Paul Gugger

Ecological Genomics

Paul Gugger headshot

Paul F. Gugger

Research Scholar, Ronin Institute

Adjunct Faculty, University of Maryland Center for Environmental Science

Senior Scientist, NYU Langone Health

Ph.D., University of Minnesota, 2010

B.S., Duke University, 2003

CV | Resume

Research Interests

My research focuses on how populations of long-lived trees respond evolutionarily to environmental variation and what are the implications for conservation under global change. I address these questions in trees of ecological and economic importance and have primarily approached them in two ways. 1) I have studied past demographic responses to large-scale climate change such as glacial cycles, integrating phylogeography, paleoecology, and climate niche models. 2) I investigate the capacity for short-term adaptive evolutionary change through three mechanisms: selection on standing (existing) genetic variation within and among populations, novel genetic variation that enters a species through hybridization, and epigenetic mechanisms such as DNA methylation. For these, I develop and apply ‘omic tools in modern populations, typically at landscape scales, and use models to predict population resilience and vulnerability to environmental change. My research plans emphasize large-scale genomic approaches that bring my two lines of research together to understand adaptive evolutionary responses to environmental change over different temporal and spatial scales.

I am also more broadly interested in the analysis of genomic and other ‘omics data. I collaborate on diverse projects, such as population and comparative genomics of plants, conservation genomics in bats, and metabarcoding in metazoans and microbes. In my "day job" at NYU Langone Health, I analyze single-cell RNA-Seq and ATAC-Seq data as part of a diabetes research group.

I am always open to new collaborations. Please contact me if interested.