Cellular Stress Physiology Lab
Dr. Harinder Singh
Dr. Harinder Singh
Welcome to the CSPL Research lab studying bacterial stress biology, antimicrobial resistance (AMR) mechanisms, and cold shock proteins. PhD and internship positions open.
We are always looking for highly motivated students and researchers who are passionate about understanding microbial biology, host-pathogen interactions, antimicrobial resistance, molecular mechanisms of stress adaptation, and biotechnology-driven solutions to biological problems.
We welcome applications from candidates with backgrounds in Microbiology, Molecular Biology, Biotechnology, Biochemistry, Biomedical Sciences, Life Sciences and related disciplines
Candidates with experience in microbiological techniques, molecular biology methods, bioinformatics, microbial genomics, protein engineering, or antimicrobial research are particularly encouraged to apply.
Students interested in gaining research experience may apply for: Short-term research projects, Summer internships, Final-year dissertation projects, Laboratory training programs
We offer opportunities for: Dissertation projects, Research internships, Collaborative research projects, Training in advanced microbiology and molecular biology techniques
Prospective doctoral candidates interested in our research areas are encouraged to contact us regarding available positions and funding opportunities. Applicants should possess a strong academic background and a demonstrated interest in research.
Openings may periodically become available under funded research projects. Relevant announcements will be posted on this website.
Successful candidates typically demonstrate strong academic foundation in biological sciences, curiosity and scientific thinking, commitment to research and learning, ability to work independently and as part of a team, good written and oral communication skills
Prior research experience is advantageous but not mandatory.
Interested candidates can mail me at Harinder [dot] Singh [at] nmims [dot] edu.
Applications are reviewed throughout the year, and suitable candidates may be contacted when positions become available.
At the HS-Cellular Stress Physiology Lab, our research focuses on unraveling the intricate mechanisms behind microbial stress responses [focusing more on antimicrobial resistance (AMR)]. We study how microorganisms adapt to diverse environmental and antibiotic stress conditions, with a special emphasis on regulators, cold shock proteins, virulence, and pathogenicity. Our work bridges fundamental microbial physiology with applied biotechnology, aiming to discover novel enzymes and engineer microbial systems for improved resilience and industrial applications. Through our innovative research, we strive to contribute to advancements in industrial, medical, agricultural, and environmental biotechnology by exploring stress adaptation pathways that can lead to new therapeutic strategies and biotechnological innovations.
We employ a multidisciplinary approach that integrates:
- Microbiology: For growth and stress studies
- Molecular Biology: Cloning, gene knockout, and overexpression to study stress-response genes.
- Biochemistry: Enzyme activity assays and protein purification to elucidate the roles of stress-response proteins.
- Transcriptomics and Genomics: To identify global changes in gene expression under stress conditions.
- Proteomics: For identifying and quantifying stress-induced proteins.
Our research sits at the intersection of several branches of biology, including:
- Microbial Stress Biology: Understanding adaptive responses under harsh environmental conditions.
- Antimicrobial Resistance (AMR) Mechanisms : Exploring how stress proteins mediate resistance.
- Enzyme Biotechnology: Engineering bacterial enzymes for enhanced stability and industrial use.
To support our research goals, the HS-CSP Lab is equipped with state-of-the-art facilities, including:
- Molecular and microbial biology workstations for cloning, gene editing, and bacterial culture.
- Real-time PCR systems for gene expression studies.
- Protein purification systems and spectrophotometers for enzyme characterization.
- Bioinformatics tools for data analysis and visualization.
Our lab is committed to advancing the field of bacterial stress biology, with the ultimate goal of contributing to the development of new strategies to combat bacterial infections and improve industrial processes.
This lab is a part of Sunandan Divatia School of Science, NMIMS University — see full details at https://science.nmims.edu
For enquiries regarding available positions, projects, or collaborations, please contact me.
Dr. Harinder Singh, MNASc
Associate Professor
Department of Biological Sciences
Email: Harinder [dot] Singh [at] nmims [dot] edu
Google Scholar ID: vu5tFz4AAAAJ
Orcid ID: orcid.org/0000-0001-9373-8386
Scopus ID: 57087669600
Sciprofile: 1302106
ResearcherID: I-2264-2014
Vidwan-ID : 325482