Research

• Oxidative Coupling to Construct Biaryl Compounds

We develop catalytic and catalyst-free oxidative coupling reaction of aminonaphthalenes, phenols, and related aromatic compounds. Our goal is to control regio- and stereoselectivity in the formation of structurally diverse biaryls.

• Functional Biaryls and Polycyclic Molecules

Oxidative coupling provides rapid access to functional biaryls and polycyclic architectures. We investigate BINAM derivatives as ligand platforms and dibenzo[c,g]carbazoles as highly fluorescent molecular scaffolds. 

• Catalyst Design and Mechanism Study

We design catalytic systems based on noncovalent interactions and substrate–catalyst recognition. Mechanistic studies guide the development of selective catalysts and new ligand architectures.  

• Accelerated Reaction Development

We use microscale parallel experimentation to explore multidimensional reaction space, including catalysts, ligands, oxidants, additives, solvents, and temperature. HTE enables rapid identification of productive interactions and accelerates reaction optimization and discovery.