Our research at GenBioD, integrates genomics, synthetic biology, and biological engineering to discover novel microorganisms, decode their genomes, and engineer living systems for sustainable applications.
Guided by the read–write–edit genomes, we aim to read nature’s blueprints through next-generation sequencing, write new biological functions using synthetic biology, and edit genomes to build optimized microbial systems for the future of bio-based innovation.
We isolate and study microorganisms from diverse and extreme environments — from marine habitats to soil ecosystems. These unexplored microbes often harbor unique metabolic pathways and enzymes with remarkable biotechnological potential.
By characterizing these organisms and their enzymes, we aim to uncover new biocatalysts and biomolecules for industrial and environmental applications.
Using next-generation sequencing (NGS) and advanced bioinformatics, we explore the genomes of newly isolated microorganisms to reveal their metabolic potential, genetic novelty, and evolutionary relationships.
Through comparative and functional genomics, we identify key genes, operons, and pathways that can be harnessed for bioprocesses, biosynthesis, and environmental resilience.
Applying the principles of synthetic biology, we redesign microbial systems to perform new or enhanced functions. This includes metabolic engineering, genome editing, and pathway reconstruction to enable sustainable production of value-added chemicals, biofuels, and biomaterials.
Design–build–test–learn (DBTL) approach of synthetic biology allows us to transform genomic insights into practical, engineered solutions.
We employ metagenomics and environmental DNA (eDNA) tracing to profile microbial diversity and functional potential across diverse environments. By analyzing microbial community structures and their genetic signatures, we gain insights into ecosystem health, biogeochemical processes, and species interactions.
Our eDNA-based metabarcoding approaches are applied in ecological assessment, disease surveillance, and food quality monitoring, while also extending to areas such as environmental forensics, biosecurity, and tracking invasive or endangered species. Through these studies, we aim to develop reliable molecular tools for real-time monitoring of biological systems and environmental change.