My research focuses on how tumor microenvironmental factors, especially hypoxia, modulate tumor progression and treatment outcomes through a continuum mathematical modeling framework.

Peer-Reviewed Articles

• Gopinath Sadhu and D.C. Dalal (2024). A mathematical study of the interaction between oxygen and lactate in an in vitro and in vivo tumor. Int. J. Biomath. 

• Gopinath Sadhu and D.C. Dalal (2025). Effects of non-linear interaction between oxygen and lactate on solid tumor growth under cyclic hypoxia. Bull. Math. Biol.

•  Gopinath Sadhu (2026). A mathematical investigation of exosome and lactate levels interplay in an in vitro and in vivo tumors. Bull. Math. Biol.

• Gopinath Sadhu, Helen M. Byrne and D.C. Dalal (2026). The impact of oxygen heterogeneity on epithelial-to-mesenchymal transitions: a numerical study. J. Math. Biol. 

• Gopinath Sadhu, Paras Jain, Jason T George and Mohit Kumar Jolly (2026). A phenotype-structured PDE framework for investigating the role of hypoxic memory on tumor invasion under cyclic hypoxia. Bull. Math. Biol. (Accepted)

• K S Yadav and Gopinath Sadhu (2025). Effect of inosine on recurrence of tumor after radiation therapy: A mathematical investigation. J. Theor. Biol. 

• Rupchand Sutradhar, Gopinath Sadhu and D.C. Dalal (2026). Multi-point Infection Dynamics of Hepatitis B in the Presence of Sub-Viral Particles. Bull. Math. Biol. 

Please visit my Google scholar page and Research gate page