Publications

Barthe, M.; Gillot, L.; Perdigon, L.; Jacobs, A.; Schoonbroodt, G.; Mauhin, P.; Bouhajja, E.; Osman-Ponchet, H. Topical Probiotic Formulation Promotes Rapid Healing in Dog Keratinocyte Cells: A Promising Approach for Wound Management. Int. J. Mol. Sci. 2023, 24, 12360. https://doi.org/10.3390/ijms241512360 

M Barthe, L Hertereau, N Lamghari, H Osman-Ponchet, VM Braud. Receptors and Cofactors That Contribute to SARS-CoV-2 Entry: Can Skin Be an Alternative Route of Entry?  Int. J. Mol. Sci. 2023, 24(7), 6253. https://doi.org/10.3390/ijms24076253 

M Barthe, JP Thénot, H Osman-Ponchet. Effect of UVB Radiation on the Expression of ABC and SLC Drug Transporters in Human Dermal Fibroblasts. Clin Exp Dermatol Ther, 2022,  7: 193. https://doi.org/10.29011/2575-8268.100193 

M Barthe,  C Bavoux, F Finot, I Mouche, C Cuceu-Petrenci, A Forreryd, A Chérouvrier Hansson, H Johansson, GF. Lemkine, JP Thénot,  H Osman-Ponchet. Safety Testing of Cosmetic Products: Overview of Established Methods and New Approach Methodologies (NAMs). Cosmetics, 2021, 8, (2), 50. https://www.mdpi.com/2079-9284/8/2/50/

F Endringer Pinto, C Bagger, G Kunze, N Joly‐Tonetti, JP Thénot, H Osman‐Ponchet, Christian Janfelt.  Visualization of penetration of topical antifungal drug substances through mycosis‐infected nails by matrix assisted laser desorption ionization mass spectrometry imaging. Mycoses, 2020, 63 (8), 869-875. https://doi.org/10.1111/myc.13103

M Ghannoum, L Long, G Kunze, M Sarkany, H Osman‐Ponchet. A pilot, layerwise, ex vivo evaluation of the antifungal efficacy of amorolfine 5% nail lacquer vs other topical antifungal nail formulations in healthy toenails. Mycoses, 2019, 62 (6), 494-501.  https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fmyc.12896

LA Clerbaux, A Paini, A Lumen, H Osman-Ponchet, AP Worth, O Fardel. Membrane transporter data to support kinetically-informed chemical risk assessment using non-animal methods: Scientific and regulatory perspectives. Environment international, 2019, 126, 659-671. https://www.sciencedirect.com/science/article/pii/S0160412018324930

AS Dugaret, B Bertino, B Gauthier, B Gamboa, M Motte, Y Rival, D Piwnica,  H Osman‐Ponchet,  V Bourdès,  J.J Voegel. An innovative method to quantitate tissue integration of hyaluronic acid-based dermal fillers.  Skin Research and Technology, 2018, 24 (3), 423-431. https://doi.org/10.1111/srt.12445

H Osman-Ponchet, M Alriquet, M Kouidhi, K Sevin, A Gaborit. Use of Microneedle Device to Enhance Dermal Absorption: Study on Ex Vivo Human Skin. J Dermat Cosmetol, 2018, 2 (2), 00032. http://dx.doi.org/10.15406/jdc.2018.02.00032

H Osman-Ponchet, A Gaborit, K Sevin, et al. Preteatment of skin using an abrasive skin preparation pad, a microneedling device or iontophoresis improves absorption of methyl aminolevulinate in ex vivo human skin. Photodiagnosis and Photodynamic Therapy , 2017, 20, 130-136.  http://dx.doi.org/10.1016/j.pdpdt.2017.09.006

H Osman-Ponchet, A Gaborit, M Kouidhi, S Anglars, et al. Comparison of the Effect of Skin Preparation Pads on Transepidermal Water Loss in Ex Vivo Human Skin.  Dermatology and Therapy, 2017,  7 (3), 407-415. http://dx.doi.org/10.1007/s13555-017-0193-2

H Osman-Ponchet, A Gaborit, JM Linget, CE Wilson. Expression of drug transporters in the human skin: comparison in different species and models and its implication for drug development.  ADMET and DMPK, 2017, 5 (2), 75-84. http://dx.doi.org/10.5599/admet.5.2.390

H Osman-Ponchet, K Sevin, A Gaborit, M Kouidhi, et al. Lack of effect of selected sunscreens applied on ex vivo human skin for 5-methyl-aminolevulinic acid penetration and protoporphyrin IX photoactivation. Photodiagnosis and photodynamic therapy, 2017, 17, 75-81. http://dx.doi.org/10.1016/j.pdpdt.2016.11.012

H Osman-Ponchet, K Sevin, A Gaborit, N Wagner, M Poncet. Fixed-combination gels of adapalene and benzoyl peroxide provide optimal percutaneous absorption compared to monad formulations of these compounds: results from two in vitro studies. Dermatology and therapy, 2017, 7 (1), 123-131. http://dx.doi.org/10.1007/s13555-016-0159-9

B Sigurgeirsson, MA Ghannoum, H Osman‐Ponchet, N Kerrouche. Application of cosmetic nail varnish does not affect the antifungal efficacy of amorolfine 5% nail lacquer in the treatment of distal subungual toenail onychomycosis: results of a randomised active-controlled study and in vitro assays. Mycoses , 2016, 59 (5), 319-326. http://dx.doi.org/10.1111/myc.12473

M Alriquet, K Sevin, A Gaborit, P Comby, B Ruty, H Osman-Ponchet. Characterization of SLC transporters in human skin. ADMET and DMPK , 2015, 3 (1.), 34-44. http://dx.doi.org/10.5599/admet.3.1.163

H Osman-Ponchet, A Boulai, M Kouidhi, K Sevin, M Alriquet, A Gaborit, et al. Characterization of ABC transporters in human skin. Drug Metabolism and Personalized Therapy, 2014, 29 (2), 91-100. http://dx.doi.org/10.1515/dmdi-2013-0042

J Lochman, T Kasparovsky, J Damborsky, H Osman, et al. Construction of Cryptogein Mutants, a Proteinaceous Elicitor from Phytophthora, with Altered Abilities To Induce a Defense Reaction in Tobacco Cells. Biochemistry, 2005, 44 (17), 6565-6572. http://dx.doi.org/10.1021/bi0502285

A Lancon, D Delma, H Osman, JP Thénot, B Jannin, N Latruffe. Human hepatic cell uptake of resveratrol: involvement of both passive diffusion and carrier-mediated process. Biochemical and biophysical research communications, 2004, 316 (4), 1132-1137. http://dx.doi.org/10.1016/j.bbrc.2004.02.164

H Osman, C Murigande, A Nadakal, AM Capponi. Repression of dax-1 and induction of sf-1 expression two mechanisms contributing to the activation of aldosterone biosynthesis in adrenal glomerulosa cells. Journal of Biological Chemistry , 2002, 277 (43), 41259-41267. http://dx.doi.org/10.1074/jbc.m206595200

GQ Ding, G Maume, H Osman, M Padieu, ML Milat, C Humbert, JP Blein, et al. Effects of 12 beticolins, Cercospora beticola toxins, on proliferation of ras-transformed adrenocortical cell. Acta pharmacologica Sinica, 2001, 22 (9), 769-776. https://serials.unibo.it/cgi-ser/start/en/spogli/df-s.tcl?prog_art=8455745&language=ENGLISH&view=articoli

H Osman, S Vauthrin, V Mikes, ML Milat, F Panabières, A Marais, et al. Mediation of elicitin activity on tobacco is assumed by elicitin-sterol complexes. Molecular Biology of the Cell, 2001, 12 (9), 2825-2834. http://dx.doi.org/10.1091/mbc.12.9.2825

H Osman, V Mikes, ML Milat, M Ponchet, D Marion, T Prange, BF Maume, et al. Fatty acids bind to the fungal elicitor cryptogein and compete with sterols. FEBS letters, 2001, 489 (1), 55-58. http://dx.doi.org/10.1016/s0014-5793(01)02078-6

JL Mazet, M Padieu, H Osman, G Maume, P Mailliet, N Dereu, et al. Combination of the novel farnesyltransferase inhibitor RPR130401 and the geranylgeranyltransferase‐1 inhibitor GGTI‐298 disrupts MAP kinase activation and G1‐S transition in Ki-Ras-overexpressing transformed adrenocortical cells. FEBS letters, 1999,  460 (2), 235-240. https://doi.org/10.1016/S0014-5793(99)01355-1

S Vauthrin, V Mikes, ML Milat, M Ponchet, B Maume, H Osman, JP Blein. Elicitins trap and transfer sterols from micelles, liposomes and plant plasma membranes. Biochimica et Biophysica Acta (BBA)-Biomembranes, 1999, 1419 (2), 335-342. http://dx.doi.org/10.1016/s0005-2736(99)00083-8

H Osman, JL Mazet, G Maume, BF Maume. Geranylgeranyl   as well as farnesyl moiety is transferred to Ras p21 overproduced in adrenocortical cells transformed by c-Ha-rasEJ oncogene. Biochemical and biophysical research communications, 1997, 231 (3), 789-792. http://dx.doi.org/10.1006/bbrc.1997.6183

G Descotes, H Osman, JF Gallas, E Penacchio, C Moreau. Functional, biochemical, and morphological hepatobiliary effects in rats chronically exposed to a steroidal antiandrogen. Toxicology and applied pharmacology, 1996, 137 (1), 23-33. http://dx.doi.org/10.1006/taap.1996.0053