Select publications (full list of publications at https://www.ncbi.nlm.nih.gov/myncbi/1HKEcjfIND_kd/bibliography/public/):
Slomnicki LP, Armstrong CD, Morehouse JR, Andres K, Musiek ES, Ohri SS, Hetman M. Conditional deletion of Bmal1 modestly alters acute pathology without affecting functional recovery after contusive spinal cord injury. Neurosci Lett. 2026 Aug 11;885:138707. doi: 10.1016/j.neulet.2026.138707. Epub ahead of print. PMID: 42580622; PMCID: PMC13526234.
Slomnicki LP, Owens RL, Hodges ER, McNeely J, Burke DA, Chariker JH, Rouchka EC, Ohri SS, Ding D, Hetman M. Exacerbation of hemorrhagic stroke and impaired hemostasis in mice deficient of the integrated stress response kinase heme-regulated inhibitor. Brain Circ. 2025 Jul 2;12(2):133-143. doi:10.4103/bc.bc_163_24. PMID: 42111301; PMCID: PMC13152244.
Slomnicki LP, Hodges E, Armstrong C, Morehouse J, Burke D, Ohri SS, Burris TP, Hetman M. Limited effects of the REV-ERB agonist SR9009 after mouse spinal cord contusion: Reduced acute pathology with unaffected functional recovery and chronic white matter loss. Neurosci Lett. 2026 Jan 1;870:138443. doi:10.1016/j.neulet.2025.138443. Epub 2025 Nov 12. PMID: 41232745; PMCID: PMC12809868.
Saraswat Ohri S, Myers SA, Rood B, Brown BL, Chilton PM, Slomnicki L, Liu Y, Wei GZ, Andres KR, Mohan D, Howard RM, Whittemore SR, Hetman M. Reduced White Matter Damage and Lower Neuroinflammatory Potential of Microglia and Macrophages in Hri/Eif2ak1-/- Mice After Contusive Spinal Cord Injury. Glia.2025 May;73(5):1004-1021. doi: 10.1002/glia.24669. Epub 2025 Jan 6. PMID:39760211.
Saraswat Ohri S, Forston MD, Myers SA, Brown BL, Andres KR, Howard RM, Gao Y, Liu Y, Cavener DR, Hetman M, Whittemore SR. Oligodendrocyte-selective deletion of the eIF2α kinase Perk/Eif2ak3 limits functional recovery after spinal cord injury. Glia. 2024 Jul;72(7):1259-1272. doi: 10.1002/glia.24525. Epub 2024 Apr 8. PMID: 38587137.
Ugiliweneza B, Wang D, Rood B, Boakye M, Castillo C, Hetman M. Increased Incidence of Depression and Chronic Pain in Traumatic Spinal Cord InjuryPatients With Pre-Injury Alcohol Use Disorder: Longitudinal Analysis of Insurance Claim Database. Neurotrauma Rep. 2024 Jan 12;5(1):28-36. doi:10.1089/neur.2023.0096. PMID: 38249325; PMCID: PMC10797174.
Gao Y, Slomnicki LP, Kilanczyk E, Forston MD, Pietrzak M, Rouchka EC, Howard RM, Whittemore SR, Hetman M. Reduced Expression of Oligodendrocyte Linage-Enriched Transcripts During the Endoplasmic Reticulum Stress/Integrated Stress Response. ASN Neuro. 2024;16(1):2371162. doi: 10.1080/17590914.2024.2371162. Epub 2024 Jul 16. PMID: 39024571; PMCID: PMC11262469.
Forston MD, Wei GZ, Chariker JH, Stephenson T, Andres K, Glover C, Rouchka EC, Whittemore SR, Hetman M. Enhanced oxidative phosphorylation, re-organized intracellular signaling, and epigenetic de-silencing as revealed by oligodendrocyte translatome analysis after contusive spinal cord injury. Sci Rep. 2023 Dec 1;13(1):21254. doi: 10.1038/s41598-023-48425-6. PMID: 38040794; PMCID: PMC10692148.
Ugiliweneza B, Boakye M, Ohri SS, Whittemore SR, Hetman M. Associations Between Diurnal Timing of Spinal Cord Injury and Its Etiology and Co-Morbidities. J Neurotrauma. 2023 Sep;40(17-18):1959-1969. doi:10.1089/neu.2022.0411. PMID: 36628481; PMCID: PMC10460688.
Gao Y, Wei GZ, Forston MD, Rood B, Hodges ER, Burke D, Andres K, Morehouse J, Armstrong C, Glover C, Slomnicki LP, Ding J, Chariker JH, Rouchka EC, Saraswat Ohri S, Whittemore SR, Hetman M. Opposite modulation of functional recovery following contusive spinal cord injury in mice with oligodendrocyte-selective deletions of Atf4 and Chop/Ddit3. Sci Rep. 2023 Jun 6;13(1):9193. doi:10.1038/s41598-023-36258-2. PMID: 37280306; PMCID: PMC10244317.
Saraswat Ohri S, Andres KR, Howard RM, Brown BL, Forston MD, Hetman M, Whittemore SR. Acute Pharmacological Inhibition of Protein Kinase R-Like Endoplasmic Reticulum Kinase Signaling After Spinal Cord Injury Spares Oligodendrocytes and Improves Locomotor Recovery. J Neurotrauma. 2023 May;40(9-10):1007-1019. doi: 10.1089/neu.2022.0177. Epub 2023 Jan 25. PMID: 36503284; PMCID: PMC10162120.
Whittemore SR, Saraswat Ohri S, Forston MD, Wei GZ, Hetman M. The Proteostasis Network: A Global Therapeutic Target for Neuroprotection after Spinal Cord Injury. Cells. 2022 Oct 22;11(21):3339. doi: 10.3390/cells11213339. PMID: 36359735; PMCID: PMC9658791.
Hetman M, Slomnicki LP, Hodges ER, Saraswat Ohri S, Whittemore SR. Role of circadian rhythms in pathogenesis of acute CNS injuries: Insights from experimental studies. Exp Neurol. 2022 Jul;353:114080. doi:10.1016/j.expneurol.2022.114080. Epub 2022 Apr 9. PMID: 35405120; PMCID: PMC10260623.
Slomnicki LP, Wei G, Burke DA, Hodges ER, Myers SA, Yarberry CD, Morehouse JR, Whittemore SR, Saraswat Ohri S, Hetman M. Limited changes in locomotor recovery and unaffected white matter sparing after spinal cord contusion at different times of day. PLoS One. 2021 Nov 23;16(11):e0249981. doi:10.1371/journal.pone.0249981. PMID: 34813603; PMCID: PMC8610253.
Wei GZ, Saraswat Ohri S, Khattar NK, Listerman AW, Doyle CH, Andres KR, Karuppagounder SS, Ratan RR, Whittemore SR, Hetman M. Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery. PLoS One. 2021 Apr 5;16(4):e0249591. doi:10.1371/journal.pone.0249591. PMID: 33819286; PMCID: PMC8021188.
Saraswat Ohri S, Burke DA, Andres KR, Hetman M, Whittemore SR. Acute Neural and Proteostasis Messenger Ribonucleic Acid Levels Predict Chronic Locomotor Recovery after Contusive Spinal Cord Injury. J Neurotrauma. 2021 Feb;38(3):365-372. doi: 10.1089/neu.2020.7258. Epub 2020 Nov 10. PMID: 33076743; PMCID: PMC7826426.
Saraswat Ohri S, Howard RM, Liu Y, Andres KR, Shepard CT, Hetman M, Whittemore SR. Oligodendrocyte-specific deletion of Xbp1 exacerbates the endoplasmic reticulum stress response and restricts locomotor recovery after thoracic spinal cord injury. Glia. 2021 Feb;69(2):424-435. doi:10.1002/glia.23907. Epub 2020 Sep 14. PMID: 32926479; PMCID: PMC8931742.
Slomnicki LP, Myers SA, Saraswat Ohri S, Parsh MV, Andres KR, Chariker JH, Rouchka EC, Whittemore SR, Hetman M. Improved locomotor recovery after contusive spinal cord injury in Bmal1-/- mice is associated with protection of the blood spinal cord barrier. Sci Rep. 2020 Aug 26;10(1):14212. doi:10.1038/s41598-020-71131-6. PMID: 32848194; PMCID: PMC7450087.