Toshinori Fujie Research Group

Laboratory for Integrated NanoBioElectronics

Nexus of Nano, Bio and Electronics for Human Healthcare

Welcome to Fujie Lab @ Tokyo Institute of Technology! 

We are envisaging the development of innovative therapeutics and diagnostics.






News 2023


New paper is out! 

Kon investigated the effect of oligoethylene glycol-based self-assembled monolayers on electrochemical aptamer-based sensor. This work has been achieved under the collaboration with Prof. Kevin Plaxco in UCSB and Dr. Takanori Uzawa in RIKEN.

Son, K., Uzawa, T., Ito, Y., Kippin, T., Plaxco, K. W.*, Fujie, T*(Corresponding). Survey of oligoethylene glycol-based self-assembled monolayers on electrochemical aptamer-based sensor in biological fluids. Biochem. Biophys. Res. Commun., 668, 1-7 (2023). (DOI: 10.1016/j.bbrc.2023.05.032)


Award Announcement

Tatsuhiro received the FSE Best Poster Award in The 5th Event of the Young Researchers Society for Flexible and Stretchable Electronics! Congratulations!!

Conference Information

2023.6.21, 日本接着学会 若手交流シンポジウム2023

[1] 藤枝 俊宣.「エレクトロニクスの薄膜化により創発される医療・ヘルスケア技術」日本接着学会 若手交流シンポジウム2023 (2023.6.21, 東京). 

[2] 山田 佑, 水野 陽介, 藤枝 俊宣.「3Dバイオプリンティングに向けたカルボキシメチルキトサンとタンニン酸からなる自己修復性ハイドロゲルの作製」日本接着学会 若手交流シンポジウム2023 (2023.6.21, 東京).

[3] 関田 大生, 水野 陽介, 藤田 創, 藤枝 俊宣.「ピロガロール基を有するエラストマー薄膜の作製と接着性評価」日本接着学会 若手交流シンポジウム2023 (2023.6.21, 東京).

2023.6.5-8 Biosensors 2023

[1] Son, K., Uzawa, T., Ito, Y., Kippin, T., Plaxco, K. W., Fujie, T. Real-time monitoring of brain dopamine levels using electrochemical aptamer-based (E-AB) sensors. Biosensors 2023 (2023.6.5., Busan).

2023.5.24-26, 第72回高分子年次大会

[1] 山田 佑, 水野 陽介, 藤枝 俊宣.「3Dバイオプリンティングに向けたカルボキシメチルキトサンとタンニン酸からなる自己修復性ハイドロゲルの創製」第72回高分子年次大会 (2023.5.26., 東京). 

[2] 小此木 葵衣, 藤田 創, 堀井 辰衛, 藤枝 俊宣.「導電性高分子とポリビニルアルコール複合薄膜を用いた耐水性を有する湿度センサの開発」第72回高分子年次大会 (2023.5.26., 東京). 

[3] 孫 健, 鵜澤 尊規, 伊藤 嘉浩, Tod E. Kippin, Kevin W. Plaxco, 藤枝 俊宣.「Utilizing Polyethylene glycol-based self-assembled monolayer for improved electrochemical aptamer-based sensor stability」第72回高分子年次大会 (2023.5.25., 東京). 

[4] 関田 大生, 水野 陽介, 藤田 創, 藤枝 俊宣.「フェノール性ヒドロキシ基を有する エラストマー 薄膜の作製と接着性評価」第72回高分子年次大会 (2023.5.24., 東京). 



We will open our lab to the public during the Suzukake Science Day 2023 on May 13-14.
Let's enjoy to see what's going on in the Fujie Lab!




Our research activity related to the JST FOREST Project has been featured in the School Homepage.
Please check it out!



Toshi has joined as a concurrent member of Living Systems Materialogy (LiSM) Research Group, International Research Frontiers Initiative (IRFI) in Tokyo Institute of Technology.



私達が参画する東京工業大学生命理工オープンイノベーションハブ 神経医療機器開発グループのホームページが公開されました。


Members Updated!

Welcome Ryuta Okada, Zichen Gao and Masaki Ito to our group!

News 2022


Graduation Ceremony

Daiki and Tasuku received Bachelor's Degrees, and Ayano, Kei, Marimo, Megumi and Shu received Master's Degree from TokyoTech.

Congratulations and good luck on your prestigious future!!


Award Announcement

Kon received the Encouragement Award from Tanaka Kikinzoku Memorial Foundation! Congratulations!!


New paper is out! 

Masato contirbuted the development of liquid metal-based wearable heaters and strain sensors. This work has been achieved under the collaboration with Prof. Sungjune Park in Jeonbuk National University.

Kim, S., Saito, M., Wei, Y., Bhuyan, P., Choe, M., Fujie, Y., Mondal, K., Park, S. Stretchable, Soft and Wearable Polymeric Heaters and Strain Sensors Fabricated using Liquid Metals. Sens. Actuators A Phys., 355, 114317 (2023).
(DOI: 10.1016/j.sna.2023.114317)


New paper is out! 

We contirbuted the development of a polarization-independent transmission color sheet. This work has been achieved under the collaboration with Prof. Kazuhiro Takahashi in Toyohashi University of Technology.

Tay, S-W., Watanabe, M., Endo, F., Choi, Y-J., Sawada, K., Fujie, T., Takahashi, K. Polarization-independent transmission color sheet using 2D plasmonic metasurface embedded in elastomer nanosheet. Appl. Phys. Express, in press (2023). (DOI: 10.35848/1882-0786/acc005)


New paper is out! 

Moeka (Visiting Student from Waseda University) and Tatsuhiro developed unique photo-reversible adhesives with debonding-on-demand properties. This work has been achieved under the collaboration with Prof. Toru Asahi in Waseda University and Prof. Kei Saito in Kyoto University.

Inada, M., Horii, H., Fujie, T., Nakanishi, T., Asahi, T., Saito, K. Debonding-on-demand adhesives based on photo-reversible cycloaddition reactions. Mater. Adv., in press (2023). (DOI: 10.1039/D2MA01048H)


Members Updated!

Welcome Mayuko, Keto and Yusuke to our group!


Award Announcement

Toshi received The Award of Ohsumi Life Science Research Society for Young Scientist from the Ohsumi Life Science Research Society! Congratulations!!


Special Exhibition at Miraikan「いいかげんなロボット展」

We will participate the special exhibition of soft robotics at Miraikan.

Kei and Tatsuhiro will show unique sensor using a flexible strain gauge equipped on the soft robot replicating organ "rectum". Let's join us!


Award Announcement

Masato received Poster Award in the 44th Annual Meeting of the Japanese Society for Biomaterials from the Japanese Society for Biomaterials! Congratulations!!

Conference Information

2022.11.21-22, 日本バイオマテリアル学会大会


[1] 齋藤 優人, 野本 貴大, 横式 康史, 德田 崇, 藤枝 俊宣.「メトロノミック光線力学療法に向けたフレキシブル薄膜状発光デバイスの開発」第44回日本バイオマテリアル学会大会 (2022.11.21., 東京). ハイライト講演

[2] 田熊 めぐみ, 藤田 創, 藤枝 俊宣.「脂肪組織由来幹細胞とPDMSナノ薄膜からなる細胞封入デバイスの開発と血管新生の増強効果」第44回日本バイオマテリアル学会大会 (2022.11.21., 東京). ハイライト講演

[3] 藤枝 俊宣, 今井 綾乃, 古林 捷, 高橋 俊太, 水野 陽介, 宮下 英三.「難治てんかんに向けた脳皮質電位の記録と電気刺激が可能なフレキシブル薄膜電極の開発」第44回日本バイオマテリアル学会大会 (2022.11.22., 東京).

2022.11.24-26, 第52回日本臨床神経生理学会学術大会

[1] 藤枝 俊宣.「てんかん診断治療に向けたフレキシブル薄膜電極の開発」第52回日本臨床神経生理学会学術大会 (2022.11.25., 京都).

Conference Information

2022.11.8-11, 35th International Microprocesses and Nanotechnology Conference (MNC2022)

[1] Fujie, T. Flexible and adhesive electronics for directing living body, MNC2022. (2022.11.9., Tokushima). 

[2] Horii, T., Okada, K., Fujie, T. Ultra-Thin and Conductive Films Composed of Single-Walled Carbon Nanotubes for Dielectric Elastomer Actuators, MNC2022. (2022.11.10., Tokushima). 

[3] Saito, M., Kanai, E., Fujita, H., Matsutani, N., Fujie, T. Flexible Induction Heater Based on the Polymeric Thin-film and Inkjet-Printed Au Wirings toward Local Thermotherapy, MNC2022. (2022.11.10., Tokushima). 

2022.10.3-7, The 22nd edition of the Trends in Nanotechnology International Conference (TNT2022)

[1] Fujie, T. Ultra-Flexible Electronics Interfacing Living Body, TNT2022. (2022.10.6., Tirana). 


New paper is out! 

Megumi contributed the development of an engineered basement membrane in a microfluidic blood-brain-barrier model. This work has been achieved under the collaboration with Prof. Virginia Pensabene in University of Leeds.

Mancinelli, E., Takuma, M., Fujie, T., Pensabene, V. “Recreating cellular barriers in human microphysiological systems in-vitro”, Proc. 2022 44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 3923-3926 (2022).  (DOI: 10.1109/EMBC48229.2022.9870981)

Conference Information

2022.9.20-23, 第83回応用物理学会秋季学術講演会

[1] 今井 綾乃, 古林 捷, 高橋 俊太, 水野 陽介, 宮下 英三, 藤枝 俊宣.「脳皮質電位記録と刺激のためのフレキシブル薄膜電極の開発」第83回応用物理学会秋季学術講演会 (2022.9.20., 仙台).

[2] 今井 蘭, 齋藤 優人, 藤枝 俊宣.「レーザー誘起グラフェンからなる薄膜状発熱ユニットの作製と発熱制御」第83回応用物理学会秋季学術講演会 (2022.9.20., 仙台).

[3] 齋藤 優人, 野本 貴大, 横式 康史, 徳田 崇, 藤枝 俊宣.「無線給電式薄膜状発光デバイスの開発と局所的光増感作用の検証」第83回応用物理学会秋季学術講演会 (2022.9.20., 仙台).

2022.9.20-23, 日本金属学会2022年秋期(第171回)講演大会

[1] 藤枝 俊宣.「埋め込み型発光デバイスによる光がん治療システムの開発」日本金属学会2022年秋期(第171回)講演大会 (2022.9.21., 福岡).

2022.9.5-7, 第71回高分子討論会

[1] 三田 博亮, 水野 陽介, 藤枝 俊宣.「バイオアクチュエータの開発に向けたUVレーザー加工を用いた微細溝薄膜の作製」第71回高分子討論会 (2022.9.5., 札幌).

[2] 藤枝 俊宣, 藤田 創.「生体接合型エレクトロニクスに向けたバイオセンシング素子の開発」第71回高分子討論会 (2022.9.5., 札幌).

[3] 堀井 辰衛, 岡田 慧, 藤枝 俊宣.「導電性超薄膜から成る皮膚へ貼付可能な伸縮性電極の誘電エラストマーアクチュエータへの応用」第71回高分子討論会 (2022.9.6., 札幌).



Hajime and Yosuke left our group for the next step.
Stay in touch! Good luck for your future career!!


Award Announcement

Hajime received the Ohsumi Journal Award from TokyoTech! 

This award was founded by Honorary Professor Yoshinori Ohsumi, 2016 Nobel laureate in Physiology or Medicine, for promoting students in School of Life Science and Technology. 



Award Announcement

Masato received the FSE Best Presentation Award in The 4th Event of the Young Researchers Society for Flexible and Stretchable Electronics! Congratulations!!

Conference Information

2022.7.19, 第3回iCONM学術セミナー

[1] 藤枝 俊宣.「生体貼付型エレクトロニクスの創製と医療・ヘルスケアへの展開」第3回iCONM学術セミナー (2022.7.19., オンライン).


New paper is out! 

Hajime contributed the development of the transparent, flexible, and gas-permeable temperature and humidity sensors. This work has been achieved under the collaboration with Prof. Hiroki Ota in Yokohama National University.

Isano, Y., Fujita, H., Murakami, K., Ni, S., Kurotaki, Y., Takano, T., Isoda, Y., Matsuda, R., Nakamura, F., Nishitai, Y., Ochirkhuyag, N., Inoue, K., Kawakami, H., Okubo, Y., Ueno, K., Fujie, T., Ota, H. Transparent and Breathable Ion Gel-based Sensors towards Multimodal Sensing Ability. Adv. Mater. Technol., in press (2022). (DOI: 10.1002/admt.202200209)


New paper is out! 

Tatsuhiro and Kei developed conductive, free-standing ultra-thin films as electrodes of a dielectric elastomer actuator (DEA) with skin conformability. 

Horii, T., Okada, K., Fujie, T*(Corresponding). Ultra-thin and conformable electrodes composed of single-walled carbon nanotube networks for skin-contact dielectric elastomer actuators. Adv. Electron. Mater., in press (2022). (DOI: 10.1002/aelm.202200165)


New paper is out! 

Tatsuhiro introduced design principle of flexible devices from mechanical viewpoints including our recent achievements. 

This work has been achieved under the collaboration with Dr. Kenjiro Fukuda in RIKEN.

Horii, T., Fujie, T., Fukuda, K. Flexible Thin-Film Device for Powering Soft Robots, J. Robot. Mechatron, 34(2), 227-230 (2022). (DOI: 10.20965/jrm.2022.p0227)


Members Updated!

Welcome Nanami Zushi to our group!