My research work involves developing a renal fibrosis model that resembles the in vivo conditions using an extrusion-based bioprinting technique that allows precise patterning of cells combined with tissue-specific decellularized ECM (dECM) and by coculturing multiple cells together. The bioprinted construct is further matured in a tissue miniature customized bioreactor (TMCB) with in vivo flow rates. The use of tissue-specific dECM as a bioink for 3D bioprinting allows proper cell-cell & cell - ECM contacts that are crucial for any basic biological mechanisms. Additionally, the 3D bioprinting technique employed in this study allows the spatial arrangement of various cells in specific locations and permits three-dimensional cellular organization and tissue-specific physiological conditions. Hence, the developed in vitro model help in understanding disease progression and developing novel therapeutic methods, and drug toxicity studies.

I also have previous experience working as a Senior research fellow for 2.5 years at the Center for Cellular & Molecular Biology (CCMB). My role involved laboratory testing of samples sourced from various institutions to interpret the structural characteristics using different biophysical techniques. I carried out multiple research activities on the anti-cancer property of synthetic molecules and their binding interactions with DNA using cell culture assays and spectroscopic techniques. I have knowledge of working with innovation and incubation start-ups at Atal Incubation Center (AIC), CCMB, in addressing different roadblocks start-ups face, such as identifying the size of the particles and analyzing the secondary structure of proteins.

I am equipped with strong fundamentals in science from the University of Hyderabad, and from the teaching experience at Aurora Degree College (ADC) where I built an ability to communicate the subjects effectively.