Publications

Check out Guy's profile at Google Scholar, ResearchGate, PubMed, or Orchid

Improving optical sectioning with spinning disk structured illumination microscopy

Tristan C. Paul, Guy M. Hagen

Optics Express, 2023

Super-resolution imaging of neuronal structures with structured illumination microscopy

Tristan C. Paul, Karl A. Johnson, Guy M. Hagen

Bioengineering, 2023

Preprint on Biorxiv


Flexible multiplane structured illumination microscope with a four-camera detector

Karl A. Johnson, Daniel Noble, Rosa Machado, Tristan C. Paul, Guy M. Hagen

Photonics, 2022

Preprint on Biorxiv

Part of the Special Issue: Advances and Application of Super-resolution Optical Microscopy

Fluorescence microscopy datasets for training deep neural networks 

Guy M. Hagen, Justin Bendesky, Rosa Machado, TA Nguyen, T. Kumar, Jonathan Ventura 

GigaScience, 2021

All of the Raw and analyzed data is freely available on the Giga-Database!

Preprint on Biorxiv

Artifact-free whole-slide imaging with structured illumination microscopy and Bayesian image reconstruction

Karl Johnson, Guy M. Hagen

GigaScience, 2020

All of the Raw and analyzed data is freely available on the Giga-Database!

Preprint on Biorxiv

View the huge images with this awesome Interactive panorama viewer!

Self-supervised poisson-gaussian denoising

W. Khademi, S. Rao, C. Minnerath, Guy M. Hagen, Jonathan Ventura 

IEEE/CVF Winter Conference on Applications of Computer Vision 2021

Optical Imaging of Magnetic Particle Cluster Oscillation and Rotation in Glycerol

River Gassen, Dennis Thompkins, Austin Routt, Philippe Jones, Meghan Smith, William Thompson, Paul Couture, Dmytro A. Bozhko, Zbigniew Celinski, Robert E. Camley, Guy M. Hagen, Kathrin Spendier 

Journal of Imaging 2021

Fast Switching Dual-Frequency Nematic Liquid Crystal Tunable Filters

Olha Melnyk, Reed Jones, Rair Macêdo, Yuriy Garbovskiy, Guy Hagen, Anatoliy V Glushchenko, Kathrin Spendier, Robert E Camley 

ACS photonics 2021 

Optimization of laser deposited silver nanoparticle substrates for surface-enhanced Raman spectroscopy

Tristan C Paul, Guy M Hagen, Anatoliy O Pinchuk, Kelly L McNear 

Nanotechnology, 2022

Imaging Membrane Curvature inside a FcεRI-Centric Synapse in RBL-2H3 Cells Using TIRF Microscopy with Polarized Excitation 

Rosa Machado, Justin Bendesky, Madison Brown, Kathrin Spendier, Guy M Hagen 

Journal of Imaging, 2019

Preprint on Biorxiv

Super-resolution fight club: assessment of 2D and 3D single-molecule localization microscopy software

Daniel Sage, Thanh-An Pham, Hazen Babcock, Tomas Lukes, Thomas Pengo, Jerry Chao, Ramraj Velmurugan, Alex Herbert, Anurag Agrawal, Silvia Colabrese, Ann Wheeler, Anna Archetti, Bernd Rieger, Raimund Ober, Guy M. Hagen, Jean-Baptiste Sibarita, Jonas Ries, Ricardo Henriques, Michael Unser, Saemus Holden

Nature Methods, 2019

Preprint on Biorxiv

Single molecule challenge website hosted by EPFL

Imaging tissues and cells beyond the diffraction limit with structured illumination microscopy and Bayesian image reconstruction 

Jakub Pospíšil, Tomáš Lukeš, Justin Bendesky, Karel Fliegel, Kathrin Spendier, Guy M Hagen 

GigaScience, 2019

All of the Raw and analyzed data is freely available on the Giga-Database!

Preprint on Biorxiv

Quantitative super-resolution single molecule microscopy of YFP-tagged growth factor receptors

Tomáš Lukeš, Jakub Pospíšil, Karel Fliegel, Theo Lasser, Guy M Hagen 

GigaScience, 2018

All of the Raw and analyzed data is freely available on the Giga-Database!

Preprint on Biorxiv

PALM/STORM microscopy with a dual objective microscope 

Zdeněk Švindrych, Martin Ovesný, Guy M. Hagen 

Microscopy and imaging science: practical approaches to applied research and education, 2017

https://www.researchgate.net/publication/313513036_PALMSTORM_microscopy_with_a_dual_objective_microscope

Image analysis for single-molecule localization microscopy

Imaging of Biological Cells Using Luminescent Silver Nanoparticles

Vira Kravets, Zamavang Almemar, Ke Jiang, Kyle Culhane, Rosa Machado, Guy M. Hagen, Andriy Kotko, Igor Dmytruk, Kathrin Spendier, Anatoliy Pinchuk

Nano Research Letters, 2016

SIMToolbox: a MATLAB toolbox for structured illumination fluorescence microscopy

Pavel Křížek, Tomáš Lukeš, Martin Ovesný, Karel Fliegel, Guy M. Hagen 

Bioinformatics, 2016

SimToolbox homepage with open-source code

Test files

SIMToolbox notes

ThunderSTORM: a comprehensive ImageJ plug-in for PALM and STORM data analysis and super-resolution imaging

ThunderSTORM presentation on YouTube

SMLMS conference at EPFL, Switzerland, 2016

https://smlms.epfl.ch/

A benchmark for comparison of cell tracking algorithms

Martin Maška, Vladimír Ulman, David Svoboda, Pavel Matula, Petr Matula, Cristina Ederra, Ainhoa Urbiola, Tomás España, Subramanian Venkatesan, Deepak M.W. Balak, Pavel Karas, Tereza Bolcková, Markéta Štreitová, Craig Carthel, Stefano Coraluppi, Nathalie Harder, Karl Rohr, Klas E. G. Magnusson, Joakim Jaldén, Helen M. Blau, Oleh Dzyubachyk, Pavel Křížek, Guy M. Hagen, David Pastor-Escuredo, Daniel Jimenez-Carretero, Maria J. Ledesma-Carbayo, Arrate Muñoz-Barrutia, Erik Meijering, Michal Kozubek, Carlos Ortiz-de-Solorzano

Bioinformatics, 2014

Three-dimensional super-resolution structured illumination microscopy with maximum a posteriori probability image estimation 

Tomáš Lukeš, Pavel Křížek, Zdeněk Švindrych, Jakub Benda, Martin Ovesný, Karel Fliegel, Miloš Klíma, Guy M. Hagen 

Optics Express, 2014

High density 3D localization microscopy using sparse support recovery 

Martin Ovesný, Pavel Křížek, Zdeněk Švindrych, Guy M. Hagen 

Optics Express, 2014

3DenseSTORM homepage on Github

Imaging of insulin receptors in the plasma membrane of cells using super-resolution single molecule localization microscopy 

Pavel Křížek, Peter W. Winter, Zdeněk Švindrych, Josef Borkovec, Martin Ovesný, Deborah A. Roess, B. George Barisas, Guy M. Hagen

Microscopy: advances in scientific research and education, 2014

Separation of replication and transcription domains in nucleoli

E Smirnov, J Borkovec, L Kováčik, S Svidenska, A Schröfel, M Skalnikova, Z Švindrych, P Křížek, M Ovesný, G M Hagen, P Juda, K Michalová, MC Cardoso, D Cmarko, I Raška 

Journal of Structural Biology, 2014

Comparison of image reconstruction methods for structured illumination microscopy 

Tomáš Lukeš, Guy M. Hagen, Pavel Křížek, Zdeněk Švindrych, Karel Fliegel, Miloš Klíma 

SPIE 2014

Flexible structured illumination microscope with a programmable illumination array 

Pavel Křížek, Ivan Raška, Guy M. Hagen 

Optics Express, 2012

Minimizing detection errors in single molecule localization microscopy 

Pavel Křížek, Ivan Raška, Guy M. Hagen

Optics Express, 2011

Spatial light modulators in fluorescence microscopy 

Specific Visualization of Glioma Cells in Living Low-Grade Tumor Tissue

Sven R. Kantelhardt, Wouter Caarls, Anthony H. B. de Vries, Guy M. Hagen, Thomas M. Jovin, Walter Schulz-Schaeffer, Veit Rohde, Alf Giese, Donna J. Arndt-Jovin

PLOS ONE, 2010

Fluorescence recovery after photobleaching and photoconversion in multiple arbitrary regions of interest using a programmable array microscope

Guy M Hagen, Wouter Caarls, Keith A Lidke, Anthony HB De Vries, Cornelia Fritsch, B George Barisas, Donna J Arndt‐Jovin, Thomas M Jovin 

Microscopy Research and Technique, 2009

Dynamics of Membrane Receptors: Single‐molecule Tracking of Quantum Dot Liganded Epidermal Growth Factor

Guy M Hagen, Keith A Lidke, Bernd Rieger, Diane S Lidke, Wouter Caarls, Donna J Arndt‐Jovin, Thomas M Jovin 

Single Molecule Dynamics in Life Science, 2009

Biological applications of an LCoS-based programmable array microscope (PAM) 

Guy M. Hagen, Wouter Caarls, MartinThomas, Andrew Hill, Keith A. Lidke, Bernd Rieger, Cornelia Fritsch, Bert van Geest, Thomas M Jovin and Donna J. Arndt-Jovin 

SPIE, 2007

Spectroscopic modulation of multifunctionalized quantum dots for use as biological probes and effectors 

Sandra Miskoski, Luciana Giordano, Maria H. Etchehon, Guillermo Menendez, Keith A. Lidke, 

Guy M. Hagen, Thomas M. Jovin, Elizabeth A. Jares-Erijman

SPIE 2006

Compartmentalization of the Type I Fcε receptor and MAFA on mast cell membranes

B George Barisas, Steven M Smith, Jingjing Liu, Jinming Song, Guy M Hagen, Israel Pecht, Deborah A Roess 

Biophysical Chemistry , 2007

Fluorescence photobleaching recovery using total internal reflection interference fringes

Guy M. Hagen, Deborah A. Roess, B. George Barisas

Analytical Biochemistry, 2006


Luteinizing Hormone Receptors Translocate to Plasma Membrane Microdomains after Binding of Human Chorionic Gonadotropin

Steven ML Smith, Ying Lei, Jingjing Liu, Mary E Cahill, Guy M Hagen, B George Barisas, Deborah A Roess

Endocrinology, 2006

High Probe Intensity Photobleaching Measurement of Lateral Diffusion in Cell Membranes 

Guy M Hagen, Deborah A. Roess, Gildardo Cruz de León , B. George Barisas

Journal of Fluorescence, 2005

Flexible normally on photomultiplier gating strategy for reducing postgate artifacts 

Guy M Hagen, Guangzhong Gao, Deborah A Roess, B George Barisas 

Review of Scientific Instruments, 2005

Lateral diffusion measurements on genetically introduced fluorescent proteins

B George Barisas, Deborah A Roess, Gildardo Cruz de Leon, Guy M Hagen 

SPIE, 2004

The Mast Cell Function-Associated Antigen and Its Interactions with the Type I Fcε Receptor

Jinming Song, Guy M. Hagen, Deborah A. Roess, Israel Pecht, B. George Barisas

Biochemistry, 2002