Toshinori Fujie Research Group
Laboratory for Integrated NanoBioElectronics
Nexus of Nano, Bio and Electronics for Human Healthcare
Welcome to Fujie Lab @ Tokyo Institute of Technology!
We are envisaging the development of innovative therapeutics and diagnostics.
大学院生募集中
藤枝研では大学院生を募集しています。藤枝（t_fujie＠bio.titech.ac.jp）までお気軽にお問い合わせ下さい。
キーワード：ナノバイオマテリアル，組織工学，細胞治療，ウェアラブル・インプランタブルデバイス
大学院入学案内
https://www.titech.ac.jp/graduate_school/admissions/
https://www.titech.ac.jp/contact/
https://educ.titech.ac.jp/bio/news/2019_05/057409.html
News
News 2024
Conference Information
2024.4.25, 2024 MRS Spring Meetings & Exhibit.
https://www.mrs.org/meetings-events/spring-meetings-exhibits/2024-mrs-spring-meeting
[1] Fujie, T. Tissue-Interfaced Electronics for Directing Biological Functions, 2024 MRS Spring Meetings & Exhibit. (2024.4.25., Seattle).
2024.4.5, 日本表面真空学会・2024年度関東支部講演大会
https://www.jvss.jp/chapter/kanto/files/2024_kanto/index.html
[1] 藤枝 俊宣.「バイオインテグレーションに向けた薄膜エレクトロニクスの開発」日本表面真空学会・2024年度関東支部講演大会 (2024.4.5., 東京).
2024.4.1
Members Updated!
Welcome Mahiro Suzuki to our group! Tatsuhiro has been promoted to be a Specially Appointed Assistant Professor!
News 2023
2024.3.28
Award Announcement
Yusuke received the Best Bachelor's Thesis Presentation Award from the Department of Life Science and Technology! Congratulations!!
2024.3.26
Graduation Ceremony
Kento, Mayuko and Yusuke received Bachelor's Degrees, and Aoi, Hiroaki, Nanami and Ran received Master's Degree from TokyoTech.
Congratulations and good luck on your prestigious future!!
2024.3.22
Award Announcement
Aoi received the Best Master's Thesis Presentation Award from the Course of Human Centered Science and Biomedical Engineering! Congratulations!!
2024.3.15
New paper is out!
Toshi contributed to the development of an water-reisitant bioelectrode for ECG measurement. This work has been achieved under the collaboration with Prof. Shnjiro Umezu in Waseda University.
Song, K., Hirose, K., Niitsu, K., Sui, T., Kojima, H., Fujie, T*(Corresponding), Umezu, S*. A combination of logical judging circuit and water-resistant ultrathin film PEDOT: PSS electrode for noninvasive ECG measurement. Discover Nano, 19, 45 (2024). (DOI: 10.1186/s11671-024-03988-9)
https://link.springer.com/article/10.1186/s11671-024-03988-9
2024.3.4
Award Announcement
Mayuko received the Takamiya Award from the School of Life Science and Technology! Congratulations!!
2024.3.1
New paper is out!
Nanami and Megumi contributed to the development of an endothelial barrier-on-chip using porous polymeric nanofilms. This work has been achieved under the collaboration with Prof. Virginia Pensabene and Dr. Elena Mancinelli in University of Leeds.
Mancinelli, E., Zushi, N., Takuma, M., Chau, C., Parpas, G., Fujie, T., Pensabene. V. Porous polymeric nanofilms for recreating the basement membrane in an endothelial barrier-on-chip. ACS Appl. Mater. Interfaces, in press (2024). (DOI: 10.1021/acsami.3c16134)
2024.2.20
New paper is out!
Kei, Tatsuhiro, Kon developed ultra-flexible capacitive stratin sensor for wireless body sensing. This work has been achieved under the collaboration with Prof. Naoki Hosoya in Shibaura Institute of Technology and Prof. Shingo Maeda in TokyoTech.
Okada, K., Horii, T., Yamaguchi, Y., Son, K., Hosoya, N., Maeda, S., Fujie, T*(Corresponding). Ultra-Conformable Capacitive Strain Sensor Utilizing Network Structure of Single-Walled Carbon Nanotubes for Wireless Body Sensing. ACS Appl. Mater. Interfaces, in press (2024). (DOI: 10.1021/acsami.3c19320)
2024.2.9
New paper is out!
Hiroaki and Yosuke developed biohybrid actuators with life-like twisting movements. This work has been achieved under the collaboration with Prof. Hiroto Tanaka in TokyoTech.
Mita, H., Mizuno, Y., Tanaka, H., Fujie, T*(Corresponding). UV Laser-Processed Microstructure for Building Biohybrid Actuators with Anisotropic Movement. Biofabrication, in press (2024). (DOI: 10.1088/1758-5090/ad2080)
https://iopscience.iop.org/article/10.1088/1758-5090/ad2080
https://www.titech.ac.jp/news/2024/068468
[Media Distribution]
2024.1.31
Deligates from the U.S. Senate and the U.S. Embasy Tokyo
We warmly welcome the deligates from the U.S. Senate and the U.S. Embassy Tokyo.
Conference Information
2024.1.22, 新化学技術推進協会 ライフサイエンス技術部会 脳科学分科会講演会「神経計測」
[1] 藤枝 俊宣.「薄膜エレクトロニクスに基づく神経計測・制御技術の開発」新化学技術推進協会 ライフサイエンス技術部会 脳科学分科会講演会「神経計測」 (2024.1.22., 東京).
Conference Information
2023.12.19, 接着学会 次世代接着材料研究会 PartⅨ第7回例会
https://www.adhesion.or.jp/event/news/news_detail_1123.html
[1] 藤枝 俊宣.「生体貼付型デバイスの開発と医療・ヘルスケア分野への応用」接着学会 次世代接着材料研究会 PartⅨ第7回例会 (2023.12.19., オンライン).
2023.12.6, IEEE NANOMED 2023
https://ieee-nanomed.org/2023/
[1] Fujie, T. Directed Biological Function with Ultra-Conformable Electronics, IEEE NANOMED 2023. (2023.12.6., Okinawa).
2023.11.21
Award Announcement
Hiroaki received the FSE Best Oral Presentation Award in The 6th Event of the Young Researchers Society for Flexible and Stretchable Electronics! Congratulations!!
2023.11.10
Award Announcement
Toshi received the Best Review Paper Award from Smart Processing Society for Materials, Environment & Energy. Congratulations!
https://sps-mste.jp/smartprocess.or.jp/contents/award/index.html
Webinar Information
2023.11.8, Recent Advances in Ultra-thin Electronics by Advanced Electronic Materials, Wiley
Join our free virtual event about recent advances in ultra-thin electronics, soft electronic applications and their development. You can register from the following link:
https://register.gotowebinar.com/register/4059953716915039839?source=SpeakersShare
Overview
Low thickness is one key approach to obtaining conformable and soft electronics. This rapidly evolving research field focuses on the integration of electronic components and devices onto non-rigid, non-planar, complex 3D surfaces and objects. The technology is poised to bridge the gap between biology and electronics, particularly in the development of unperceivable electronic systems integrated with the human body, with conformal features.
Hear from experts in the field:
• George Malliaras: Multishank Thin-Film Neural Probes and Implantation System for High-Resolution Neural Recording Applications
• Barbara Stadlober: How to combine ultrathin ferroelectric sensors and organic transistors for high-resolution biosignal monitoring and energy harvesting
• Toshinori Fujie: Tissue-lnterfaced Electronics with Nanosheet Technology
• Virgilio Mattoli: Ultrathin Conformable Tattoos for On-Skin Sensing and Tactile Stimulation
Conference Information
2023.11.6-7, 第45回日本バイオマテリアル学会大会
[1] 藤枝 俊宣.「薄膜エレクトロニクスによるバイオインテグレーション」第45回日本バイオマテリアル学会大会 (2023.11.7., 神戸).
[2] 圖師 菜々美，田熊 めぐみ, Yumeng Wu, 遠藤 貴南, 粂 昭苑, 白木 伸明, 藤枝 俊宣.「多孔質高分子ナノシートの積層によるタンパク質透過性の制御」第45回日本バイオマテリアル学会大会 (2023.11.6., 神戸).
[3] 三田 博亮，水野 陽介, 田中 博人, 藤枝 俊宣.「筋細胞からなる薄膜状バイオアクチュエータの開発と微細溝構造による収縮挙動の制御」第45回日本バイオマテリアル学会大会 (2023.11.6.神戸).
[4] 齋藤 優人，野本 貴大，横式 康史，德田 崇，藤枝 俊宣.「異なる発色光のLED搭載デバイスによる局所的な光増感作用の制御」第45回日本バイオマテリアル学会大会 (2023.11.6, 神戸).
[5] 堀井 辰衛, 山下 佳威, Marimo Ito, 岡田 慧, 藤枝 俊宣. 「繊維化ネットワーク構造を有する単層カーボンナノチューブからなる超薄膜生体電極の作製と水蒸気透過性の評価」第45回日本バイオマテリアル学会大会 (2023.11.6, 神戸). ハイライト講演に選出されました！
2023.11.2, FSE若手6th event
https://fsejp.weebly.com/6th-event-nov-2-2023.html
[1] 三田 博亮，水野 陽介, 田中 博人, 藤枝 俊宣.「Development of thin-film biohybrid actuators with muscular cells and UV laser-processed microstructure for anisotropic movement」FSE若手6th event (2023.11.2., オンライン).
[2] 小此木 葵衣, 藤田 創, 堀井 辰衛, 藤枝 俊宣.「Development of a Thin-Film Flexible Humidity Sensor Composed of Conductive Polymer and Polyvinyl Alcohol」FSE若手6th event (2023.11.2., オンライン).
2023.11.19-21, 第56回日本てんかん学会学術集会
https://www.c-linkage.co.jp/jes56/
[1] 藤枝 俊宣.「難治てんかん診断治療に向けたフレキシブル薄膜電極の開発」第56回日本てんかん学会学術集会 (2023.10.20, 東京).
2023.9.28
Members Updated!
Welcome Eduardus Ariasena to our group!
2023.9.22
Graduation Ceremony
Kon received PhD Degree from TokyoTech. He is the first PhD degree holder from the Fujie Group! Congratulations and good luck on your prestigious future!!
2023.9.15
New paper is out!
Ayano developed flexible thin-film neural elkectrodes for for diagnosis and treatment of epilepsy. This work has been achieved under the collaboration with Prof. Eizo Miyashita in TokyoTech and Profs. Masaki Sonoda and Tomoyuki Miyazaki in Yokohama City University.
Imai, A., Takahashi, S., Furubayashi, S., Mizuno, Y., Sonoda, M., Miyazaki, T., Miyashita, E.*, Fujie, T*(Corresponding). Flexible thin-film neural electrodes with improved conformability for ECoG measurements and electrical stimulation. Adv. Mater. Technol., in press (2023). (DOI: 10.1002/admt.202300300)
https://onlinelibrary.wiley.com/doi/full/10.1002/admt.202300300
https://www.titech.ac.jp/news/2023/067460
https://www.titech.ac.jp/english/news/2023/067462
[Media Distribution]
Conference Information
2023.9.27, 第72回高分子討論会
https://main.spsj.or.jp/tohron/72tohron/
[1] 齋藤 優人, 野本 貴大, 横式 康史, 徳田 崇, 藤枝 俊宣.「局所的な光増感作用発現のための無線給電型薄膜状発光デバイスの開発」第72回高分子討論会 (2023.9.27., 香川).
2023.9.19, 第84回応用物理学会秋季学術講演会
[1] 堀井 辰衛, 山下 佳威, 岡田 慧, Marimo Ito, 藤枝 俊宣. 「単層カーボンナノチューブファイバーネットワークを利用した高い水蒸気透過率を有する伸縮性生体電極」第84回応用物理学会秋季学術講演会 (2023.9.19., 熊本).
2023.9.11, 2023電気化学秋季大会
https://confit.atlas.jp/guide/event/ecsj2023f/top?lang=ja
[1] 孫 健, 寺井 健人, Kaylyn Leung, Julian Gerson, 鵜澤 尊規, Kevin Plaxco, 藤枝 俊宣.「皮膚貼付型電気化学アプタマーセンサの開発に向けた電極表面構造の検討」2023電気化学秋季大会 (2023.9.11., 福岡).
2023.8.31
Award Announcement
Kon received the IPC2023 Young Scientist Poster Award! This award was dedicated for some excellent poster presenters aged 36 or under as of April 1, 2023. Congratulations!!
Conference Information
2023.8.4, 第11回Chem-Bio Joint Seminar2023
https://www.jsac.jp/conference/group_event/
[1] 藤枝 俊宣.「薄膜エレクトロニクスが拓く生体計測制御技術」第11回Chem-Bio Joint Seminar2023 (2023.8.4., 東京).
2023.8.3, 第46回日本神経科学大会
https://neuroscience2023.jnss.org/
[1] 藤枝 俊宣.「脳神経機能の操作に向けた薄膜エレクトロニクスの開発」第46回日本神経科学大会 (2023.8.3., 仙台).
2023.7.20, The 13th SPSJ International Polymer Conference
https://main.spsj.or.jp/ipc/2023/index.html
[1] Son, K., Uzawa, T., Ito, Y., Kippin, T., Plaxco, K. W., Fujie, T. Real time measurement of in brain dopamine using electrochemical aptamer-based (E-AB) biosensors. The 13th SPSJ International Polymer Conference (2023.7.20., Sapporo).
2023.7.25
Visiting Researcher fromUK
We warmly welcome Prof. Virginia Pensabene & Ms. Elena Mancinelli from The University of Leeds! We will conduct the collaboration research in organ-on-a-chip for next weeks.
2023.6.21
Award Announcement
Tasuku received the Best Poster Award in the Young Researchers Symposium of The Adeshion Society of Japan（日本接着学会 若手交流シンポジウム 2023）! Congratulations!!
2023.5.31
New paper is out!
Kon investigated the effect of oligoethylene glycol-based self-assembled monolayers on electrochemical aptamer-based sensor. This work has been achieved under the collaboration with Prof. Kevin Plaxco in UCSB and Dr. Takanori Uzawa in RIKEN.
Son, K., Uzawa, T., Ito, Y., Kippin, T., Plaxco, K. W.*, Fujie, T*(Corresponding). Survey of oligoethylene glycol-based self-assembled monolayers on electrochemical aptamer-based sensor in biological fluids. Biochem. Biophys. Res. Commun., 668, 1-7 (2023). (DOI: 10.1016/j.bbrc.2023.05.032)
https://www.sciencedirect.com/science/article/abs/pii/S0006291X23005946
2023.5.19
Award Announcement
Tatsuhiro received the FSE Best Poster Award in The 5th Event of the Young Researchers Society for Flexible and Stretchable Electronics! Congratulations!!
Conference Information
2023.6.21, 日本接着学会 若手交流シンポジウム2023
https://www.adhesion.or.jp/event/news/news_detail_1021.html
[1] 藤枝 俊宣.「エレクトロニクスの薄膜化により創発される医療・ヘルスケア技術」日本接着学会 若手交流シンポジウム2023 (2023.6.21, 東京).
[2] 山田 佑, 水野 陽介, 藤枝 俊宣.「3Dバイオプリンティングに向けたカルボキシメチルキトサンとタンニン酸からなる自己修復性ハイドロゲルの作製」日本接着学会 若手交流シンポジウム2023 (2023.6.21, 東京).
[3] 関田 大生, 水野 陽介, 藤田 創, 藤枝 俊宣.「ピロガロール基を有するエラストマー薄膜の作製と接着性評価」日本接着学会 若手交流シンポジウム2023 (2023.6.21, 東京).
2023.6.5-8 Biosensors 2023
https://www.elsevier.com/events/conferences/world-congress-on-biosensors
[1] Son, K., Uzawa, T., Ito, Y., Kippin, T., Plaxco, K. W., Fujie, T. Real-time monitoring of brain dopamine levels using electrochemical aptamer-based (E-AB) sensors. Biosensors 2023 (2023.6.5., Busan).
2023.5.24-26, 第72回高分子年次大会
https://main.spsj.or.jp/nenkai/72nenkai/
[1] 山田 佑, 水野 陽介, 藤枝 俊宣.「3Dバイオプリンティングに向けたカルボキシメチルキトサンとタンニン酸からなる自己修復性ハイドロゲルの創製」第72回高分子年次大会 (2023.5.26., 東京).
[2] 小此木 葵衣, 藤田 創, 堀井 辰衛, 藤枝 俊宣.「導電性高分子とポリビニルアルコール複合薄膜を用いた耐水性を有する湿度センサの開発」第72回高分子年次大会 (2023.5.26., 東京).
[3] 孫 健, 鵜澤 尊規, 伊藤 嘉浩, Tod E. Kippin, Kevin W. Plaxco, 藤枝 俊宣.「Utilizing Polyethylene glycol-based self-assembled monolayer for improved electrochemical aptamer-based sensor stability」第72回高分子年次大会 (2023.5.25., 東京).
[4] 関田 大生, 水野 陽介, 藤田 創, 藤枝 俊宣.「フェノール性ヒドロキシ基を有する エラストマー 薄膜の作製と接着性評価」第72回高分子年次大会 (2023.5.24., 東京).
2023.5.10
Announcement
We will open our lab to the public during the Suzukake Science Day 2023 on May 13-14.
Let's enjoy to see what's going on in the Fujie Lab!
5月13日－14日開催の「すずかけサイエンスデイ2023」で研究室公開をします。
この機会に藤枝研の最新テクノロジーを御覧ください。
多くの方にお立ち寄り頂きましてありがとうございました！
https://www.titech.ac.jp/event/2023/066545
2023.5.9
Announcement
Our research activity related to the JST FOREST Project has been featured in the School Homepage.
Please check it out!
https://educ.titech.ac.jp/bio/news/2023_05/064171.html
2023.4.6
Announcement
Toshi has joined as a concurrent member of Living Systems Materialogy (LiSM) Research Group, International Research Frontiers Initiative (IRFI) in Tokyo Institute of Technology.
2023.4.3
Announcement
私達が参画する東京工業大学生命理工オープンイノベーションハブ 神経医療機器開発グループのホームページが公開されました。
医理工・産官学連携の体制で革新的な神経医療機器の開発を目指します。
2023.4.1
Members Updated!
Welcome Ryuta Okada, Zichen Gao and Masaki Ito to our group!