Download GetData Graph Digitizer 2.26.0.20 from our website for free. GetData Graph Digitizer can be installed on Windows 2000/XP/Vista/7/8/10/11 environment, 32-bit version. The most frequent installer filenames for the software include: GetDataW.exe and GetData.exe etc. Our built-in antivirus scanned this download and rated it as 100% safe. The program belongs to Office Tools. The most popular version of the program is 2.2. This program was originally produced by getdata-graph-digitizer.
A systematic literature search was conducted March 2017 to identify data on efficacy and safety outcomes of treatments for frontline CLL. PFS and OS Kaplan-Meier curves were manually digitised using GetData Graph Digitizer (version 2.26). Potential treatment modifying variables were also extracted. Seventeen publications included data for PFS at 24 months (PFS24) and OS at 36 (OS36) and 60 months (OS60). Each treatment arm of each trial was considered as an independent observation. Pearson's correlation was used to calculate the correlation between OS36 or OS60, and treatment modifying variables and PFS24. Significantly correlated variables were then utilised in the robust ordinary least squares (OLS) regression analyses to develop models that could predict OS from PFS. Using the same data, a second analysis was performed with Cox semi-parametric models. First patient-level OS and PFS data were recreated using the Guyot algorithm. Next, to inform the modelling strategy, the validity of proportional hazards (PH) assumptions were checked using three methods: log log plot graphical observation, Cox model check, and Schoenfeld's residuals from the Cox model. Hazard ratios (HRs) were then derived from the models.
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