For my PhD, I started a research system to study western fence lizards (Sceloporus occidentalis) in the Great Basin Desert of Northern Nevada. For 3 years, I have been tracking two populations of these lizards, living in drastically different thermal environments, alongside fellow graduate students, postdoctoral researchers, and a small team of undergraduates, through mark-recapture. To date, we have uniquely identified over 900 individuals and recorded more than 3,500 captures. I combine this immense database with lab-based measurements and high-resolution thermal landscapes to understand how macro- and microclimatic differences shape natural selection on traits such as metabolic rates and gestation length.