Publications

2024

• Ju-El Kim, Gun-Jae Jeong, Young Min Yoo, Suk Ho Bhang, Jae Hoon Kim, Young Min Shin, Kyung Hyun Yoo, Byung-Chul Lee, Wooyeol Baek, Dong Nyoung Heo, Rosaire Mongrain, Jung Bok Lee and Jeong-Kee Yoon. 3D bioprinting technology for modeling vascular diseases and its application. Biofabrication. 2025 Mar; (Accepted Manuscript) 

• Oh SJ, Shin YY, Ahn JS, Park HJ, Kang MJ, Shin TH, Lee BC, Kim WK, Oh JM, Lee D, Kim YH, Kim JM, Sung ES, Lee EW, Jeong JH, Lee BJ, Seo Y, Kim HS. TGFβ2-Driven Ferritin Degradation and Subsequent Ferroptosis Underlie Salivary Gland Dysfunction in Postmenopausal Conditions. Adv Sci (Weinh). 2024 Dec;11(47).

•  Lee BC. Challenges and innovations in hematopoietic stem cell transplantation: Exploring bone marrow niches and new model systems. BMB Reports. 2024 Aug;57(8):352-362.

• Shin D, Kim MJ, Chun S, Kim D, Lee C, Ahn KS, Jung E, Kim D, Lee BC, Hwang D, Kim Y, Yoon SS. Elucidation of molecular basis of osteolytic bone lesions in advanced multiple myeloma. Haematologica. 2024 Jul 1;109(7):2207-2218.

• Park HS*, Lee BC*, Chae DH, Yu A, Park JH, Heo J, Han MH, Cho K, Lee JW, Jung JW, Dunbar CE, Oh MK, Yu KR. Cigarette smoke impairs the hematopoietic supportive property of mesenchymal stem cells via the production of reactive oxygen species and NLRP3 activation. Stem Cell Res Ther. 2024 May 20;15(1):145.

• Lee BC*, Gin A*, Wu C, Singh S, Grice M, Mortlock R, Abraham A, Fan X, Zhou Y, Aljanahi A, Choi U, deRavin SS, Shin TH, Hong S, Dunbar CE. Impact of CRISPR/HDR-editing versus lentiviral transduction on long-term engraftment and clonal dynamics of HSPCs in rhesus macaques. Cell Stem Cell. 2024 Apr 4;31(4):455-466. (Correspondence)

2023

•  Shin TH, Zhou Y, Lee BC, Hong SG, Andrew SF, Flynn BJ, Gagne M, Todd JM, Moore IN, Cook A, Lewis MG, Foulds KE, Seder RA, Douek DC, Roederer M, Dunbar CE. Investigation of the impact of clonal hematopoiesis on severity and pathophysiology of COVID-19 in rhesus macaques. Front Vet Sci. 2023 Jul 6;10:1152197.

•   Lee BC*, Zhou Y*, Bresciani E, Ozkaya N, Dulau-Florea A, Carrington B, Shin TH, Baena V, Syed ZA, Hong SG, Zhen T, Calvo KR, Liu P, Dunbar CE. A RUNX1-FPDMM rhesus macaque model reproduces the human phenotype and predicts challenge to curative gene therapies. Blood. 2023 Jan 19;141(3):231-237.

2022

•  Ahn JS, Shin YY, Oh SJ, Song MH, Kang MJ, Park SY, Nguyen PT, Nguyen DK, Kim HK, Han J, Vasileva EA, Mishchenko NP, Fedoreyev SA, Stonik VA, Seo Y, Lee BC*, Kim HS*. Implication of Echinochrome A in the Plasticity and Damage of Intestinal Epithelium. Mar Drugs. 2022 Nov 14;20(11), 715.

•  Seo Y, Ahn JS, Shin YY, Oh SJ, Song MH, Kang MJ, Oh JM, Lee D, Kim YH, Lee BC, Shin TH, Kim HS. Mesenchymal stem cells target microglia via galectin-1 production to rescue aged mice from olfactory dysfunction. Biomed Pharmacother. 2022 Jul 2;153:113347.

• Shin TH, Zhou Y, Chen S, Cordes S, Grice MZ, Fan X, Lee BC, AlJanahi AA, Hong SG, Vaughan KL, Mattison JA, Kohama SG, Fabre MA, Uchida N, Demirci S, Corat MAF, Métais JY, Calvo KR, Buscarlet M, Natanson H, McGraw KL, List AF, Busque L, Tisdale JF, Vassiliou GS, Yu KR, Dunbar CE. A Macaque Clonal Hematopoiesis Model Demonstrates Expansion of TET2-Disrupted Clones and Utility for Testing Interventions. Blood. 2022 Oct 20;140(16):1774-1789.

2013~2021 (selected)

• Lee BC, Lozano RJ, Dunbar CE. Understanding and Overcoming Adverse Consequences of Genome Editing on Hematopoietic Stem and Progenitor Cells. Mol Ther. 2021;29(11):3205-3218.

• AlJanahi AA, Lazzarotto CR, Chen S, Shin TH, Cordes S, Fan X, Jabara I, Zhou Y, Young DJ, Lee BC, Yu KR, Li Y, Toms B, Tunc I, Hong SG, Truitt LL, Klermund J, Andrieux G, Kim MY, Cathomen T, Gill S, Tsai SQ, Dunbar CE. Prediction and Validation of Hematopoietic Stem and Progenitor Cell Off-Target Editing in Transplanted Rhesus Macaques. Mol Ther. 2021;30(1):209-222.

• Lee BC*, Lee JY*, Kim J*, Shin N, Yoo JM, Kang I, Kim JJ, Lee SE, Kim D, Choi SW, Hong BH, Kang KS. Oral administration of microbiome-friendly graphene quantum dots as therapy for colitis. 2d mater. 2021;8(2):025036.

• Kang I, Yoo JM, Kim D, Kim J, Cho MK, Lee SE, Kim DJ, Lee BC, Lee JY, Kim JJ, Shin N, Choi SW, Lee YH, Ko HS, Shin S, Hong BH, Kang KS. Graphene quantum dots alleviate impaired functions in Niemann-Pick disease type C in vivo. Nano Lett. 2021;21(5):2339-2346.

• Lee BC*, Lee JY*, Kim J, Yoo JM, Kang I, Kim JJ, Shin N, Kim DJ, Choi SW, Kim D, Hong BH, Kang KS. Graphene quantum dots as anti-inflammatory therapy for colitis. Sci Adv. 2020;6(18):eaaz2630.

• Kim JJ, Kim DH, Lee JY, Lee BC, Kang I, Kook MG, Kong D, Choi SW, Woo HM, Kim DI, Kang KS. cAMP/EPAC signaling enables ETV2 to induce endothelial cells with high angiogenesis potential. Mol Ther. 2019;S1525-0016(19)30537-4.

• Lee BC, Kim JJ, Lee JY, Kang I, Shin N, Lee SE, Choi SW, Cho JY, Kim HS, Kang KS. Disease-specific primed human adult stem cells effectively ameliorate experimental atopic dermatitis. Theranostics. 2019;9(12):3608.

• Kang I, Lee BC, Lee JY, Kim JJ, Sung EA, Lee SE, Shin N, Choi SW, Seo Y, Kim HS, Kang KS. Stem cell-secreted 14,15-epoxyeicosatrienoic acid rescues cholesterol homeostasis and autophagic flux in Niemann-Pick-type C disease. Exp Mol Med. 2018;50(11):149.

• Lee BC*, Shin N*, Lee JY, Kang I, Kim JJ, Lee SE, Choi SW, Wester GA, Kang KS. MIS416 Enhances Therapeutic Functions of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Against Experimental Colitis by Modulating Systemic Immune Milieu. Front Immunol. 2018;9:1078.

• Lee JY, Yu KR, Lee BC, Kang I, Kim JJ, Jung EJ, Kim HS, Seo Y, Choi SW, Kang KS. GATA4-dependent regulation of the secretory phenotype via MCP-1 underlies lamin A-mediated human mesenchymal stem cell aging. Exp Mol Med. 2018;50(5):63.

• Kang I*, Lee BC*, Choi SW*, Lee JY, Kim JJ, Kim BE, Kim DH, Lee SE, Shin N, Seo Y, Kim HS, Kim DI, Kang KS. Donor-dependent Variation of Human Umbilical Cord Blood Mesenchymal Stem Cells in Response to Hypoxic Preconditioning and Amelioration of Limb Ischemia. Exp Mol Med. 2018;50(4):35.

• Shin TH, Kim HS, Kang TW, Lee BC, Lee HY, Kim YJ, Shin JH, Seo Y, Won Choi S, Lee S, Shin K, Seo KW, Kang KS. Human umbilical cord blood-stem cells direct macrophage polarization and block inflammasome activation to alleviate rheumatoid arthritis. Cell Death Dis. 2016;7(12):e2524.

• Seo Y, Kim HS, Kang I, Choi SW, Shin TH, Shin JH, Lee BC, Lee JY, Kim JJ, Kook MG, Kang KS. Cathepsin S contributes to microglia-mediated olfactory dysfunction through the regulation of Cx3cl1-Cx3cr1 axis in a Niemann-Pick disease type C1 model. Glia. 2016;64(12):2291-305.

• Kim HS, Yun JW, Shin TH, Lee SH, Lee BC, Yu KR, Seo Y, Lee S, Kang TW, Choi SW, Seo KW, Kang KS. Human umbilical cord blood mesenchymal stem cell-derived PGE2 and TGF-beta1 alleviate atopic dermatitis by reducing mast cell degranulation. Stem Cells. 2015;33(4):1254-66.

• Kim HS, Shin TH, Lee BC, Yu KR, Seo Y, Lee S, Seo MS, Hong IS, Choi SW, Seo KW, Nunez G, Park JH, Kang KS. Human umbilical cord blood mesenchymal stem cells reduce colitis in mice by activating NOD2 signaling to COX2. Gastroenterology. 2013;145(6):1392-403 e1-8.

Link to Complete List of Publications