This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow's generation of life-saving cardiac devices.

N2 - This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow's generation of life-saving cardiac devices.


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AB - This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow's generation of life-saving cardiac devices.

Contains a companion CD with videos of the Visible Heart, a visualization of functional cardiac anatomy jointly developed by the University of Minnesota and the Cardiac Rhythm Management Division at Medtronic, Inc.

This chapter covers the internal and external anatomy and function of the heart, as well as its positioning within the thorax. Briefly, the heart is a muscular pump, located in the protective thorax, which serves two functions: (1) collect blood from the tissues of the body and pump it to the lungs; and (2) collect blood from the lungs and pump it to all the tissues of the body. The heart's two upper chambers (or atria) function primarily as collecting chambers, while two lower chambers (ventricles) are much stronger and function to pump blood. The right atrium and ventricle collect blood from the body and pump it to the lungs, and the left atrium and ventricle collect blood from the lungs and pump it throughout the body. There is a one-way flow of blood through the heart which is maintained by a set of four valves (tricuspid, bicuspid, pulmonary, and aortic). The tissues of the heart are supplied with nourishment and oxygen by a separate vascular supply committed only to the heart; the arterial supply to the heart arises from the base of the aorta as the right and left coronary arteries, and the venous drainage is via cardiac veins that return deoxygenated blood to the right atrium.

N2 - This chapter covers the internal and external anatomy and function of the heart, as well as its positioning within the thorax. Briefly, the heart is a muscular pump, located in the protective thorax, which serves two functions: (1) collect blood from the tissues of the body and pump it to the lungs; and (2) collect blood from the lungs and pump it to all the tissues of the body. The heart's two upper chambers (or atria) function primarily as collecting chambers, while two lower chambers (ventricles) are much stronger and function to pump blood. The right atrium and ventricle collect blood from the body and pump it to the lungs, and the left atrium and ventricle collect blood from the lungs and pump it throughout the body. There is a one-way flow of blood through the heart which is maintained by a set of four valves (tricuspid, bicuspid, pulmonary, and aortic). The tissues of the heart are supplied with nourishment and oxygen by a separate vascular supply committed only to the heart; the arterial supply to the heart arises from the base of the aorta as the right and left coronary arteries, and the venous drainage is via cardiac veins that return deoxygenated blood to the right atrium.

AB - This chapter covers the internal and external anatomy and function of the heart, as well as its positioning within the thorax. Briefly, the heart is a muscular pump, located in the protective thorax, which serves two functions: (1) collect blood from the tissues of the body and pump it to the lungs; and (2) collect blood from the lungs and pump it to all the tissues of the body. The heart's two upper chambers (or atria) function primarily as collecting chambers, while two lower chambers (ventricles) are much stronger and function to pump blood. The right atrium and ventricle collect blood from the body and pump it to the lungs, and the left atrium and ventricle collect blood from the lungs and pump it throughout the body. There is a one-way flow of blood through the heart which is maintained by a set of four valves (tricuspid, bicuspid, pulmonary, and aortic). The tissues of the heart are supplied with nourishment and oxygen by a separate vascular supply committed only to the heart; the arterial supply to the heart arises from the base of the aorta as the right and left coronary arteries, and the venous drainage is via cardiac veins that return deoxygenated blood to the right atrium.

This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart valve disease, and genomics-based tools and technology. Once again, a companion of supplementary videos offers unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the-art, the Handbook of Cardiac Anatomy, Physiology, and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to develop and implement tomorrow's generation of life-saving cardiac devices.

Many of the differences in cardiac anatomy between pigs and humans are the result of a quadruped compared with biped stance as well as the unusual conformation of the human thorax, which is dorsoventrally compressed, compared with the thorax of other mammals, which typically is laterally compressed. Consequently, the morphology and topography as well as the terminology of the thoracic organs differ between most mammals used in biomedical research and humans. As far as topography is concerned, the long axis of the swine heart tips forward, forming an acute angle to the vertical plane (Figure 1). Furthermore, the heart of these animals species are rotated counterclockwise compared with the human heart. As a result, the left ventricle and left atrium faces caudally, whereas the right atrium and ventricle are cranially situated (Figure 1). Due to the quadruped stance, the heart appears to be overhanging the thoracic cavity by its major vessels; therefore, venal drainage has a gravitational component. The orifices of the caval veins of pigs and other animals form an angle as they enter the right atrium, in contrast to the human caval veins, which are aligned along the same axis.8 Regarding terminology, the superior and inferior caval veins of humans are called the cranial and caudal caval veins in the majority of mammals used in biomedical research. An important difference is the presence of the left azygous vein in pigs, which drains directly into the coronary sinus; the human heart lacks this anatomic arrangement.50 In the swine heart, the right auricle has a narrow tubular appearance, compared with the triangular shape of that in humans. The number of orifices for the left atrium varies among mammals. In pigs the left atrium receives oxygenated blood from 2 pulmonary veins, in dogs from 5 or 6, and in humans from 4 or 5.25

Anatomy is one of the oldest branches of medicine, dating back as far as the 3rd century B.C. Throughout time, the discipline has been served well by a universal system for describing structures based on the anatomic position. Unfortunately, cardiac anatomy has been an outlier from this long-standing tradition. Cardiac anatomy has often been incorrectly described using confusing and inappropriate nomenclature. This is most likely due to the examination of the heart in the valentine position, in which the heart stands on its apex as opposed to how it is actually oriented in the body. The description of the major coronary arteries, such as the anterior descending and posterior descending, is attitudinally incorrect; as the heart is oriented in the body, the surfaces are actually superior and inferior. (Hill, 2015)

As the field of cardiac anatomy continues to play an important role in the practice of medicine and the development of medical devices, it benefits all involved to adopt commonly used terminology to describe the heart and its proper location in the body. Furthermore, it may be of great utility to describe the cardiac anatomy of major animal models using the same terminology as that of humans, at least when comparisons are being made between species. Finally, due to advances in 3D and 4D imaging and their growing use in the cardiac arena, a sound foundation of attitudinally correct terms will benefit everyone involved. 2351a5e196

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