from Genome-Wide Association Studies to Strengthen Inference on the Association between Single Nucleotide Polymorphisms and a Secondary Phenotype. Genetic Epidemiology. 2010 Jul, 34(5):427-33.

23.   Li H, Graubard B, Gail, MH.(2010) Covariate Adjustment and Ranking Methods to Identify Regions with High and Low Mortality Rates. Biometrics. 2010 Jun,66(2):613-620.

24.  Li H, Lahiri P. (2010) Adjusted Maximum Likelihood Method in the Small Area Estimation Problem. Journal of Multivariate Analysis. 2010 Apr, 101(4):882-892.

25.  Lahiri P, Li H. (2009) An adaptive hierarchical Bayes quality measurement plan. Applied Stochastic Models in Business and Industry. 2009, 25(4):468-477.

26.   Chatterjee S, Lahiri P, Li H.  (2008) Parametric Bootstrap Approximation to the Distribution of EBLUP and Related Prediction Intervals in Linear Mixed Models. The Annals of Statistics.  2008, 36(3):1221-1245.

Microbiome in Kidneys, Diabetes, Obesity, Weight Loss, and Nutrition

1.  Nazzal L, Francois F, Henderson N, Liu M, Li H, Koh H, Wang C, Gao Z, Perez G, Asplin J, Goldfarb D. Effect of antibiotic treatment on Oxalobacter formigenes colonization of the gut microbiome and urinary oxalate excretion. Scientific reports. 2021 11(1):16428- (# 5004452)

2.  Liu M, Devlin JC, Hu J, Volkova A, Battaglia TW, Ho M, Asplin JR, Byrd A, Loke P, Li H, Ruggles KV, Tsirigos A, Blaser MJ, Nazzal L. Microbial genetic and transcriptional contributions to oxalate degradation by the gut microbiota in health and disease. Elife. 2021 Mar 26;10:e63642. PMID: 33769280.

3.  PeBenito A, Nazzal L, Wang C, Li H, Jay M, Noya-Alarcon O, Contreras M, Lander O, Leach J, Dominguez-Bello MG, Blaser MJ. Comparative prevalence of Oxalobacter formigenes in three human populations. Scientific reports. 2019 9(1):574-574 (# 3610112)

4.   Schulfer AF, Schluter J, Zhang Y, Brown Q, Pathmasiri W, McRitchie S, Sumner S, Li H, Xavier JB, Blaser MJ. The impact of early-life sub-therapeutic antibiotic treatment (STAT) on excessive weight is robust despite transfer of intestinal microbes. ISME J. 2019 May, 13(5):1280-1292. 

5.   Zhang XS, Li J, Krautkramer KA, Badri M, Battaglia T, Borbet TC, Koh H, Ng S, Sibley RA, Li Y, et al. Antibiotic-induced acceleration of type 1 diabetes alters maturation of innate intestinal immunity. Elife. 2018 Jul 25, 7. pii: e37816. 

6.  Liu M, Koh H, Kurtz Z, Battaglia T, PeBenito A, Li H, Nazzal L, Blaser MJ (2017) Oxalobacter formigenes-associated host features and microbial community structures examined using the American Gut project. Microbiome. 2017, 5:45.  

7.  Alexandra Livanos, Shingo Yamanishi, Li H, Clive Wasserfall, Mark Atkinson, Martin Blaser. (2016) Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in NOD mice", Nature Microbiology. 2016 Aug 22, 1(11):16140.

8.  Bokulich NA, Chung J, Battaglia T, Henderson N, Jay M, Li H, Lieber A, Wu F, Perez-Perez  GI,  Chen Y, Schweizer W, Zheng X, Contreras M, Dominguez-Bello MG, Blaser MJ. (2016) Antibiotics, birth mode, and diet shape microbiome maturation during early life. Science Trans Medicine. 2016 Jun 15, 8(343)

9.  Mahana D, Kurtz ZD, Bokulich NA, Trent CM, Battaglia T, Chung J, Müller CL, Li H, Bonneau RA and Blaser MB. (2016) Antibiotic perturbation of the murine gut microbiome enhances the adiposity, insulin resistance, and liver disease associated with high-fat diet. Genome Medicine 2016 Apr 27, 8(1):48.

10.  Nobel YR, Cox LM, Kirigin FF, Bokulich NA, Yamanishi S, Teitler I, Chung J, Sohn J, Barber CM, Goldfarb DS, Raju K, Abubucker S, Zhou Y, Ruiz VE, Li H, Mitreva M, Alekseyenko AV, Weinstock GM, Sodergren E, Blaser MJ. (2015) Metabolic and metagenomic outcomes from early-life pulsed antibiotic treatment. Nature Communication. 2015 Jun 30, 6:7486.

11.  Cox LM,  Yamanishi S,  Sohn J,  Alekseyenko AV,   Leung JM,  Cho I,  Kim S,  Li H,  Gao Z, Mahana D,  Zárate Rodriguez GZ.,  Rogers AB,  Robine N,  Loke P,  Blaser MJ. (2014)   Altering the intestinal microbiota during a critical developmental window has lasting metabolic consequences. Cell. 2014 Aug 14:158(4):705–721.

12.  Redel H, Gao Z, Li H, Alekseyenko AV, Zhou Y, Perez-Perez GI, Weinstock G, Sodergren E,  Blaser, MJ. (2013)   Quantitation and composition of cutaneous microbiota in diabetic and non-diabetic men. Journal of Infectious Disease.  2013 Apr, 207(7):1105-14.

13.  Cho I, Yamanishi S, Cox L, Meth B, Zavadil J, Li K, Gao Z, Mahana D, Raju K, Teitler I, Li H, Alekseyenko A, Blaser MJ. (2012)   Subtherapeutic antibiotics alter the murine colonic microbiome and early life adiposity. Nature.  2012 Aug 30, 488(7413): 621-626.

Microbiome in Cancer

1.   Meng Y, Wang C, Usyk M, Kwak S, Peng C, Hu KS, Oberstein PE, Krogsgaard M, Li H, Hayes RB, Ahn J. Association of tumor microbiome with survival in resected early-stage PDAC. mSystems. 2025 Mar 18;10(3):e0122924. doi: 10.1128/msystems.01229-24. Epub 2025 Feb 27. PMID: 40013793; PMCID: PMC11915875. 

2. Kwak S, Wang C, Usyk M, Wu F, Freedman ND, Huang WY, McCullough ML, Um CY, Shrubsole MJ, Cai Q, Li H, Ahn J, Hayes RB. Oral Microbiome and Subsequent Risk of Head and Neck Squamous Cell Cancer. JAMA Oncol. 2024 Nov 1;10(11):1537-1547. doi: 10.1001/jamaoncol.2024.4006. PMID: 39325441; PMCID: PMC11428028. 

3. Natalini JG, Wong KK, Nelson NC, Wu BG, Rudym D, Lesko MB, Qayum S, Lewis TC, Wong A, Chang SH, Chan JCY, Geraci TC, Li Y, Wang C, Li H, Pamar P, Schnier J, Mahoney IJ, Malik T, Darawshy F, Sulaiman I, Kugler MC, Singh R, Collazo DE, Chang M, Patel S, Kyeremateng Y, McCormick C, Barnett CR, Tsay JJ, Brosnahan SB, Singh S, Pass HI, Angel LF, Segal LN. Longitudinal Lower Airway Microbial Signatures of Acute Cellular Rejection in Lung Transplantation. Am J Respir Crit Care Med. 2024 Jun 15;209(12):1463-1476. doi: 10.1164/rccm.202309-1551OC. PMID: 38358857; PMCID: PMC11208954. 

4. Wu F, Yang L, Hao Y, Zhou B, Hu J, Yang Y, Bedi S, Sanichar NG, Cheng C, Perez-Perez G, Tseng W, Tseng W, Tseng M, Francois F, Khan AR, Li Y, Blaser MJ, Shu XO, Long J, Li H, Pei Z, Chen Y. Oral and gastric microbiome in relation to gastric intestinal metaplasia. Int J Cancer. 2022 Mar 15;150(6):928-940. doi: 10.1002/ijc.33848. Epub 2021 Nov 5. PMID: 34664721; PMCID: PMC8770574.

5. Prakash A, Peters BA, Cobbs E, Beggs D, Choi H, Li H, Hayes RB, Ahn J. Tobacco smoking and the fecal microbiome in a large, multi-ethnic cohort. Cancer Epidemiology and Prevention Biomarkers. 2021 Jan 1.

6.  Nolan-Kenney R, Wu F, Hu J, Yang L, Kelly D, Li H, Jasmine F, Kibriya MG, Parvez F, Shaheen I, Sarwar G, Ahmed A, Eunus M, Islam T, Pei Z, Ahsan H, Chen Y. The Association Between Smoking and Gut Microbiome in Bangladesh. Nicotine Tob Res. 2020 Jul 16;22(8):1339-1346. 

7. TTsay JJ, Darawshy F, Wang C, Kwok B, Wong KK, Wu BG, Sulaiman I, Zhou H, Isaacs B, Kugler MC, Sanchez E, Bain A, Li Y, Schluger R, Lukovnikova A, Collazo D, Kyeremateng Y, Pillai R, Chang M, Li Q, Vanguri RS, Becker AS, Moore WH, Thurston G, Gordon T, Moreira AL, Goparaju CM, Sterman DH, Tsirigos A, Li H, Segal LN, Pass HI. Lung Microbial and Host Genomic Signatures as Predictors of Prognosis in Early-Stage Adenocarcinoma. Cancer Epidemiol Biomarkers Prev. 2024 Nov 1;33(11):1433-1444. doi: 10.1158/1055-9965.EPI-24-0661. PMID: 39225784; PMCID: PMC11530314.

8.  Diefenbach CS, Peters BA, Li H, Raphael B, Moskovits T, Hymes K, Schluter J, Chen J, Bennani NN, Witzig TE, Ahn J. Microbial dysbiosis is associated with aggressive histology and adverse clinical outcome in B-cell non-Hodgkin lymphoma. Blood Adv. 2021 Mar 9;5(5):1194-1198. 

9.  Tsay JJ, Wu BG, Sulaiman I, Gershner K, Schluger R, Li Y, Yie TA, Meyn P, Olsen E, Perez L, Franca B, Carpenito J, Iizumi T, El-Ashmawy M, Badri M, Morton JT, Shen N, He L, Michaud G, Rafeq S, Bessich JL, Smith RL, Sauthoff H, Felner K, Pillai R, Zavitsanou AM, Koralov SB, Mezzano V, Loomis CA, Moreira AL, Moore W, Tsirigos A, Heguy A, Rom WN, Sterman DH, Pass HI, Clemente JC, Li H, Bonneau R, Wong KK, Papagiannakopoulos T, Segal LN. Lower Airway Dysbiosis Affects Lung Cancer Progression. Cancer Discov. 2021 Feb;11(2):293-307. 

10.  Ganly I, Yang L, Giese RA, Hao Y, Nossa CW, Morris LGT, Rosenthal M, Migliacci J, Kelly D, Tseng W, Hu J, Li H, Brown S, Pei Z. Periodontal pathogens are a risk factor of oral cavity squamous cell carcinoma, independent of tobacco and alcohol and human papillomavirus. Int J Cancer. 2019 Jan 22. 

11.   Wu J, Peters BA, Dominianni C, Zhang Y, Pei Z, Yang L, Ma Y,  Purdue MP, Jacobs EJ, Gapstur SM, Li H, Alekseyenko AV, Hayes RB, and Ahn J. (2016)  Cigarette smoking and the oral microbiome in a large study of American adults. ISME journal. 2016 Mar 25.

Microbiome in Others

1. Kwak S, Usyk M, Beggs D, Choi H, Ahdoot D, Wu F, Maceda L, Li H, Im EO, Han HR, Lee E, Wu AH, Hayes RB, Ahn J. Sociobiome - Individual and neighborhood socioeconomic status influence the gut microbiome in a multi-ethnic population in the US. NPJ Biofilms Microbiomes. 2024 Mar 11;10(1):19. doi: 10.1038/s41522-024-00491-y. PMID: 38467678; PMCID: PMC10928180. 

2. Zaidan N, Wang C, Chen Z, Lieske JC, Milliner D, Seide B, Ho M, Li H, Ruggles KV, Modersitzki F, Goldfarb DS, Blaser M, Nazzal L. Multiomics Assessment of the Gut Microbiome in Rare Hyperoxaluric Conditions. Kidney Int Rep. 2024 Mar 11;9(6):1836-1848. doi: 10.1016/j.ekir.2024.03.004. PMID: 38899198; PMCID: PMC11184406. 

3. Wu F, Davey S, Clendenen TV, Koenig KL, Afanasyeva Y, Zhou B, Bedi S, Li H, Zeleniuch-Jacquotte A, Chen Y. Gut Microbiota and Subjective Memory Complaints in Older Women. J Alzheimers Dis. 2022 May 9. doi: 10.3233/JAD-220011. Epub ahead of print. PMID: 35570486.

4. Sulaiman I, Chung M, Angel L, Koralov S, Wu B, Yeung S, Krolikowski K, Li Y, Duerr R, Schluger R, Thannickal S, Koide A, Rafeq S, Barnett C, Postelnicu R, Wang C, Banakis S, Perez-Perez L, Jour G, Shen G, Meyn P, Carpenito J, Liu X, Ji K, Collazo D, Labarbiera A, Amoroso N, Brosnahan S, Mukherjee V, Kaufman D, Bakker J, Lubinsky A, Pradhan D, Sterman D, Heguy A, Uyeki T, Clemente J, de Wit E, Schmidt AM, Shopsin B, Desvignes L, Wang C, Li H, Zhang B, Forst C, Koide S, Stapleford K, Khanna K, Ghedin E, Weiden M, Segal L. Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome. 2021. Nature Microbiology PMC8010736. doi: 10.21203/rs.3.rs-266050/v1.

5.  Osborne G, Wu F, Yang L, Kelly D, Hu J, Li H, Jasmine F, Kibriya MG, Parvez F, Shaheen I, Sarwar G, Ahmed A, Eunus M, Islam T, Pei Z, Ahsan H, Chen Y. The association between gut microbiome and anthropometric measurements in Bangladesh. Gut Microbes.2019 May 29; 1-14. 

6.  Yang L, Hao Y, Hu J, Kelly D, Li H, Brown S, Tasker C, Roche NE, Chang TL, Pei Z. (2017) Differential effects of Depot medroxyprogesterone acetate administration on vaginal microbiome in White and Black women. Emerging Microbes & Infections. 8(1):197-210 January 2019  

7.   Wu F, Yang L, Islam MT, Jasmine F, Kibriya MG, Nahar J, Barmon B, Parvez F, Sarwar G, Ahmed A, Eunus M, Islam T, Slavkovich V, Hu J, Li H, Graziano JH, Pei Z, Ahsan H, Chen Y. The role of gut microbiome and its interaction with arsenic exposure in carotid intima-media thickness in a Bangladesh population. Environment international. 2018 123:104-113

8.   Gonzalez ME, Schaffer JV, Orlow SJ, Gao Z, Li H, Alekseyenko AV, Blaser MJ. (2016) Cutaneous microbiome effects of fluticasone propionate cream and adjunctive bleach baths in childhood atopic dermatitis. J Am Acad Dermatol. 2016 Sep, 75(3):481-493.e8.

9.   Kienesberger S, Perez-Perez GI, Rivera-Correa JL, Tosado-Acevedo R, Li H, Dubois A, Gonzalez-Martinez JA, Gloria Dominguez Bello M, Blaser, MJ.  (2012)   Serologic host response to Helicobacter pylori and Campylobacter jejuni in socially housed Rhesus macaques (Macacamulatta). Gut Pathogens. 2012 Aug 24, 4(1):9.

Diabetes and Weight Loss

1.  Shi Y, Sevick MA, Tang H, Wang C, Zhao Y, Yoon S, Li H, Jiang Y, Bai Y, Ong IH, Yang X, Su L, Levy N, Tamura K, Hu L. Culturally Tailored Social Media Intervention Improves Health Outcomes in Chinese Americans with Type 2 Diabetes: Preliminary Evidence from a Pilot RCT. J Gen Intern Med. 2025 Feb 27. doi: 10.1007/s11606-025-09430-9. Epub ahead of print. PMID: 40016380. 

2. Berube LT, Popp CJ, Curran M, Hu L, Pompeii ML, Barua S, Bernstein E, Salcedo V, Li H, St-Jules DE, Segal E, Bergman M, Williams NJ, Sevick MA. Diabetes Telemedicine Mediterranean Diet (DiaTeleMed) Study: study protocol for a fully remote randomized clinical trial evaluating personalized dietary management in individuals with type 2 diabetes. Trials. 2024 Jul 25;25(1):506. doi: 10.1186/s13063-024-08337-w. PMID: 39049121; PMCID: PMC11271038. 

3. Hu L, Shi Y, Wylie-Rosett J, Sevick MA, Xu X, Lieu R, Wang C, Li H, Bao H, Jiang Y, Zhu Z, Yeh MC, Islam N. Feasibility of a family-oriented mHealth intervention for Chinese Americans with type 2 diabetes: A pilot randomized control trial. PLoS One. 2024 Mar 11;19(3):e0299799. doi: 10.1371/journal.pone.0299799. PMID: 38466714; PMCID: PMC10927140. 

4. Arivazhagan L, Delbare S, Wilson RA, Manigrasso MB, Zhou B, Ruiz HH, Mangar K, Higa R, Brown E, Li H, Garabedian MJ, Ramasamy R, Moore KJ, Fisher EA, Theise ND, Schmidt AM. Sex differences in murine MASH induced by a fructose-palmitate-cholesterol-enriched diet. JHEP Rep. 2024 Sep 21;7(2):101222. doi: 10.1016/j.jhepr.2024.101222. PMID: 39911943; PMCID: PMC11795143. 

5. Yepuri G, Ramirez LM, Theophall GG, Reverdatto SV, Quadri N, Hasan SN, Bu L, Thiagarajan D, Wilson R, Díez RL, Gugger PF, Mangar K, Narula N, Katz SD, Zhou B, Li H, Stotland AB, Gottlieb RA, Schmidt AM, Shekhtman A, Ramasamy R. DIAPH1-MFN2 interaction regulates mitochondria-SR/ER contact and modulates ischemic/hypoxic stress. Nat Commun. 2023 Oct 30;14(1):6900. doi: 10.1038/s41467-023-42521-x. PMID: 37903764; PMCID: PMC10616211. 

6. Vanegas SM, Curado S, Gujral A, Valverde G, Parraga S, Aleman JO, Reid M, Elbel B, Schmidt AM, Heffron SP, Segal E, Li H, Abrams C, Sevick MA, Popp C, Armijos E, Merriwether EN, Ivezaj V, Ren-Fielding C, Parikh M, Jay M. Cohort profile: study design and baseline characteristics of an observational longitudinal weight loss cohort and biorepository of patients undergoing sleeve gastrectomy in the USA. BMJ Open. 2024 Aug 24;14(8):e081201. doi: 10.1136/bmjopen-2023-081201. PMID: 39181563; PMCID: PMC11344502. 

7. Kharmats AY, Popp C, Hu L, Berube L, Curran M, Wang C, Pompeii ML, Li H, Bergman M, St-Jules DE, Segal E, Schoenthaler A, Williams N, Schmidt AM, Barua S, Sevick MA. A randomized clinical trial comparing low-fat with precision nutrition-based diets for weight loss: impact on glycemic variability and HbA1c. Am J Clin Nutr. 2023 Aug;118(2):443-451. doi: 10.1016/j.ajcnut.2023.05.026. Epub 2023 May 24. PMID: 37236549; PMCID: PMC10447469. 

8. Wilson RA, Arivazhagan L, Ruiz HH, Zhou B, Qian K, Manigrasso MB, Bernadin R, Mangar K, Shekhtman A, Li H, Ramasamy R, Schmidt AM. Pharmacological antagonism of receptor for advanced glycation end products signaling promotes thermogenesis, healthful body mass and composition, and metabolism in mice. Obesity (Silver Spring). 2023 Jul;31(7):1825-1843. doi: 10.1002/oby.23774. Epub 2023 May 25. PMID: 37231626; PMCID: PMC10790363. 

9. Senatus L, Egaña-Gorroño L, López-Díez R, Bergaya S, Aranda JF, Amengual J, Arivazhagan L, Manigrasso MB, Yepuri G, Nimma R, Mangar KN, Bernadin R, Zhou B, Gugger PF, Li H, Friedman RA, Theise ND, Shekhtman A, Fisher EA, Ramasamy R, Schmidt AM. DIAPH1 mediates progression of atherosclerosis and regulates hepatic lipid metabolism in mice. Commun Biol. 2023 Mar 17;6(1):280. doi: 10.1038/s42003-023-04643-2. PMID: 36932214; PMCID: PMC10023694. 

10. Bruno J, Verano M, Vanegas SM, Weinshel E, Ren-Fielding C, Lofton H, Fielding G, Schwack B, Chua DL, Wang C, Li H, Alemán JO. Body Weight and Prandial Variation of Plasma Metabolites in Subjects Undergoing Gastric Band-Induced Weight Loss. Obes Med. 2022 Aug;33:100434. doi: 10.1016/j.obmed.2022.100434. Epub 2022 Jul 1. PMID: 37216066; PMCID: PMC10195098. 

11. Hu L, Islam N, Zhang Y, Shi Y, Li H, Wang C, Sevick MA. Leveraging Social Media to Increase Access to an Evidence-Based Diabetes Intervention Among Low-Income Chinese Immigrants: Protocol for a Pilot Randomized Controlled Trial. JMIR Res Protoc. 2022 Oct 28;11(10):e42554. doi: 10.2196/42554. PMID: 36306161; PMCID: PMC9652737. 

12. St-Jules DE, Hu L, Woolf K, Wang C, Goldfarb DS, Katz SD, Popp C, Williams SK, Li H, Jagannathan R, Ogedegbe O, Kharmats AY, Sevick MA. An Evaluation of Alternative Technology-Supported Counseling Approaches to Promote Multiple Lifestyle Behavior Changes in Patients With Type 2 Diabetes and Chronic Kidney Disease. J Ren Nutr. 2023 Jan;33(1):35-44. doi: 10.1053/j.jrn.2022.05.006. Epub 2022 Jun 22. PMID: 35752400; PMCID: PMC9772360. 

13. Popp CJ, Hu L, Kharmats AY, Curran M, Berube L, Wang C, Pompeii ML, Illiano P, St-Jules DE, Mottern M, Li H, Williams N, Schoenthaler A, Segal E, Godneva A, Thomas D, Bergman M, Schmidt AM, Sevick MA. Effect of a Personalized Diet to Reduce Postprandial Glycemic Response vs a Low-fat Diet on Weight Loss in Adults With Abnormal Glucose Metabolism and Obesity: A Randomized Clinical Trial. JAMA Netw Open. 2022 Sep 1;5(9):e2233760. doi: 10.1001/jamanetworkopen.2022.33760. PMID: 36169954; PMCID: PMC9520362. 

14. Bruno J, Verano M, Vanegas SM, Weinshel E, Ren-Fielding C, Lofton H, Fielding G, Schwack B, Chua DL, Wang C, Li H, Alemán JO. Body Weight and Prandial Variation of Plasma Metabolites in Subjects Undergoing Gastric Band-Induced Weight Loss. Obes Med. 2022 Aug;33:100434. doi: 10.1016/j.obmed.2022.100434. Epub 2022 Jul 1. PMID: 37216066; PMCID: PMC10195098. 

15. Popp CJ, Zhou B, Manigrasso MB, Li H, Curran M, Hu L, St-Jules DE, Alemán JO, Vanegas SM, Jay M, Bergman M, Segal E, Sevick MA, Schmidt AM. Soluble Receptor for Advanced Glycation End Products (sRAGE) Isoforms Predict Changes in Resting Energy Expenditure in Adults with Obesity during Weight Loss. Curr Dev Nutr. 2022 Mar 29;6(5):nzac046. doi: 10.1093/cdn/nzac046. PMID: 35542387; PMCID: PMC9071542.

16. Manigrasso MB, Rabbani P, Egaña-Gorroño L, Quadri N, Frye L, Zhou B, Reverdatto S, Ramirez LS, Dansereau S, Pan J, Li H. Small-molecule antagonism of the interaction of the RAGE cytoplasmic domain with DIAPH1 reduces diabetic complications in mice. Science Translational Medicine. 2021 Nov 24;13(621):eabf7084.

17. Ruiz HH, Nguyen A, Wang C, He L, Li H, Hallowell P, McNamara C, Schmidt AM. AGE/RAGE/DIAPH1 axis is associated with immunometabolic markers and risk of insulin resistance in subcutaneous but not omental adipose tissue in human obesity. International Journal of Obesity. 2021 Jun 8:1-2.

18.  MacLean M, Juranek J, Cuddapah S, López-Díez R, Ruiz HH, Hu J, Frye L, Li H, Gugger PF, Schmidt AM. Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner. Journal of neuroinflammation. 2021 Dec;18(1):1-24.

19.  St-Jules DE, Woolf K, Goldfarb DS, Pompeii ML, Li H, Wang C, Mattoo A, Marcum ZA, Sevick MA. Feasibility and Acceptability of mHealth Interventions for Managing Hyperphosphatemia in Patients Undergoing Hemodialysis. J Ren Nutr. 2020 Nov 4:S1051-2276(20)30207-7. 

20.  Senatus L, López-Díez R, Egaña-Gorroño L, Liu J, Hu J, Daffu G, Li Q, Rahman K, Vengrenyuk Y, Barrett TJ, Dewan MZ, Guo L, Fuller D, Finn AV, Virmani R, Li H, Friedman RA, Fisher EA, Ramasamy R, Schmidt AM. RAGE impairs murine diabetic atherosclerosis regression and implicates IRF7 in macrophage inflammation and cholesterol metabolism. JCI Insight. 2020 Jul 9;5(13):e137289. 

21.   Abdulle A, Inman CK, Saleh A, Noshi M, Galani D, Abdelwareth L, Alsafar H, Elfatih A, Shamsi HA,  Ali R, Li H, Ramasamy R, Schmidt AM, Benbarka MM, and Hassan MH. Metabolic Dysfunction in Emirati Subjects in Abu Dhabi: Relationship to Levels of Soluble RAGEs. Journal of Clinical & Translational Endocrinology. 2019 (16):100192- (# 3864802)

22.  Popp, CJ, St-Jules, DE, Hu, L, Ganguzza, L, Illiano, P, Curran, Mt, Li, H, Schoenthaler, A, Bergman, M, Schmidt, AM, Segal, E, Godneva, A, Sevick, MA. (2019).  The Rationale And Design Of The Personal Diet Study, A Randomized Clinical Trial Evaluating A Personalized Approach To Weight Loss In Individuals With Pre-Diabetes And Early-Stage Type 2 Diabetes. Contemporary Clinical Trials. 2019 Mar 04, 79:80-88

23.  Abedini A, Cao P, Plesner A, Zhang J, He M, Derk J, Patil SA, Rosario R, Lonier J, Song F, Koh H, Li H, Raleigh DP, Schmidt AM. RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity. J Clin Invest. 2018 Feb 1,128(2):682-698. doi: 10.1172/JCI85210.

24.  Litwinoff EMS, Gold MY, Singh K, Hu J, Li H, Cadwell K, Schmidt AM. (2018) Myeloid ATG16L1 does not affect adipose tissue inflammation or body mass in mice fed high fat diet. Obes Res Clin Pract. 2017 Nov 2. 

25.  Sevick MA, Woolf K, Mattoo A, Katz S, Li H, St-Jules DE, Jagannathan R, Hu L, Pompeii ML, Ganguzza L, Li Z, Sierra A, Williams SK, Goldfarb DS. (2018)  The Healthy Hearts and Kidneys (HHK) Study: Design of a 2x2 RCT of Technology-Supported Self-Monitoring and Social Cognitive Theory-based Counseling to Engage Overweight People with Diabetes and Chronic Kidney Disease in Multiple Lifestyle Changes.  Contemporary Clinical Trials. 2018 Jan, 64:265-273. 

26.   Inman CK,  Junaibi A, Koh H, Abdulle A,  Ali R, Naeemi AA,  Zaabi EA,  Oumeziane N, Bastaki MA, Houqani MA,   Maskari FA, Dhaheri AA, Shah S,  Wareth LA, Mahmeed WA, Alsafar H,   Anouti FA, Hosani AA, Haji M, Galani D,  O’Connor MJ, Ahn J, Kirchhoff T,  Sherman S, Hayes RB, Li H, Ramasamy R, Schmidt AM.  The AGE-RAGE Axis in an Arab Population: The United Arab Emirates Healthy Futures (UAEHFS) Pilot Study. Diabetes Research and Clinical Practice. 2017 Aug 14, 10:1-8. 

27.   López-Díez R, Shen X, Daffu G, Khursheed M, Hu J, Song F, Rosario R, Xu Y, Li Q, Xi X, Zou Y, Li H, Schmidt A, and Yan S. (2017) Ager Deletion Enhances Ischemic Muscle Inflammation, Angiogenesis, and Blood Flow Recovery in Diabetic Mice. Arterioscler Thromb Vasc Biol. 2017 Aug, 37(8):1536-1547.

28.   Juranek JK, Daffu GK, Geddis MS, Li H, Rosario R, Kaplan BJ, Kelly L, Schmidt AM. (2016) Soluble RAGE Treatment Delays Progression of Amyotrophic Lateral Sclerosis in SOD1 Mice. Front Cell Neurosci. 2016 May 9, 10:117.

29.   Jagannathan R, Sevick MA, Li H, Gertner R, Chetrit A,  Roth J,  Bergman M. (2016)  Elevated 1-Hour Plasma Glucose Levels are Associated With Dysglycemia, Impaired Beta-Cell Function and Insulin Sensitivity: Pilot Study From A Real World Health Care Setting. Endocrine Journal. 2016 Apr, 52(1):172-5.

30.    Song F, Hurtado del Pozo C, Rosario R, Zou Y, Ananthakrishnan R, Xu X, Patel P, Benoit V, Yan S, Li H, Friedman R, Kim J, Ramasamy R, Ferrante Jr. A, Schmidt AM. (2014)    RAGE Regulates the Metabolic and Inflammatory Response to High Fat Feeding in Mice. Diabetes.2014 Jun, 63(6):1948-65.

Cancer

1. Stevens ER, Thomas J, Martinez-Lopez N, Fagerlin A, Ciprut S, Shedlin M, Gold HT, Li H, Davis JK, Campagna A, Bhat S, Warren R, Ubel P, Ravenell JE, Makarov DV. Limited Evidence of Shared Decision Making for Prostate Cancer Screening in Audio-Recorded Primary Care Visits Among Black Men and their Healthcare Providers. J Immigr Minor Health. 2024 Oct;26(5):866-877. doi: 10.1007/s10903-024-01606-5. Epub 2024 Jun 1. PMID: 38822923; PMCID: PMC11412785. 

2.   Rude T, Walter D, Ciprut S, Kelly MD, Wang C, Fagerlin A, Langford AT, Lepor H, Becker DJ, Li H, Loeb S, Ravenell J, Leppert JT, Makarov DV. Interaction between race and prostate cancer treatment benefit in the Veterans Health Administration. Cancer. 2021. Vol 127 issue 21, 3985-3990.

3.    Makarov DV, Feuer Z, Ciprut S, Lopez NM, Fagerlin A, Shedlin M, Gold HT, Li H, Lynch G, Warren R, Ubel P, Ravenell JE. Randomized trial of community health worker-led decision coaching to promote shared decision-making for prostate cancer screening among Black male patients and their providers. Trials. 2021 Feb 10;22(1):128. 

4.   Becker DJ, Rude T, Walter D, Wang C, Loeb S, Li H, Ciprut S, Kelly M, Zeliadt SB, Fagerlin A, Lepor H, Sherman S, Ravenell JE, Makarov DV. The Association of Veterans' PSA Screening Rates with Changes in USPSTF Recommendations. J Natl Cancer Inst. 2020 Aug 14:djaa120. 

5.   Rude T, Walter D, Loeb S, Li H, Cipruit S, Zeliadt S, Fagerlin A, Lepor H, Sherman S  , Ravenell J, Makarov D. (2018) PD52-11 PSA screening of black veterans before, during, and after implementation of the 2012 us preventative services task force recommendations. The Journal of Urology 199 (4), e985-e986 

6.  Borofsky MS, Walter D, Li H, Shah O, Goldfarb DS, Sosa RE, Makarov DV. (2015) National Disparities in Recommended Care for Patients with Obstructive Pyelonephritis. Journal of Urology. 2015, 193(3):851-6.

7.   Youn P, Li H, Milano MT, Stovall M, Constine L,Travis LB. (2013) Long term survival among Hodgkin’s lymphoma patients with gastrointestinal cancer: a population-based study. Annals of Oncology. 2013 Jan, 24(1):202-8.

8.   Moore LE, Jaeger E, Nickerson ML, Brennan P, De Vries S, Roy R, Toro J, Li H, Karami S, Lenz P, Zaridze D, Janout V, Bencko V, Navratilova M, Szeszenia-Dabrowska N, Mates D, Linehan WM, Merino M, Simko J, Pfeiffer R, Boffetta P, Hewitt S, Rothman N, Chow WH, Waldman FM. (2012)   Genomic copy number alterations in clear cell renal carcinoma: associations with case characteristics and mechanisms of VHL gene inactivation. Nature Oncogenesis. 2012 Jun 25,  

9.    Milano MT, Li H, Constine L, Travis LB. (2012)   Variables Affecting Survival After Second Primary Lung Cancer: A Population-based Study of 187 Hodgkin’s Lymphoma Patients. Journal of Thoracic Disease. 2012 Feb 4, 4(1):22-29.

10.   Milano MT, Li H, Constine L, Travis LB. (2011), Survival After Second Primary Lung Cancer: A Population-based Study of 187 Hodgkin Lymphoma Patients. Cancer. 2011 Dec 15,117(24):5538-5547.

11.   Matsuno RK, Constantino JP, Ziegler RG, Anderson GL, Li H, Pee D, Gail MH. (2011) Projecting Individualized Absolute Invasive Breast Cancer Risk in Asian and Pacific Island American Women. Journal of National Cancer Institute. 2011 Jun 22,103(12):951-61.

12.   Milano MT, Li H, Gail MH, Constine L, Travis LB. (2010) Long-term Survival Among Hodgkin Lymphoma Patients With Breast Cancer: A Population-based Study. Journal of Clinical Oncology. 2010 Dec 1, 28(34):5088-5096.

Health Care

1.   Hu L, Lin NF, Shi Y, Cao J, Sevick MA, Li H, Beasley JM, Levy N, Tamura K, Xu X, Jiang Y, Ong I, Yang X, Bai Y, Su L, Chan SW, Yi SS. The Integrating Cultural Aspects Into Diabetes Education (INCLUDE) Study to Prevent Diabetes in Chinese Immigrants: Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2024 Nov 19;13:e65455. doi: 10.2196/65455. PMID: 39560984; PMCID: PMC11615548.

2.  Makarov DV, Li H, Lepor H, Blustein J, Gross CP, and Blustein J. (2016) “Teaching Hospitals and the Disconnect between Technology Adoption and Comparative Effectiveness Research: The Case of the Surgical Robot”. Medical Care Research and Review. 2016 Mar 30.

3.  Jubelt JE, Graham J, Maeng DD, Li H, Epstein AJ, Metlay JP. (2014)   Patient ratings of case managers in a medical home: associations with patient satisfaction and healthcare utilization. Annals of Internal Medicine. 2014 Nov 18,161(10 Suppl):S59-65.

4.   Makarov  D, Li H, Yu J, Makary M, Braithwaite S, Sherman S, Taneja S, Penson D, Lepor H, Desai, R, Blustein, J, Gross C (2012)   Factors Associated with the Early Acquisition of the Surgical Robot by Hospitals in the United States. Journal of urology.  2012:187(4):E172-E172.

Other Diseases

1.  Gago J, Filardo TD, Conderino S, Magaziner SJ, Dubrovskaya Y, Inglima K, Iturrate E, Pironti A, Schluter J, Cadwell K, Hochman S, Li H, Torres VJ, Thorpe LE, Shopsin B. Pathogen Species Is Associated With Mortality in Nosocomial Bloodstream Infection in Patients With COVID-19. Open Forum Infect Dis. 2022 Apr 5;9(6):ofac083. doi: 10.1093/ofid/ofac083. PMID: 35607701; PMCID: PMC8992347. 

2. Gomes C, Zuniga M, Crotty KA, Qian K, Tovar NC, Lin LH, Argyropoulos KV, Clancy R, Izmirly P, Buyon J, Lee DC, Yasnot-Acosta MF, Li H, Cotzia P, Rodriguez A. Autoimmune anti-DNA and anti-phosphatidylserine antibodies predict development of severe COVID-19. Life science alliance. 2021 Nov 1;4(11).

3.  Derk J, Bermudez Hernandez K, Rodriguez M, He M, Koh H, Abedini A, Li H, Fenyö D, Schmidt AM. Diaphanous 1 (DIAPH1) is Highly Expressed in the Aged Human Medial Temporal Cortex and Upregulated in Myeloid Cells During Alzheimer's Disease. Journal of Alzheimer's and Dementia 2018, 64(3):995-1007.

4.   Ruiz V, Gottwick C, Livanos A, Li H, Blaser MJ. (2014)   Understanding the effect of early-life pulsed antibiotic treatment on mucosal T-lymphocyte populations. Journal of Immunology. 2014 May 1,192(1 Suppl):S133.3.

5.  Afonso MS, Sharma M, Schlegel MP, van Solingen C, Koelwyn GJ, Shanley LC, Beckett L, Peled D, Rahman K, Giannarelli C, Li H, Brown EJ, Khodadadi-Jamayran A, Fisher EA, Moore KJ. miR-33 Silencing Reprograms the Immune Cell Landscape in Atherosclerotic Plaques. Circ Res. 2021 Feb 17. PMID: 33593073.