Theme 1: Using Open Source Platform iCn3D, develop new universal modules for molecular interactions analysis
Differential analysis of viral protein sequence-variants interactions with host proteins
1D/2D/3D MAPS of Viral Surface Protein Domains and Interactions (Intermolecular vs intramolecular)
Integration of externally computed DATA (atom/residue based properties) for visualization on structure and data analysis in a structural context
Adding protein-ligand interactions descriptors useful for structure-based drug discovery
Theme 2: Development of (prototype) Algorithms/Tools/Databases for protein structure and interaction analysis
Creation of a prototype SARS-CoV-2 Virus Mutation Database
Impact of viral protein sequence variants on protein domains and interfaces: Tool to evaluate impact of a mutation
Symmetry, Structural Analysis and Model building
Creation of a Membrane Protein Extended Topology Standard for Surface Proteins
Theme 3: Usability - User Interface, Automation, etc.
Windowing, Data management, Project management, Cloud etc.
Reference sequence numbering and mapping