Research Interests

Research Overview

• Key tools: Nanopattern, Hydrogel
• Study 1. Control of cell behaviors such as migration, differentiation, and proliferation using geometrical cues
• Study 2. Tissue repair using a multiscale patterned patch
• Study 3. Investigation of cell-nanosstructure interaction using deformable nanostructures
• Study 4. Fabrication of in vitro 3D tissue models using structured hydrogels

1. Nanotopography-guided Tissue Engineering and Regenerative Medicine

• Application of nanopatterned patch for facilitated and scarless wound healing
• Investigation of tumor invasion using a micro-track-mimicking microtopography
• Investigation of nanostructure-cell interaction using nanocilia
• Synergistic enhancement of stem cell differentiation using nanotopographical and other physiologically-relevant cues

2. Brain on a chip (in vitro brain model)

• Fabrication of in vitro blood-brain barrier (BBB) model (BBB on a chip)
• Development of physiologically relevant 3D in vitro brain tissue models based on the co-culture of multiple types of brain tissue cells (Brain on a chip)