Geetanjali Singh

My research focuses on the de novo synthesis of antimicrobial peptides (AMPs), peptide-based molecules and small molecule-peptide conjugate to combat the prevalent multi drug resistance (MDR) phenomenon and as an improvement or alternative to the existing antibiotics. My research aims to establish the fundamental biotechnology principles for developing a new class of peptide antimicrobials by using innovative strategies, aiming to establish principles of a priori design of AMPs by a combination of empirical methods and machine learning-driven drug discovery to explore means of improving pharmacokinetic properties of AMPs by the use of co-crystallization, derivatization with unnatural and natural amino acids and enclosure by nanostructured delivery matrices.