Research perspectives

Exploring general developmental principles in vertebrates using small fish as models

We have been studying the mechanisms of body axis formation and organogenesis using small fish,  zebrafish (Danio rerio) and medaka (Oryzias latipes). Small fish are model vertebrates suitable for developmental genetics and experimental embryology because of the large number of mutants, and the ease of genetic and embryonic manipulation. Currently, we are focusing on left-right axis formation, somite differentiation, and otolith formation. We are also collaborating on the Medaka Genome Project to study the genome and epigenome evolution of vertebrates.