URL
Google Scholar : https://scholar.google.com/citations?user=-eVwTpcAAAAJ
ORCID : 0000-0002-8186-1085 - https://orcid.org/0000-0002-8186-1085
Researcher ID ( publications and as-hoc peer-review ) : J-2827-2012 - https://www.webofscience.com/wos/author/record/J-2827-2012
Editorial contribution : https://loop.frontiersin.org/people/1884577/editorial
* Please, find Scientific Impact & Outreach are in blue.
BCL11b interacts with RNA and proteins involved in RNA processing and developmental diseases (download the PDF file)
H. Sobhy*, M. De Rovere*, A. Ait-Ammar*, ... et al... , C. Schwartz, O. Rohr
Biochim Biophys Acta Gene Regul Mech. 2024; doi: 10.1016/j.bbagrm.2024.195065; PMID: 39455000
Our data support subsequent grants and publications, including PhD student publications [ e.g., DOI ], proving data utility and reproducibility.
Highly interacting regions of the human genome are enriched with enhancers and bound by DNA repair proteins (download the PDF file)
H. Sobhy*, R. Kumar, J. Lewerentz, L. Lizana* and P. Stenberg*
Scientific Reports, 2019; doi: 10.1038/s41598-019-40770-9; PMID: 30872630
Our computational analyses subsequently validated by independent experimental studies, examples: Prof. Aziz Sancar's team at UNC - PMID: 33771559; in addition to other articles including PMID: 33057195, PMID: 34598804, PMID: 27851967, and PMID: 28735753
Genome contact map explorer: a platform for the comparison, interactive visualization and analysis of genome contact maps (download the PDF file)
R. Kumar, H. Sobhy, L. Lizana and P. Stenberg
Nucleic Acids Research, 2017; doi: 10.1093/nar/gkx644; PMID: 28973466
Identification of giant Mimivirus protein functions using RNA interference (download the PDF file)
H. Sobhy, B. La Scola, I. Pagnier, D. Raoult, P. Colson
Frontiers in Microbiology, 2015; doi: 10.3389/fmicb.2015.00345; PMID: 25972846
Our functional genomics methods were independently validated by the Michael Rossmann team (Purdue University) in their concurrent study of viral protein structure (PMID: 25982526).
The optimized functional genomics, and protein expression and structure protocols were utilized for first time to study giant viral proteins. the methods were used in Nature (PMID: 26934229), and in JVI (PMID: 29514904) Journals.
Recombinant expression of Mimivirus L725 ORFan gene product (download the PDF file)
H. Sobhy, G. Gotthard, E. Chabrière, D. Raoult, P. Colson
Acta virologica; 2017; doi: 10.4149/av_2017_01_123; PMID: 28161966
Our functional genomics methods were independently validated by the Michael Rossmann team (Purdue University) in their concurrent study of viral protein structure (PMID: 25982526).
The optimized functional genomics, and protein expression and structure protocols were utilized for first time to study giant viral proteins. the methods were used in Nature (PMID: 26934229), and in JVI (PMID: 29514904) Journals.
The Potential Functions of Protein Domains during COVID Infection: An Analysis and a Review (download the PDF file | Preprint PDF : Apr/May 2020)
H. Sobhy*
MDPI COVID Journal 2021; doi: 10.3390/covid1010032
First report of the presence of a tubulin autoregulation motif in the C-terminal of the COVID nsp1 protein; later that same year, a Science study showed the involvement of the C-terminus in RNA translation. Our data can support future mechanistic studies and the identification of antiviral therapeutic targets."
Virophages and their interactions with giant viruses and host cells (download the PDF file)
H. Sobhy*
MDPI Proteomes (invited featured review), 2018; doi: 10.3390/proteomes6020023; PMID: 29786634
This is an Invited review / feature article
My work is cited on Wikipedia and featured in educational YouTube videos.
A comparative review of viral entry and attachment during large and giant dsDNA virus infections (download the PDF file)
H. Sobhy*
Archives of Virology, 2017; doi: 10.1007/s00705-017-3497-8; PMID: 28866775
I am grateful to our colleagues for their positive evaluation of our 2018 review as an ‘outstanding reading’ (PMID: 33647556): "A great review that compares entry and attachment during large and giant dsDNA virus infections, also showing the shape and structure of its viral particles."
A review of functional motifs utilized by viruses (download the PDF file)
H. Sobhy*
MDPI Proteomes, 2016; doi: 10.3390/proteomes4010003; PMID: 28248213
A bioinformatics pipeline to search functional motifs within whole-proteome data: a case study of poxviruses (download the PDF file)
H. Sobhy*
Virus Genes, 2016; doi: 10.1007/s11262-016-1416-9; PMID: 28000080
Shetti, a simple tool to parse, manipulate and search large datasets of sequences (download the PDF file)
H. Sobhy*
SGM Microbial Genomics, 2015; doi: 10.1099/mgen.0.000035; PMID: 28348820
Gemi: PCR primers prediction from multiple alignments (download the PDF file)
H. Sobhy*, P. Colson*
Comparative and Functional Genomics, 2012; doi: 10.1155/2012/783138; PMID: 23316117
Conceptualized the idea and developed the tool. The tool is still actively downloaded, reaching up to 25 / day and about 3000 times since 2012 (statistics shown in SourceForge Website, click HERE); attracted commercialization offers, and highlighted by standard methodological books and protocols, including MIMB (Vol. 1275) and a screenshot in Methods in Microbiology (Vol. 57, 2025).
Social influence and peer review — impact factor and citation (download the PDF file)
H. Sobhy*
EMBO reports, 2016; doi: 10.15252/embr.201642041; PMID: 26882557