Publications

7. Hiroto S. Fukushima*, & Hiroyuki Takeda*. “Coordinated action of multiple active histone modifications shapes the zygotic genome activation in teleost embryos” Nature communications (2025) https://doi.org/10.1038/s41467-025-60246-x *Co-coresponding

プレスリリース https://www.riken.jp/press/2025/20250616_2/index.html

ハイライト https://www.riken.jp/en/news_pubs/research_news/rr/20251120_1/index.html

6. Hiroto S. Fukushima*, Takafumi Ikeda, Shinra Ikeda & Hiroyuki Takeda*. “Cell cycle length governs heterochromatin reprogramming during early development in non-mammalian vertebrates” EMBO Reports (2024) https://doi.org/10.1038/s44319-024-00188-5 *Co-coresponding (Selected as the cover picture)

5. Hiroto S. Fukushima, Hiroyuki Takeda & Ryohei Nakamura. “Incomplete erasure of histone marks during epigenetic reprogramming in medaka early development” Genome Research 33(4): 572-586 (2023) https://www.genome.org/cgi/doi/10.1101/gr.277577.122. (Selected as the cover picture)

4. Hiroto S. Fukushima, Hiroyuki Takeda & Ryohei Nakamura. “Targeted Manipulation of Histone Modification in Medaka Embryos” Methods in Molecular Biology. (2022) https://doi.org/10.1007/978-1-0716-2724-2_20

3. Hiroto S. Fukushima, Hiroyuki Takeda & Ryohei Nakamura. “Site-specific Epigenetic Editing of Histone Code In Vivo”Translational Epigenetics, in press, (a chapter in the book “Site Specific and Global Epigenomic Editing”)

2. Hiroto S. Fukushima, Hiroyuki Takeda & Ryohei Nakamura. “Targeted in vivo epigenome editing of H3K27me3” Epigenetics & Chromatin 12: 17 (2019) https://doi.org/10.1186/s13072-019-0263-z

1. Napo K. M. Cheung, Ryohei Nakamura, Ayako Uno, Masahiko Kumagai, Hiroto S. Fukushima, Shinichi Morishita, Hiroyuki Takeda. “Unlinking the methylome pattern from nucleotide sequence, revealed by large-scale in vivo genome engineering and methylome editing in medaka fish” PLoS Genet. 13(12): e1007123. (2017) https://doi.org/10.1371/journal.pgen.1007123

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