Development of novel payloads and their application to antibody-drug conjugates (ADCs) and related drug conjugates, including small molecule-drug conjugates and peptide-drug conjugates
Design and synthesis of a novel ADC linker platform optimized for phenolic payloadsÂ
Design and synthesis of first-in-class kinase inhibitors (oncology and non-oncology)
Construction of DNA-encoded library and development of new DNA-compatible reactions