Overview
It is a form of electrical stimulation
Typically involves placing 4 electrode pads (2 pairs) onto the skin in a cross-cross pattern surrounding the treatment area
It is used to alleviate musculoskeletal pain, edema, and slightly stimulate muscles (which helps increase blood flow and thus promotes tissue healing)
ChiroEco. The guide to incorporating IFC therapy into your practice thumbnail image. ChiroEco website.
How it Works
Each pair of currents fire at a slightly different medium frequency and the currents intersect deep into the treatment area
The two currents intersecting creates a new, low-frequency current
Can be thought of as: medium frequency current A + medium frequency current B = therapeutic frequency C
Therapeutic frequency C has an irregular, uneven pattern (called a beat frequency) from the two different medium frequencies combining together, which helps prevent the body from becoming accustom to the stimulus, allowing the therapeutic effects of IFC to last longer
This low-frequency current stimulates tissues and nerves (sensory afferent neurons) in the treatment area leading to affects such as:
Blocking of pain signals from the brain (Gate Control Theory of Pain)
Stimulating release of endorphins (can help reduce pain)
Increased blood flow (promotes tissue healing)
Sensory afferent neurons are the first nerves that detect a stimulus and send it to the spinal cord to be sent up to the brain to be interpreted
The low-frequency current stimulates these neurons which will either block pain signals or stimulate release of endorphins (depending on which IFC machine settings are being used)
Why not just use a low frequency to begin with?
A low-frequency current does not go through the skin as easily and can be painful
Medium-frequency currents pass through the skin more easily and combine to produce a low-frequency deeper in the tissues
Machine Settings
Beat Frequency: The difference between the two medium-frequency currents (measured in Hertz/Hz)
Lower frequency between 2-10 Hz will induce the release of endorphins to help reduce pain
Higher frequency between 100-150 Hz will induce the blocking of pain signals to help reduce pain
One setting for pain reduction is not inherently "better" than the other - may require several trials with a patient and gathering their feedback to find what setting works best for managing their symptoms
Think of this as the rhythm/tempo in music
Intensity (amplitude): The strength of the electrical currents being delivered into the treatment area (which combine to form the therapeutic current (measured in milliamps/mA)
Controls how much of the current goes into the body
Is the only setting adjusted based on patient feedback
Should be slowly increased until the patient feels a strong but comfortable tingling sensation
Think of this as the volume in music
Duration: The amount of time the IFC machine is on
Treatment is usually between 10-15 minutes
Acute injuries can get desired effects in 5-10 minutes
Those with chronic pain may need to receive longer treatment time (20-30 minutes)
Because using IFC for long periods in the clinic isn’t always practical, it’s helpful to advocate for a home unit that insurance might cover
Sweep: Controls the variation of the beat frequency over time within a set range (referred to as beat low and beat high)
Is not a setting on every machine
This prevents nerve accommodation by constantly changing the stimulation frequency, helping maintain treatment effectiveness and patient comfort
If a machine has this setting and the recommended beat frequency settings mentioned above are being utilized, one would simply set the beat low to 2 Hz and the beat high to 10 Hz if you are attempting to release endorphins for pain management for example
Indications
Pain (acute or chronic)
Inflammation
Edema/swelling
Muscle spasms
Muscle weakness
Contraindications:
Arterial artery disease
Active infection
Deep vein thrombosis
Epilepsy
Hemorrhagic conditions or recent bleeding
Impaired sensation
Irritated skin
Pacemaker
Pregnancy
Tumor present in treatment area
However, generally IFC can still be used if these contraindications are not present in the upper extremity
Quiz Questions
How many electrodes are typically used during an IFC treatment?
A. 4
B. 2
C. 3
D. 6
What is the purpose of crossing two medium-frequency currents in IFC?
A. To decrease skin resistance
B. To deliver heat to the muscles
C. To create a therapeutic low-frequency current deeper in the tissues
D. To strengthen the affected muscles
Why is IFC preferred over applying a low-frequency current directly?
A. Low-frequency currents can cause muscle spasms
B. Medium-frequency currents pass through the skin more easily and are less painful
C. High-frequency is better for bone remodeling
D. Low-frequency causes vasodilation
What does a beat frequency of 2–10 Hz in IFC promote?
A. Muscle hypertrophy
B. Bone healing
C. Endorphin release for pain reduction
D. Scar remodeling
Which machine setting in IFC helps prevent nerve accommodation by varying the beat frequency over time?
A. Intensity
B. Volume
C. Sweep
D. Pulse width
Which of the following is a contraindication for using IFC?
A. Chronic pain
B. Muscle spasms
C. Joint stiffness
D. Presence of a pacemaker
What type of neurons are primarily stimulated by the low-frequency current in IFC therapy?
A. Motor efferent neurons
B. Sensory afferent neurons
C. Sympathetic neurons
D. Interneurons
What pain management theory is supported by IFC’s ability to block pain signals?
A. Gate Control Theory of Pain
B. Muscle Re-education Theory
C. Pythagorean Theorem
D. Reflex Arc Theory
What is a key advantage of using IFC over other forms of electrical stimulation?
A. It’s faster to apply
B. It penetrates deeper with less discomfort
C. It works without electrodes
D. It more effectively targets bone tissue
Quiz Answers
A
C
B
C
C
D
B
A
B
References
Interferential Current (IFC). (n.d.). Physio Montreal. http://www.physiomontreal.com/IFC.pdf
Interferential Therapy. (n.d.). Electrotherapy On The Web. https://www.electrotherapy.org/interferential
Rampazo, É. P., & Liebano, R. E. (2022). Analgesic effects of interferential current therapy: A narrative review. Medicina, 58(1), 141. https://doi.org/10.3390/medicina58010141