8:00 - 8:10 am
8:10-8:20 am
8:20-8:25 am
Karin Hoffmeister, MD, Director of Translational Glycomics Center
Chris Miskel, Versiti, BloodCenter of Wisconsin
Gilbert C. White, II, MD, Blood Research Institute, BloodCenter of Wisconsin, Versiti
Session Chairs: M. Lee-Sundlov, PhD; L. Rivadeneyra, PhD
8:25 - 9:15 am
9:15 - 9:30 am
9:30 - 9:45 am
Keynote Lecture: Glycomimetic Drugs that Target the Tumor Microenvironment in Clinical Trials for Hematological Malignancies
John Magnani, PhD, GlycoMimetics, Inc.
Red Blood Cell Glycomics: Past, Present, and Future
Waseem Anani, MD, Associate Medical Director of Transfusion Medicine and Assistant Clinical Professor of Pathology
Aberrant Sialylation and the Pathobiology of Thrombocytopenia
Melissa Lee-Sundlov, PhD, Blood Research Institute, BloodCenter of Wisconsin
9:45 - 10:00 am
Coffee Break
Session Chair: S. Haberichter, PhD ; S. Giannini, PhD
10:00-10:30 am
10:30-11:00 am
11:00-11:15 am
11:15-11:30 am
11:30-11:45 am
11:45- 11:50 am
Glycans in the Bone Marrow Niche
Silvia Giannini, PhD, Brigham and Women’s Hospital
Invited Speaker: Platelets Regulate a Novel Mode of Extracellular Glycosylation
Joseph T.Y. Lau, PhD, Roswell Park Comprehensive Cancer Center
Absence of β-1,4-Galactosyltransferase Severely Affects the Bone Marrow Niche
Leonardo Rivadeneyra, PhD, Blood Research Institute, BloodCenter of Wisconsin
Integrin Function and Glycans
Jieqing Zhu, PhD, Blood Research Institute
Development of an Assay to Determine von Willebrand Factor Glycan Composition
Connie Kwas, MS, Blood Research Institute, BloodCenter of Wisconsin
Poster Presentation
Alicia Eustes, University of Utah
BRI - Cafeteria
Session Chairs: M. Burke, MD; N. Dahms, PhD
1:00-1:30 pm
1:30-1:45 pm
1:45-2:00 pm
2:00-2:15 pm
2:15-2:30 pm
2:30-2:45 pm
Treatment Strategies for Globoid Cell Leukodystrophy: Successes and Challenges
Mark Sands, PhD, Washington University School of Medicine in St. Louis
Glycan Changes in Dorsal Root Ganglia are Associated with Fabry Disease Pain
Jimmy Miller, PhD, Medical College of Wisconsin
T Rapa Cells as Delivery Vehicles for α-galactosidase A in Fabry Patients
Murtaza Nagree, Medical College of Wisconsin
Linking Glycans and Reduced Von Willebrand Factor Survival
Sandra Haberichter, PhD, Blood Research Institute, BloodCenter of Wiscosin
ATB200: A Novel rhGAA ERT with Optimized Glycosylation for Improved Therapeutic Efficacy
Russell Gotschall, Amicus Therapeutics
M6PR-specific Targeting of Lysosomal Enzymes Regulates Platelet Production and Function in Mice
Hervé Falet, PhD, Blood Research Institute, BloodCenter of Wisconsin
2:45 - 3:00 pm
Coffee Break
Session Chair: R. Gundry, PhD; W. Anani, PhD
3:00-3:30 pm
3:30-3:45 pm
3:45-4:05 pm
Glycosaminoglycan Specificity – A Pipe Dream?
Umesh Desai, PhD, Virginia Commonwealth University
Glycosaminoglycan Modulation of Chemokine Function
Brian Volkman, PhD, Medical College of Wisconsin
Invited Speaker: Mapping the Cardiomyocyte Surfaceome: New Technologies for Studying Glycoproteins in Differentiation and Disease
Rebekah Gundry, PhD, Medical College of Wisconsin
4:05-4:10 pm
Karin Hoffmeister, MD, Blood Research Institute, BloodCenter of Wisconsin
4:15-7:00 pm
Joint session with the Mass Spectrometry Research Symposium in the Medical College of Wisconsin – Alumni Center