Publications

Wend K, Zorrilla L, Freimoser FM, and Gallet A (2024). Microbial pesticides – challenges and future perspectives for testing and safety assessment with respect to human health. Environ Health. 23(1): 49. doi: 10.1186/s12940-024-01090-2.

Freimoser FM, Mahler M, McCullough M, Brachmann AO, Nägeli L, Hilber-Bodmer M, Piel J, Hoffmann SA, and Cai Y (2024). Heterologous pulcherrimin production in Saccharomyces cerevisiae confers inhibitory activity on Botrytis conidiation. FEMS Yeast Research. 24: foad053. doi: 10.1093/femsyr/foad053.

Rueda-Mejia MP, Bühlmann A, Ortiz-Merino RA, Lutz S, Ahrens CH, Künzler M, and Freimoser FM (2023). Pantothenate auxotrophy in a naturally occurring biocontrol yeast. Applied and Environmental Microbiology. doi: 10.1128/aem.00884-23.

Nägeli L, Schuler M, Segessemann T, Frei D, Frey JE, Wolfe KH, Ahrens CH, and Freimoser FM (2023). Genome sequence data of the strongly antagonistic yeast Pichia kluyveri isolate APC 11.10 B as a foundation for analysing biocontrol mechanisms. Data in Brief. 49: 109394. doi: 10.1016/j.dib.2023.109394.

Magoye E, Nägeli L, Bühlmann A, Hilber-Bodmer M, Keller P, Mühlethaler K, Riat A, Schrenzel J, and Freimoser FM (2023). Clinical Aureobasidium isolates are more fungicide sensitive than many agricultural isolates. Microbiology Spectrum. doi: 10.1128/spectrum.05299-22.

Rueda-Mejia MP, Nägeli L, Lutz S, Ortiz-Merino RA, Frei D, Frey JE, Wolfe KH, Ahrens CH, and Freimoser FM (2022). Genome sequence data of the antagonistic soil-borne yeast Cyberlindnera sargentensis (SHA 17.2). Data in Brief 40: 107799. doi: 10.1016/j.dib.2022.107799.

Bühlmann A, Kammerecker S, Müller L, Hilber-Bodmer M, Perren S, and Freimoser FM (2021). Stability of dry and liquid Metschnikowia pulcherrima formulations for biocontrol applications against apple postharvest diseases. Horticulturae 7: 459.

Collatz J, Hinz HL, Kaser JM, and Freimoser, FM (2021). Chapter 6: Benefits and risks of biological control. In: Mason P.G. Biological control: global impacts, challenges and future directions of pest management. CSIRO Publishing; 2021. 644 p.

Rueda-Mejia MP, Nägeli L, Lutz S, Hayes RD, Varadarajan AR, Grigoriev IV, Ahrens CH, and Freimoser FM (2021). Genome, transcriptome and secretome analyses of the antagonistic, yeast-like fungus Aureobasidium pullulans to identify potential biocontrol genes. Microb Cell 2021, 8, 184–202, doi:10/gmkvdw.

Magoye E, Hilber-Bodmer M, Pfister M, and Freimoser FM (2020). Unconventional yeasts are tolerant to common antifungals, and Aureobasidium pullulans has low baseline sensitivity to captan, cyprodinil, and difenoconazole. Antibiotics 9(9): 602. doi: 10.3390/antibiotics9090602.

Lutz S. Thuerig B, Oberhaensli T, Mayerhofer J, Fuchs JG, Widmer F, Freimoser FM, Ahrens CH (2020). Harnessing the microbiomes of suppressive composts for plant protection: from metagenomes to beneficial microorganisms and reliable diagnostics. Front Microbiol. DOI: 10.3389/fmicb.2020.01810.

 Magoye E, Pfister M, Hilber-Bodmer M, and Freimoser FM (2020). Competition assays to quantify the effect of biocontrol yeasts against plant pathogenic fungi on fruits. Bio-protocol 10(3): e3518. DOI: 10.21769/BioProtoc.3518. 

Freimoser FM, Rueda-Mejia MP, Tilocca B, and Migheli Q (2019). Biocontrol yeasts: mechanisms and applications. World J Microbiol Biotechnol 35(10): 154. 31576429 (DOI: 10.1007/s11274-019-2728-4)

Gore-Lloyd D, Sumann I, Brachmann AO, Schneeberger K, Ortiz-Merino RA, Moreno-Beltran M, Schlaefli M, Kirner P, Santos Kron A, Rueda-Mejia MP, Somerville V, Wolfe KH, Piel J, Ahrens CH, Henk D, Freimoser FM* (2019). Snf2 controls pulcherriminic acid biosynthesis and antifungal activity of the biocontrol yeast Metschnikowia pulcherrima. Mol Microbiol 112(1):317-332 (DOI. 10.1111/mmi.14272). (*corresponding author)

Gross S, Kunz L, Müller DC, Santos Kron A, *Freimoser FM (2018). Characterisation of antagonistic yeasts for biocontrol applications on apples or in soil by quantitative analyses of synthetic yeast communities. Yeast (DOI: 10.1002/yea.3321). (*corresponding author)

Drissner D, *Freimoser FM (2017): MALDI-TOF mass spectroscopy of yeasts and filamentous fungi for research and diagnostics in the agricultural value chain. Chem Biol Technol Agricult 4: 13 (DOI: 10.1186/s40538-017-0095-7). (*corresponding author)

Hilber-Bodmer M, Schmid M, Ahrens CH, *Freimoser, FM (2017): Competition assays and physiological experiments of soil and phyllosphere yeasts identify Candida subhashii as a novel antagonist of filamentous fungi. BMC Microbiol 17, 4 (DOI: 10.1186/s12866-016-0908-z). (*corresponding author)

*Freimoser FM, *Pelludat C, *Remus-Emsermann MNP (2016): Tritagonist as a new term for uncharacterised microorganisms in environmental systems. ISME J 10(1): 1-3 (DOI: 10.1038/ismej.2015.92). (*all authors contributed equally)

*Freimoser FM, Hilber-Bodmer M, Brunisholz R, Drissner D (2016): Direct identification of Monilinia brown rot fungi on infected fruits by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. Chem Biol Technol Agricult 3: 7 (DOI: 10.1186/s40538-016-0058-4). (*corresponding author)

Luginbuehl E, Kunz S, Wentzinger L, Freimoser F, Seebeck T (2011): The exopolyphosphatase TbrPPX1 of Trypanosoma brucei. BMC Microbiol 11, 4 (DOI:doi:10.1186/1471-2180-11-4).

*Hürlimann HC, *Pinson B, Stadler-Waibel M, Zeeman SC, Freimoser FM (2009): The SPX domain of the yeast low-affinity phosphate transporter Pho90 regulates transport activity. EMBO reports 10, 1003-1008 (DOI:10.1038/embor.2009.105). (*joint first authors)

Zaborske JM, Narasimhan J, Jiang L, Wek SA, Dittmar KA, Freimoser F, Pan T, Wek RC (2009): Genome-wide analysis of tRNA charging and activation of the eIF2 kinase Gcn2p. J Biol Chem 284, 25254-25267 (DOI: 10.1074/jbc.M109.000877).

Holbein S, Wengi A, Decourty L, Freimoser FM, Jacquier A, Dichtl B (2009): Cordycepin interferes with 3’ end formation in yeast independently of its potential to terminate RNA chain elongation. RNA 15, 837-849 (DOI: 10.1261/rna.1458909).

*Holbein S, *Freimoser FM, Werner TP, Wengi A, Dichtl B (2008): Cordycepin-hypersensitive growth links elevated polyphosphate levels to inhibition of poly(A) polymerase in Saccharomyces cerevisiae.  Nucleic Acids Res 36, 353-363 (DOI:10.1093/nar/gkm990). (*joint first authors) 

Denton MD, Veneklaas EJ, Freimoser FM, Lambers H (2007): Banksia species (Proteaceae) from severely phosphorus-impoverished soils exhibit extreme efficiency in the use and re-mobilization of phosphorus. Plant, Cell Environ 30, 1557–1565 (DOI: 10.1111/j.1365-3040.2007.01733.x).

Werner TP, Amrhein N, Freimoser FM (2007): Inorganic polyphosphate occurs in the cell wall of Chlamydomonas reinhardtii and accumulates during cytokinesis. BMC Plant Biol 7, 51 (DOI:10.1186/1471-2229-7-51).

Hürlimann HC, Stadler-Waibel M, Werner TP, Freimoser FM (2007): Pho91 is a vacuolar phosphate transporter that regulates phosphate and polyphosphate metabolism in Saccharomyces cerevisiae. Mol Biol Cell 18, 4438-4445 (DOI: 10.1091/mbc.E07-05-0457).

Werner TP, Amrhein N, Freimoser FM (2007): Specific localization of inorganic polyphosphate (poly P) in fungal cell walls by selective extraction and immunohistochemistry. Fungal Genet Biol 44, 845-852 (DOI:10.1016/j.fgb.2007.01.008).

*Freimoser FM, Hürlimann HC, Jakob JA, Werner TP, Amrhein N (2006): Systematic screening of polyphosphate (poly P) levels in yeast mutant cells reveals strong interdependence with primary metabolism. Genome Biol 7, R109 (DOI: 10.1186/gb-2006-7-11-r109). (*corresponding author)

Werner TP, Amrhein N, Freimoser, FM (2005): Novel method for the quantification of inorganic polyphosphate (iPoP) in Saccharomyces cerevisiae shows dependence of iPoP content on the growth phase. Arch Microbiol 184, 129-136 (DOI: 10.1007/s00203-005-0031-2).

Freimoser FM, Hu G, St. Leger R (2005)J:  Variation in gene expression patterns as the insect pathogen Metarhizium anisopliae adapts to different host cuticles or nutrient deprivation. Microbiology 151, 361-371 (DOI: 10.1099/mic.0.27560-0).

Freimoser FM, Screen S, Hu G, St. Leger RJ (2003): EST analysis of genes expressed by the zygomycete pathogen Conidiobolus coronatus during optimized secretion of proteinases. Microbiology 149, 1893-1900 (DOI: 10.1099/mic.0.26252-0).

Freimoser FM, Grundschober A, Tuor U, Aebi M (2003): Regulation of hyphal growth and sporulation of the insect pathogenic fungus Entomophthora thripidum in vitro. FEMS Microbiol Lett 222, 281-287 (DOI: 10.1016/S0378-1097(03)00315-X).

Freimoser FM, Screen S, Bagga S, Hu G, St. Leger RJ (2003): Expressed sequence tag (EST) analysis of two species of Metarhizium anisopliae reveals a plethora of secreted proteins with potential activity in insect hosts. Microbiology 149, 239-247 (DOI: 10.1099/mic.0.25761-0).

Freimoser FM, Jensen AB, Tuor U, Aebi M, Eilenberg J (2001): Isolation and in vitro cultivation of the aphid pathogenic fungus Entomophthora planchoniana. Can J Microbiol 47, 1082-1087.

Grundschober A, Freimoser FM, Tuor U, Aebi M (2001): In vitro spore formation and completion of the asexual life cycle of Neozygites parvispora, an obligate biotrophic pathogen of thrips. Microbiol Res 156, 247-257.

*Freimoser FM, *Grundschober A, Aebi M, Tuor U (2000): In vitro cultivation of the entomopathogenic fungus Entomophthora thripidum: isolation, growth requirements and sporulation. Mycologia 92, 208-215. (*both authors contributed equally)

Freimoser FM, Jakob CA, Aebi M, Tuor U (1999): The MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay is a fast and reliable method for colorimetric determination of fungal cell densities. Appl Environm Microbiol 65, 3727-3729.