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addition to the treatment plan for some patients. Additional information about the different kinds of transplants that are available for some HL patients start on the next page. Talk to your doctor about whether a stem cell transplant is a treatment option for you. HL The Lymphoma Guide I page 19 You can view, print or order the free LLS publication Blood and Marrow Stem Cell Transplantation at www.LLS.org/resourcecenter or contact our Information Specialists for a copy. Want more information? Autologous Stem Cell Transplantation. Autologous transplantation is more frequently used than allogeneic transplantation for Hodgkin lymphoma patients. The goal of autologous stem cell transplantation is to help the body start a new supply of blood cells after high-dose chemotherapy. With an autologous transplant { The patient’s own stem cells are collected from the patient’s blood or marrow and stored after the first cycles of drug therapy are completed. { The patient is then given high-dose chemotherapy to kill the lymphoma cells. This treatment also kills normal stem cells in the marrow. { The last step is to infuse the stem cells back into the patient through a central line. Allogeneic Stem Cell Transplantation. An allogeneic transplant is a treatment that uses stem cells from a donor. The donor may be a brother or sister. Or, the donor can be an unrelated person with stem cells that “match” the patient’s. Stem cells may also come from a cord blood unit (the blood in the umbilical cord after a baby’s birth). Allogeneic transplants may be done in the hospital. First, the patient is given high-dose chemotherapy and/or radiation therapy to kill the lymphoma cells in the body. Stem cells are collected from a donor. The donor stem cells are given to the patient through an intravenous (IV) line or central line. The donor stem cells go from the patient’s blood to the marrow and help start a new supply of red blood cells, white blood cells and platelets. HL page 20 I 800.955.4572 I www.LLS.org Reduced-intensity allogeneic stem cell transplantation (also called a nonmyeloablative transplant) uses lower doses of chemotherapy than a standard allogeneic transplant. Some older and sicker patients may be helped by this treatment. Talk to your doctor about whether stem cell transplantation is a treatment option for you. Childhood Hodgkin Lymphoma Children and teens with Hodgkin lymphoma should be treated at medical centers that have a pediatric oncology team. It is important for young adults and parents of children to talk to members of the oncology team about the { Stage of the disease { Type of Hodgkin lymphoma { Lab test results. Doctors use this information about the patient’s disease in order to determine the most effective therapy. Children and young adults with Hodgkin lymphoma are usually treated with combination chemotherapy, sometimes with the addition of radiation therapy to increase local control of the disease. See Pretreatment Considerations on page 11 and About Clinical Trials on page 34 for more information. HL The Lymphoma Guide I page 21 Part 3 Non-Hodgkin Lymphoma You can view, print or order the free LLS publication Non-Hodgkin Lymphoma at www.LLS.org/resourcecenter or contact our Information Specialists for a copy. Want more information? There are many types of non-Hodgkin lymphoma (NHL). Most people with NHL have a B-cell type of NHL (about 85 percent). The others have a T-cell type or an NK-cell type of lymphoma. NHL that is { Slow-growing is called indolent or low-grade { Fast-growing is called aggressive or high-grade. Talk to your doctor about the type of NHL that you have and your treatment choices.