Publications

Georgios D. Koutsovoulos, Eder Marques, Marie-Jeanne Arguel, Laurent Duret, Andressa C.Z. Machado, Regina M.D.G. Carneiro, Djampa K. Kozlowski, Marc Bailly-Bechet, Philippe Castagnone-Sereno, Erika V.S. Albuquerque, and Etienne G.J. Danchin. Population genomics supports clonal reproduction and multiple independent gains and losses of parasitic abilities in the most devastating nematode pest. Evolutionary Applications, 2019

Erik J. Ragsdale, Georgios Koutsovoulos, and Joseph F. Biddle. A draft genome for a species of Halicephalobus (Panagrolaimidae). Journal of Nematology, 2019

Philippe Castagnone-Sereno, Karine Mulet, Etienne G. J. Danchin, Georgios D. Koutsovoulos, Mgane Karaulic, Martine Da Rocha, Marc Bailly-Bechet, Loris Pratx, Laetitia Perfus-Barbeoch, and Pierre Abad. Gene copy number variations as signatures of adaptive evolution in the parthenogenetic, plant-parasitic nematode Meloidogyne incognita. Molecular Ecology, 2019

Franklin Wang-Ngai Chow*, Georgios Koutsovoulos*, Cesaré Ovando-Vázquez*, Kyriaki Neophytou, Jose R Bermúdez-Barrientos, Dominik R Laetsch, Elaine Robertson, Sujai Kumar, Julie M Claycomb, Mark Blaxter, Cei Abreu-Goodger, and Amy H Buck. Secretion of an Argonaute protein by a parasitic nematode and the evolution of its siRNA guides. Nucleic Acids Research, 2019

Sophie Tandonnet, Georgios D. Koutsovoulos, Sally Adams, Delphine Cloarec, Manish Parihar, Mark L. Blaxter, and Andre Pires-daSilva. Chromosome-wide evolution and sex determination in the three-sexed nematode Auanema rhodensis. G3: Genes, Genomes, Genetics, 2019

International Helminth Genomes Consortium. Comparative genomics of the major parasitic worms. Nature Genetics, 2018

E. Yilmaz, S. Wongkamchai, S. Ramnke, G. D. Koutsovoulos, M. L. Blaxter, S. Poppert, R. Schaper, G. von Samson-Himmelstjerna, and J. Krcken. High genetic diversity in the Dirofilaria repens species complex revealed by mitochondrial genomes of feline microfilaria samples from Narathiwat, Thailand. Transboundary and Emerging Diseases, 2018

Philipp H. Schiffer, Avital L. Polsky, Alison G. Cole, Julia I. R. Camps, Michael Kroiher, David H. Silver, Vladislav Grishkevich, Leon Anavy, Georgios Koutsovoulos, Tamar Hashimshony, and Itai Yanai. The gene regulatory program of Acrobeloides nanus reveals conservation of phylum-specific expression. Proceedings of the National Academy of Sciences, 2018

Mark McMullan, Maryam Rafiqi, Gemy Kaithakottil, Bernardo J. Clavijo, Lorelei Bilham, Elizabeth Orton, Lawrence Percival-Alwyn, Ben J. Ward, Anne Edwards, Diane G. O. Saunders, Gonzalo Garcia Accinelli, Jonathan Wright, Walter Verweij, Georgios Koutsovoulos, Kentaro Yoshida, Tsuyoshi Hosoya, Louisa Williamson, Philip Jennings, Renaud Ioos, Claude Husson, Ari M. Hietala, Adam Vivian-Smith, Halvor Solheim, Dan MaClean, Christine Fosker, Neil Hall, James K. M. Brown, David Swarbreck, Mark Blaxter, J. Allan Downie, and Matthew D. Clark. The ash dieback invasion of Europe was founded by two genetically divergent individuals. Nature Ecology & Evolution, 2018

Sophie Tandonnet, Maureen C. Farrell, Georgios D. Koutsovoulos, Mark L. Blaxter, Manish Parihar, Penny L. Sadler, Diane C. Shakes, and Andre Pires-daSilva. Sex- and gamete-specific patterns of X chromosome segregation in a trioecious nematode. Current Biology, 2018

Marc Harper, Vincent Knight, Martin Jones, Georgios Koutsovoulos, Nikoleta E. Glynatsi, and Owen Campbell. Reinforcement learning produces dominant strategies for the iterated prisoner’s dilemma. PLOS ONE, 2017

Fabrice Besnard*, Georgios Koutsovoulos*, Sana Dieudonné, Mark Blaxter, and Marie-Anne Félix. Toward universal forward genetics: Using a draft genome sequence of the nematode Oscheius tipulae to identify mutations affecting vulva development. Genetics, 2017

Yuki Yoshida*, Georgios Koutsovoulos*, Dominik R. Laetsch, Lewis Stevens, Sujai Kumar, Daiki D. Horikawa, Kyoko Ishino, Shiori Komine, Takekazu Kunieda, Masaru Tomita, Mark Blaxter, and Kazuharu Arakawa. Comparative genomics of the tardigrades Hypsibius dujardini and Ramazzottius varieornatus. PLOS Biology, 2017

Sebastian Eves-van den Akker, Dominik R. Laetsch, Peter Thorpe, Catherine J. Lilley, Etienne G. J. Danchin, Martine Da Rocha, Corinne Rancurel, Nancy E. Holroyd, James A. Cotton, Amir Szitenberg, Eric Grenier, Josselin Montarry, Benjamin Mimee, Marc-Olivier Duceppe, Ian Boyes, Jessica M. C. Marvin, Laura M. Jones, Hazijah B. Yusup, Joël Lafond-Lapalme, Magali Esquibet, Michael Sabeh, Michael Rott, Hein Overmars, Anna Finkers-Tomczak, Geert Smant, Georgios Koutsovoulos, Vivian Blok, Sophie Mantelin, Peter J. A. Cock, Wendy Phillips, Bernard Henrissat, Peter E. Urwin, Mark Blaxter, and John T. Jones. The genome of the yellow potato cyst nematode, Globodera rostochiensis, reveals insights into the basis of parasitism and virulence. Genome Biology, 2016

Vincent Knight, Owen Campbell, Marc Harper, Karol M. Langner, James Campbell, Thomas Campbell, Alex Carney, Martin Chorley, Cameron Davidson-Pilon, Kristian Glass, Nikoleta Glynatsi, Tomáš Ehrlich, Martin Jones, Georgios Koutsovoulos, Holly Tibble, Jochen Muller, Geraint Palmer, Piotr Petunov, Paul Slavin, Timothy Standen, Luis Visintini, and Karl Molden. An open framework for the reproducible study of the iterated prisoner’s dilemma. Journal of Open Research Software, 2016

Georgios Koutsovoulos, Sujai Kumar, Dominik R. Laetsch, Lewis Stevens, Jennifer Daub, Claire Conlon, Habib Maroon, Fran Thomas, Aziz A. Aboobaker, and Mark Blaxter. No evidence for extensive horizontal gene transfer in the genome of the tardigrade Hypsibius dujardini. Proceedings of the National Academy of Sciences, 2016

Angus Davison, Gary S. McDowell, Jennifer M. Holden, Harriet F. Johnson, Georgios D. Koutsovoulos, M.Maureen Liu, Paco Hulpiau, Frans VanRoy, Christopher M. Wade, Ruby Banerjee, Fengtang Yang, Satoshi Chiba, John W. Davey, Daniel J. Jackson, Michael Levin, and Mark L. Blaxter. Formin is associated with left-right asymmetry in the pond snail and the frog. Current Biology, 2016

Judith Risse, Marian Thomson, Sheila Patrick, Garry Blakely, Georgios Koutsovoulos, Mark Blaxter, and Mick Watson. A single chromosome assembly of Bacteroides fragilis strain BE1 from Illumina and MinION nanopore sequencing data. GigaScience, 2015

Peter Sarkies, Murray E. Selkirk, John T. Jones, Vivian Blok, Thomas Boothby, Bob Goldstein, Ben Hanelt, Alex Ardila- Garcia, Naomi M. Fast, Phillip M. Schiffer, Christopher Kraus, Mark J. Taylor, Georgios Koutsovoulos, Mark L. Blaxter, and Eric A. Miska. Ancient and novel small RNA pathways compensate for the loss of piRNAs in multiple independent nematode lineages. PLOS Biology, 2015

Mark Blaxter and Georgios Koutsovoulos. The evolution of parasitism in Nematoda. Parasitology, 2015

Amir Szitenberg, Georgios Koutsovoulos, Mark L. Blaxter, and David H. Lunt. The evolution of tyrosine-recombinase elements in Nematoda. PLOS ONE, 2014

Georgios Koutsovoulos, Benjamin Makepeace, Vincent N. Tanya, and Mark Blaxter. Palaeosymbiosis revealed by genomic fossils of Wolbachia in a strongyloidean nematode. PLOS Genetics, 2014

David H. Lunt, Sujai Kumar, Georgios Koutsovoulos, and Mark L. Blaxter. The complex hybrid origins of the root knot nematodes revealed through comparative genomics. PeerJ, 2014

Philipp H. Schiffer, Michael Kroiher, Christopher Kraus, Georgios D. Koutsovoulos, Sujai Kumar, Julia I. R Camps, Ndifon A. Nsah, Dominik Stappert, Krystalynne Morris, Peter Heger, Janine Altmüller, Peter Frommolt, Peter Nürnberg, W. Kelley Thomas, Mark L. Blaxter, and Einhard Schierenberg. The genome of Romanomermis culicivorax : revealing fundamental changes in the core developmental genetic toolkit in Nematoda. BMC Genomics, 2013

Sujai Kumar, Martin Jones, Georgios Koutsovoulos, Michael Clarke, and Mark Blaxter. Blobology: exploring raw genome data for contaminants, symbionts and parasites using taxon-annotated GC-coverage plots. Frontiers in Genetics, 2013

Francesco Comandatore, Davide Sassera, Matteo Montagna, Sujai Kumar, Georgios Koutsovoulos, Graham Thomas, Charlotte Repton, Simon A. Babayan, Nick Gray, Richard Cordaux, Alistair Darby, Benjamin Makepeace, and Mark Blaxter. Phylogenomics and analysis of shared genes suggest a single transition to mutualism in Wolbachia of nematodes. Genome Biology and Evolution, 2013

Jianbin Wang, Makedonka Mitreva, Matthew Berriman, Alicia Thorne, Vincent Magrini, Georgios Koutsovoulos, Sujai Kumar, Mark L. Blaxter, and Richard E. Davis. Silencing of germline-expressed genes by DNA elimination in somatic cells. Developmental Cell, 2012

Christelle Godel, Sujai Kumar, Georgios Koutsovoulos, Philipp Ludin, Daniel Nilsson, Francesco Comandatore, Nicola Wrobel, Marian Thompson, Christoph D. Schmid, Susumu Goto, Frédéric Bringaud, Adrian Wolstenholme, Claudio Bandi, Christian Epe, Ronald Kaminsky, Mark Blaxter, and Pascal Mäser. The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets. The FASEB Journal, 2012

Mark Blaxter, Sujai Kumar, Gangajot Kaur, Georgios Koutsovoulos, and Ben Elsworth. Genomics and transcriptomics across the diversity of the Nematoda. Parasite Immunology, 2012

Sujai Kumar, Georgios Koutsovoulos, Gaganjot Kaur, and Mark Blaxter. Toward 959 nematode genomes. Worm, 2012

Martin O. Jones, Georgios D. Koutsovoulos, and Mark L. Blaxter. iPhy: an integrated phylogenetic workbench for supermatrix analyses. BMC Bioinformatics, 2011