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This event is supported by NIHR Cambridge Biomedical Research Centre (NIHR203312).
Friday, June 14 2024
Friday, June 14 2024
Registration 9:15 - 9:45
09:15 - 09:45
Meet and Greet
Meet and Greet
09:45 - 10:00
Welcome opening session
Welcome opening session
10:00 - 10:55
Opportunity and challenges in the study of T cell receptor repertoires
Opportunity and challenges in the study of T cell receptor repertoires
Benny Chain - Professor of Immunology, UCL
Coffee Break 10:55 - 11:10
11:10 - 11:45
Building the next generation of language models for antibody discovery
Building the next generation of language models for antibody discovery
Jinwoo Leem - Director of Machine Learning, Alchemab
11:45 - 11:55
Assessing the Data Landscape of MHC:Peptide:TCR Interactions: What We Know and What We Lack
Assessing the Data Landscape of MHC:Peptide:TCR Interactions: What We Know and What We Lack
Christopher Thorpe - ARISE fellow, EBI
11:55 - 12:20
Flash talks
Flash talks
Mohammad Sharif: CELLeBT: a tool to explore physical B cell-T cell clonal interactions through single-cell multi-omics
Chloe Admane & Elena Winheim: Prenatal skin atlas reveals macrophage regulation of human prenatal skin angiogenesis
Ioannis Sarropoulos: Dissecting the immune reconstitution after thymus transplantation, one cell at a time
Xin Ge: Single-cell RNA sequencing reveals age-associated changes in gp38+ CD31- lymph node stromal cells upon vaccination
Anna Lorenc: Synergistic imprint of HLA alleles predisposing to type I diabetes on TCR repertoire of T helper cells
Lunch break and posters 12:20 - 13:20
13:20 - 13:45
Flash talks
Flash talks
Yunguan Fu: Diffusion Model for Protein Structures
Catherine Sutherland: Immune repertoire dynamics following B cell depletion therapy in systemic lupus erythematosus patients
Arin Wongprommoon: Effect of diabetes on host gene expression and transcript splicing responses to melioidosis in Northeast Thailand
Elena Lukyanova: NUDCD3 deficiency disrupts V(D)J recombination to cause SCID and Omenn syndrome
13:45 - 14:10
Combining single-cell transcriptomics and BCR repertoires to understand the dynamics of B cell maturation
Combining single-cell transcriptomics and BCR repertoires to understand the dynamics of B cell maturation
Joseph Ng - Research fellow, UCL
14:10 - 14:35
Clarity through complexity: Decoding human immunity using single-cell omics
Clarity through complexity: Decoding human immunity using single-cell omics
Lucy C. Garner - Postdoctoral scientist, Oxford Uni.
14:35 - 15:00
Do protein structure prediction tools extrapolate?
Do protein structure prediction tools extrapolate?
Alexander Greenshields Watson - Senior Postdoctoral researcher, Oxford Uni.
Coffee break 15:00 - 15:20
15:20 - 16:00
Using antibodies to understand polygenic susceptibility to infection and HLA
Using antibodies to understand polygenic susceptibility to infection and HLA
Alexander Mentzer - PI in infection and immunogenetics, Oxford Uni.
16:00 - 16:30
Panel discussion and Closing session
Panel discussion and Closing session
Deborah Dunn-Walters - Professor of Immunology, Associate Dean Research and Innovation, University of Surrey
Lorenz Kretschmer - Postdoctoral scientist at Teichmann group, Sanger Institute
Chris Thorpe - ARISE fellow, EBI
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