PUBLICATIONS
One-Shot Dual-Detection-Based Single-Molecule Super-Resolution Imaging Method for Real-Time Observation of Spatiotemporal Catalytic Activity Variations on the Plasmonic Gold NanoParticle Surface" Yingying Cao; Dongkyun Lee; Seungah Lee; Jin-Ming Lin; Seong Ho Kang, Anal. Chem. 96(5), 1957-1964 (2024): This article was selected as the Cover Article.
"Wavelength-Dependent Three-Dimensional Single-Molecule Superlocalization Imaging for Yoctomole Detection of Thyroid-Stimulating Hormone on a Quantum Dot Nanobiosensor" Junghwa Lee*; Seungah Lee*; Seong Ho Kang, Chinese Chemical Letters 34, 108383 (2023).
"Wavelength-Dependent Metal-Enhanced Fluorescence Biosensors via Resonance Energy Transfer Modulation" Seungah Lee*; Seong Ho Kang, Biosensors (Review) 13, 376 (2023).
"Supersensitive Detection of Single-Histamine Molecule on Nanoplates by Turn-On Small Molecule Fluorescence Sandwich Immunoassay" Seungah Lee*; Junghwa Lee*; Seong Ho Kang, Analyst 148, 714-718 (2023): This article was selected as the Hot Article.
"Real-Time Six-Dimensional Spatiotemporal Tracking of Single Anisotropic Nanoparticles in Live Cells by Integrated Multifunctional Light-Sheet Nanoscopy" Yingying Cao*; Seungah Lee; Kyungsoo Kim; Jong-Yong Kwak; Seong Ho Kang, Microchim. Acta 190, 54 (2023).
"Simultaneous Quantification of Thyroid Hormones using an Ultrasensitive Single-Molecule Fourplex Nanoimmunosensor in an Evanescent Field" Junghwa Lee; Seungah Lee; Gwang Lee; Seong Ho Kang, Biosens. Bioelectron. 220, 114894 (2023).
"Minimizing the Optical Illusion of Nanoparticles in Single Cells using Four-Dimensional Cuboid Multiangle Illumination-Based Light-Sheet Super-Resolution Imaging" Yingying Cao*; Seungah Lee*; Kyungsoo Kim; Seong Ho Kang, Anal. Chem. 94, 17877-17884 (2022).
"Nanomaterial-Based Single-Molecule Optical Immunosensors for Supersensitive Detection" S. Lee*; J. Lee; Y. Cao; C. An; S.H. Kang, Biosensors and Bioelectronics: X 11, 100191 (2022).
"Ultra-Sensitive Hypoxia Sensing at the Single-Molecule Level via Super-Resolution Quantum Dot-Linked Immunosandwich Assay" S. Lee*; J. Lee; B. Indra; H. Yu; S.H. Kang, ACS Sensors 7, 1372-1380 (2022).
"Excitation-Dependent Emissive FeSe Quantum Dots Induced by Chiral Interlayer Expansion and Their Multi-Color Bio-Imaging" J.Kwon; S.W. Jun; J. Kim; M. Lee; Y. Choi; D. Kim; M. Kim; S.G. Lee; S. Lee; S.H. Kang; K. Kyhm; C.-S. Kim; J.Y. Park; N.A. Kotov, C.-H. Park; J.Lee, Nano Today 45, 101535 (2022).
"Quantifying Intracellular Trafficking of Silica-Coated Magnetic Nanoparticles in Live Single Cells by Site-specific Direct Stochastic Optical Reconstruction Microscopy" Suresh Kumar Chakkarapani*; Tae Hwan Shin*; Seungah Lee*; Kyung-Soo Park; Gwang Lee; Seong Ho Kang, J. Nanobiotechnol. 19:398 (2021).
"Ultrasensitive Capsaicin Sensor based on Endogenous Single-Molecule Fluorophore Enhancement and Quenching Interface on Gold Nanoislands" Suresh Kumar Chakkarapani; Seungah Lee; Seong Ho Kang Bull. Korean Chem. Soc. 42, 1319-1326 (2021).
"Ultrasensitive Biogenic Amine Sensor using an Enhanced Multiple Nanoarray Chip based on Competitive Reactions in an Evanescent Field” Huong Thi Thuy Nguyen*; Seungah Lee*; Junghwa Lee; Ji-Hyoung Ha; Seong Ho Kang, Sens. Actuator B-Chem. 45, 130354 (2021).
"Cubic Spline-Based Depth-Dependent Localization of Mitochondria–Endoplasmic Reticulum Contacts by Three-Dimensional Light-Sheet Super-Resolution Microscopy" Yucheng Sun*; Seungah Lee*; Seong Ho Kang, Analyst 146, 4781-4788 (2021).
"Decrease in Membrane Fluidity and Traction Force Induced by Silica-Coated Magnetic Nanoparticles" Tae Hwan Shin; Abdurazak Aman Ketebo; Da Yeon Lee; Seungah Lee; Seong Ho Kang; Shaherin Basith; Balachandran Manavalan; Sungsu Park; Gwang Lee, J. Nanobiotechnol. 19:21 (2021).
"Toward Sub-Diffraction Imaging of Single-DNA Molecule Sensors Based on Stochastic Switching Localization Microscopy" Seungah Lee*; Indra Batjikh; Seong Ho Kang, Sensors 20(22), 6667; doi.org/10.3390/s20226667 (2020).
"Silica-Coated Magnetic Nanoparticles Decrease Migratory Activity of Human Bone Marrow-Derived Mesenchymal Stem Cells via Reduced Membrane Fluidity and Impaired Focal Adhesion" Tae Hwan Shin; Da Yeon Lee; Abdurazak Aman Ketebo; Seungah Lee*; Balachandran Manavalan; Shaherin Basith; Chanyoung Ahn; Seung Ho Kang; Sungsu Park; Gwang Lee, Nanomaterials 9, 1475; doi:10.3390/nano9101475 (2019).
"Supersensitive Detection of the Norovirus Immunoplasmon by 3D Total Internal Reflection Scattering Defocus Microscopy with Wavelength-Dependent Transmission Grating" Seungah Lee*; Sujin Ahn; Suresh Kumar Chakkarapani; Seong Ho Kang, ACS Sens. 4, 2515−2523 (2019).
"Photoluminescent and Self-assembled Hyaluronic Acid-zinc Oxide-ginsenoside Rh2 Nanoparticles and Their Potential Caspase-9 Apoptotic Mechanism Towards Cancer Cell Lines" Yeon Ju Kim; Haribalan Perumalsamy; Verónica Castro-Aceituno; Donghyuk Kim; Josua Markus, Seungah Lee; Sung Kim; Ying Liu; Deok Chun Yang, International Journal of Nanomedicine, 14, 8195-8208 (2019).
"Plasmonic Nanostructure-based Bioimaging and Detection Techniques at Single-Cell Level" Seungah Lee*; Yucheng Sun; Yingying Cao; Seong Ho Kang, Trac Trends in Analytical Chemistry, 117, 58-68 (2019).
"Plasmon-amplified Endogenous Fluorescence Nanospectroscopic Sensor based on Inherent Elastic Scattering for Ultra-trace Ratiometric Detection of Capsaicinoids" Suresh Kumar Chakkarapani; Seungah Lee; Boyeon Park; Hye-Young Seo; Seong Ho Kang, ACS Sens. 4, 953-960 (2019).
"Green Synthesis of Gold Nanoparticles using Euphrasia officinalis Leaf Extract to Inhibit Lipopolysaccharide-induced Inflammation Through NF-κB and JAK/STAT Pathways in RAW 264.7 Macrophages" Ying Liu; Senghyun Kim; Yeon Ju Kim; Haribalan Perumalsamy; Seungah Lee; Eunson Hwang; Tae-Hoo Yi, International Journal of Nanomedicine, 14, 2945-2959 (2019).
"Development of Lactobacillus kimchicus DCY51T-Mediated Gold Nanoparticles for Delivery of Ginsenoside Compound K: In Vitro Photothermal Effects and Apoptosis Detection in Cancer Cells" Yeon-Ju Kim; Haribalan Perumalsamy; Josua Markus; Sri Renukadevi Balusamy; Chao Wang; Seong Ho Kang; Seungah Lee; Sang Yong Park; Sung Kim; Verónica Castro-Aceituno; Seung Hyun Kim; Deok Chun Yang, Artificial Cells, Nanomedicine, and Biotechnology 47, 30-44 (2019).
"Three Dimensional Orientation of Anisotropic Plasmonic Aggregates at Intracellular Nuclear Indentation Sites by Integrated Light Sheet Super-Resolution Microscopy" Suresh Kumar Chakkarapani; Yucheng Sun; Seungah Lee; Ning Fang; Seong Ho Kang, ACS Nano 12, 4156−4163 (2018).
"One-Shot Dual-Code Immunotargeting for Ultra-Sensitive TNF-a Nanosensors by 3D Enhanced Dark-Field Super-Resolution Microscopy" Soyeong Ju*; Seungah Lee*; Suresh Kumar Chakkarapani; Kyungsoo Kim; Hyunung Yu; Seong Ho Kang Analytical Chemistry 90, 5100−5107 (2018).
"Supersensitive Single-particle Plasmonic Scattering-based Cancer Antigen 125 Nanoimmunosensor by Enhanced Dark-field Microscopy with Dual-detection Mode" S. Ju; S. K. Chakkarapani; S. Lee; S.H. Kang, Sens. Actuator B-Chem. (2017).
"Quality and Freshness of Human Bone Marrow-derived Mesenchymal Stem Cells Decrease Over Time after Trypsinization and Storage in Phosphate-buffered Saline" Tae Hwan Shin*; Seungah Lee*; Ki Ryung Choi; Da Yeon Lee; Yong Man Kim; Man Jeong Paik; Chan Seo; Suk Kang; Moon Suk Jin; Tae Hyeon Yoo; Seong Ho Kang; Gwang Lee, Sci. Rep. 7, Article number: 1106, doi:10.1038/s41598-017-01315-0 (2017).
"Optical Super-Resolution Imaging of Surface Reactions" T. Chen; B. Dong; K. Chen; F. Zhao; S. Lee; P. Zhang; S.H. Kang; J.W. Ha; W. Xu; N. Fang, Chem. Rev. 117, 7510-7537 (2017).
"Direct Quantitative Screening of Influenza A Virus without DNA Amplification by Single-particle Dual-mode Total Internal Reflection Scattering" S. Lee*; S.K. Chakkarapani; E. S. Yeung; S.H. Kang, Biosensors and Bioelectronics 87, 842–849 (2017).
"Ultrasensitive Detection of Alpha-fetoprotein by Total Internal Reflection Scattering-based Super-resolution Microscopy for Super-localization of Nano-immunoplasmonics" S. Ahn; P. Zhang; H. Yu; S. Lee; S.H. Kang, DOI: 10.1021/acs.analchem.6b03069, Anal. Chem. 88, 11070-11076 (2016).
"Augmented 3D Super-resolution of Fluorescence-free Nanoparticles Using Enhanced Dark-field Illumination Based on Wavelength-modulation and a Least-cubic Algorithm" P. Zhang; K. Kim; S. Lee; S.K. Chakkarapani; N. Fang; S.H. Kang, Scientific Reports 6, 2863; doi: 10.1038/srep32863 (2016).
"Quantitative Nanoimmunosensor based on Dark-field Illumination with Enhanced Sensitivity and On-off Switching using Scattering Signals" Seungah Lee*; He Nan; Hyunung Yu; Seong Ho Kang, Biosensors and Bioelectronics 79, 709-714 (2016).
"Real-time Intracellular Mg2+ Signaling and Wave Propagation by Subdiffraction-Limit Super-Resolution Microscopy" Suresh Kumar Chakkarapani; Seungah Lee; Gwang Lee; Seong Ho Kang, Bull. Korean Chem. Soc. 36, 2589-2595 (2015). *This article was selected as the Cover Article.
"Super-resolution of Fluorescence-free Plasmonic Nanoparticles using Enhanced Dark-field Illumination based on Wavelength-modulation" Peng Zhang; Seungah Lee; Hyunung Yu; Ning Fang; S.H. Kang, Scientific Reports 5, 11447; doi: 10.1038/srep11447 (2015).
"Plasmonic Metal Scattering Immunoassay by Total Internal Reflection Scattering Microscopy with Nanoscale Lateral Resolution" Seungah Lee*; Hyunung Yu; Seong Ho Kang, Chem. Commun., 51, 945-947 (2015).
"Ultra-sensitive Plasmonic Nanometal Scattering Immunosensor Based on Optical Control in Evanescent Field Layer" Seungah Lee*; Guenyoung Park; Suresh Kumar Chakkarapani; Seong Ho Kang, Biosensors and Bioelectronics 63, 444-449 (2015).
"Fluorescent-free Detection on Nanobiochips based on Wavelength-Dependent Single Plasmonic Nanoparticles by Differential Interference Contrast Microscopy" Seungah Lee*; Seong Ho Kang, Biosensors and Bioelectronics 60, 45-51 (2014).
"Selective Fluorescence and Fluorescence-Free Detection of Single Biomolecules on Nanobiochip" Seungah Lee*; Seong Ho Kang, J. Biomed. Nanotechnol. 10, 2620-2640 (2014).
"Selective Fluorescent-free Detection of Biomolecules on Nanobiochips by Wavelength Dependent-enhanced Dark Field Illumination" Seungah Lee*; Hyunung Yu; Seong Ho Kang, Chem. Commun. 49, 8335-8337 (2013).
"Single C-Reactive Protein Molecule Detection on a Gold-Nanopatterned Chip Based on Total Internal Reflection Fluorescence" Yunmi Heo; Seungah Lee; Sang-Won Lee; Seong Ho Kang, Bull. Korean Chem. Soc. 34, 2725-2730 (2013).
"Gold-Nanopatterned Single Interleukin-6 Sandwich Immunoassay Chips with Zeptomolar Detection Capability Based on Evanescent Field-enhanced Fluorescence imaging" Seungah Lee*; Seong Ho Kang, Analyst 138 (12), 3478-3482 (2013).
"Single-Molecule DNA Digestion in Various Alkanethiol-Functionalized Gold Nanopores" Seungah Lee*; Seong Ho Kang, Talanta 107, 297-303 (2013).
"Quenching Effect on Gold Nano-Patterned Cardiac Troponin I Chip by Total Internal Reflection Fluorescence Microscopy" Seungah Lee*; Seong Ho Kang, Talanta 104, 32-38 (2013).
"Single-Molecule Sandwich Immunoassay for Quantification of Alpha-Fetoprotein Based on Evanescent Field-Enhanced Fluorescence Imaging" Seungah Lee*; Seong Ho Kang, Journal of Nanomaterials 2012, Article ID 582531, 7 (2012).
"Wide-Range Quantification of Human Thyroid-Stimulating Hormone Using Gold-Nanopatterned Single-Molecule Sandwich Immunoassay Chip" Seungah Lee*; Seong Ho Kang, Talanta 99, 1030-1034 (2012).
"Photoswitchable Fluorescent Diarylethene in a Turn-on Mode for Live Cell Imaging" Shi-Chong Pang; Hyesook Hyun; Seungah Lee; Daeun Jang; Min Jae Lee; Seong Ho Kang; Kwang-Hyun Ahn, Chem. Commun. 48, 3745-3747 (2012).
"Integrated Optical Molecular Imaging System for Four-Dimensional Real-Time Detection in Living Single Cells" Seungah Lee*; Seong Ho Kang, Biosensors and Bioelectronics 31, 393-398 (2012).
"Enzyme Digestion of Entrapped Single-DNA Molecules in Nanopores" Seungah Lee*; Seong Ho Kang; Edward S. Yeung, Talanta 85, 2135-2141 (2011).
"Native and Fluorescent Dye-Dependent Single-DNA Molecule Microchip Dynamics as Measured by Differential Interference Contrast Microscopy" Doori Oh; Seungah Lee; Seong Ho Kang, Chem. Commun. 47, 9137-9139 (2011).
"Digestion of Individual DNA Molecules by Lambda-Exonuclease at Liquid-Solid Interface" Seong Ho Kang; Seungah Lee; Edward S. Yeung, Analyst 135, 1759-1764 (2010).
"Ultra-Sensitive Detection of TNF-α on Gold Nano-Patterned Protein Chip Formed via E-Beam Nanolithography by Total Internal Reflection Fluorescence Microscopy" Kyuseo Lee; Seungah Lee; Hyunung Yu; Seong Ho Kang, Journal of Nanoscience and Nanotechnology 10, 3228-3231 (2010).
"Detection of Single Enzyme Molecules Inside Nanopores on the Basis of Chemiluminescence" Seong Ho Kang; Seungah Lee; Edward S. Yeung, Angewandte Chemie International Edition 49, 2603-2606 (2010); Angewandte Chemie 122, 2657-2660 (2010).
"Real-Time Observations of Intracellular Mg2+ Signaling and Waves in Single Living Ventricular Myocyte Cell" Seungah Lee*; Hee Gu Lee; Seong Ho Kang, Analytical Chemistry 81, 538-542 (2009).
"An Ultra-Sensitive Nanoarray Chip Based on Single-Molecule Sandwich Immunoassay and TIRFM for Protein Detection in Biologic Fluids" Seungah Lee*; Nam-Pyo Cho; Jung Dong Kim; Hyungil Jung; Seong Ho Kang, Analyst 134, 933-938 (2009).
"Quantitative Analysis of Human Serum Leptin using a Nanoarray Protein Chip Based on Single-Molecule Sandwich Immunoassay" Seungah Lee*; Shinae Lee; Young-Ho Ko; Hyungil Jung; Jung Dong Kim; Joon Myong Song; Jaebum Choo; Seong Ho Kang, Talanta 78, 608-612 (2009).
"Dual-Color Prism-Type TIRFM System for Direct Detection of Single-Biomolecules on Nanoarray Biochip" Seungah Lee*; Bong Hyun Chung; Seong Ho Kang, Current Applied Physics 8, 700-705 (2008).
"Extra- and Intranuclear Dynamics and Distribution of Modified-PAMAM Polyplexes in Living Cells: A Single-Molecule Analysis" Seungah Lee*; Kihoon Nam; Jong-Sang Park; Joon Sig Choi; Seong Kug Eo; Dong Jin Yoo; Seong Ho Kang, Bulletin of the Korean Chemical Society 29, 1565-1568 (2008).
"Dexamethasone-Conjugated Low Molecular Weight Polyethylenimine as a Nucleus-Targeting Lipopolymer Gene Carrier" Yun Mi Bae; Hye Choi; Seungah Lee; Seong Ho Kang; Young Tae Kim; Kihoon Nam; Jong Sang Park; Minhyung Lee; Joon Sig Choi, Bioconjugate Chemistry 18, 2029-2036 (2007).
"Combination of DIC with Prism-Type Total Internal Fluorescence Microscope for Direct Observation of PAMAM Dendrimer Nanoparticle as a Gene Delivery in Living Human Cells" Seungah Lee*; Joon Sig Choi; Seong Ho Kang, Journal of Nanoscience and Nanotechnology 7, 3689-3694 (2007).
"Atypical Mobilities of Single Native DNA Molecules in Microchip Electrophoresis Revealed by Differential Interference Contrast Microscopy" Seong Ho Kang; Seungah Lee; Edward S. Yeung, Electrophoresis 27, 4149-4157 (2006).
"Differential Interference Contrast Microscopy for Real-Time Dynamics and Manipulation of Single Cells in Microchannels" Seungah Lee*; Youngseong Kim; Seong Ho Kang, Microchemical Journal 80, 107-112 (2005).
"Direct Observation of Single Native DNA Molecules in a Microchannel by Differential Interference Contrast Microscopy" Seong Ho Kang; Seungah Lee; Edward S. Yeung, Analytical Chemistry 76, 4459-4464 (2004).