Publications

Before 2025.07

List of first authorship research publications (*co-first)

Chung C*, Yang X*, et al., Gleeson JG. Cell-type-resolved mosaicism reveals the clonal dynamics of the human forebrain (2024) Nature, 629:384-392

Chung C*, Yang X*, et al., Gleeson JG. Comprehensive multi-omic profiling of somatic mutations in malformations of cortical development. (2023) Nat. Genet., 55:209-220 (Cover selected)

Chung C*, Ha S*, et al., Kim E. Early correction of NMDAR function improves autistic-like behaviors in adult Shank2–/– mice. (2019). Biol Psychiatry, 85:534-543 (Selected as Priority Communications)

Kim R*, Kim J*, Chung C*, et al., Kim E. (2018). Cell type-specific Shank2 deletion in mice leads to differential synaptic and behavioral phenotypes. J Neurosci, 38(17):4076-4092

Review publication

Chung C, Girgiss J, Gleeson JG. A comparative view of human and mouse telencephalon inhibitory neuron development. (2025) Development, 152(1):dev204306

Chung C, Yang X, Gleeson JG. Post-zygotic brain mosaicism as a result of partial reversion of pre-zygotic aneuploidy. (2023) Nat Genet, 55,1784-1785

Chung C, Shin W, Kim E. Early and late corrections in mouse models of autism spectrum disorders. (2022) Biol. Psychiatry, 91(11):934-944

List of co-authorship and group-authorship research publications

Jang DC, Kim SY, Kim WS, Jung H, Chung C, et al., Asymmetric distribution of mitochondrial Ca2+ regulators specifies compartment-specific mitochondrial function and neuronal development (2025) bioRxiv doi.org/10.1101/2025.06.23.660978

Maury EA et al., Brain Somatic Mosaicism Network, Park PJ, Akbarian S, Brennand K, Reilly S, Lee EA, Sunyaev SR, Walsh CA, Chess A. Somatic mosaicism in schizophrenia brains reveals prenatal mutational processes. (2024) Science, 386(6718):217-224

Vong KI, Alvarez YD, Noel G, Barton ST, Chung C et al., Joseph G Gleeson. Genomic mosaicism reveals developmental organization of trunk neural crest-derived ganglia (2024) bioRxiv doi: 10.1101/2024.09.25.615004

Sun C, Kathuria K, Emery SB, Kim B, Burbulis IE, Shin JH, Brain Somatic Mosaicism Network et al., Michael J McConnell. Mapping recurrent mosaic copy number variation in human neurons (2024) Nat. Commun., 15:4220

Garrison MA et al., BSMN Consortium. Genomic data resources of the Brain Somatic Mosaicism Network for neuropsychiatric diseases. (2023) Scientific Data, 10:813

Maury EA, et al., Brain Somatic Mosaicism Network, Sebat J, Lee EA, Walsh CA. Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions. (2023) Cell genomics, 3:100356

Yang X, Xu X, Breuss MW, Antaki D, Ball LL, Chung C, et al., Gleeson JG. Control-independent mosaic single nucleotide variant detection with DeepMosaic (2023) Nat. Biotechnol., DOI:10.1038/s41587-022-01559-w

Bae T*, Fasching L*, Wang Y*, Shin JH*, et al ., Brain Somatic Mosaicism Network, Urban A, Leckman JF, Weinberger DR, Vaccarino FM# Abyzov A#. Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability. (2022) Science, 377(6605):511-517

Breuss MW, Yang X, Schlachetzki JCM, Antaki D, Lana AJ., Xu X, Chung C, et al., Glass CK, Gleeson JG. Somatic mosaicism reveals clonal distributions of neocortical development. (2022) Nature, 604:689-696

Chai G, Szenker-Ravi E, Chung C, et al., Gleeson JG et al. A human pleiotropic multiorgan condition caused by deficient Wnt secretion (2021) New Eng J of Med, 385(14):1292-1301

Yoo Y, Lee S, Kim W, Kim H, Chung C, Ha S, Kang H, Kim E. Early chronic memantine treatment-induced transcriptomic changes in wild-type and Shank2-mutant mice. (2021) Front Mol Neurosci, 14:712576

Lee E, Lee S, Shin JJ, Choi W, Chung C, et al., Park JM#, Jung MW#, Paik S#, Kim E#. Excitatory synapses and gap junctions cooperate to improve Pv neuronal burst firing and cortical social cognition in Shank2-mutant mice (2021) Nat Commun,12:5116

Jung H, Park H, Choi Y, Kang H, Lee E, Kweon H, Roh JD, Ellegood J, Choi W, Kang J, Rhim I, Choi SY, Bae M, Kim SG, Lee J, Chung C, et al., Kim E. (2018). Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice. Nat Neurosci, 21:1218-1228

Li Y, Kim R, Cho YS, Song WS, Kim D, Kim K, Roh JD, Chung C, et al., Kim E. (2018). Lrfn2-mutant mice display suppressed synaptic plasticity and inhibitory synapse development and abnormal social communication and startle response. J. Neurosci, 38(26):5872-5887.

Ha S, Lee D, Cho YS, Chung C, et al., Tanaka-Yamamoto K#, and Kim E#. (2016). Cerebellar Shank2 regulates excitatory synapse density, motor coordination, and specific repetitive and anxiety-like behaviors. J Neurosci, 36(48):12129-12143.

Lee EJ, Lee H, Huang TNE, Chung C, et al., Hsueh YP#, and Kim E#. (2015). Trans-synaptic zinc mobilization improves social interaction in two mouse models of autism through NMDAR activation. Nat Commun, 6:7168.

Lee J, Chung C, et al., Kim E. (2015). Shank3-mutant mice lacking exon 9 show altered excitation/inhibition balance, enhanced rearing, and spatial memory deficit. Front Cell Neurosci, 9:94.

Won H, Lee HR, Gee HY, Mah W, Kim JI, Lee J, Ha S, Chung C, et al., Kaang BK#, Lee MG#, and Kim E#. (2012). Autistic-like social behavior in Shank2-mutant mice improved by restoring NMDA receptor function. Nature 486:261-5.