The RNA World and the Early Evolution of the Translational Machinery
Recently, RNA gained renewed attention with CRISPR/Cas9 gene editing and mRNA vaccines. Insights into ribosome structure have fueled interest in its early evolution, especialy the discovery of a pseudo-symmetrical region at its core, suggesting a proto-ribosome that may have existed in early life. Recent studies have aimed to confirm and characterize this ancient molecular fossil within the modern ribosome.
On Protein Design and Evolution: Applying Evolutionary Insights to Protein Engineering
Proteins are highly versatile macromolecules involved in key biological processes such as metabolism, transport, and gene regulation. Their functional diversity arises from the evolution of protein folds, with many fragments repurposed as building blocks for new structures. This talk wil explore how studying protein sequence duplication and fusion sheds light on protein diversification. It wil also discuss how these insights help test evolutionary hypotheses and design novel proteins, showing that complex structures can be created from simpler components.
Evolutionary Trends in the Kingdom Fungi
The Kingdom Fungi, with an estimated 1.2-3.8 milion species, plays vital roles in ecosystems as decomposers and symbionts. While sharing some evolutionary trends with plants and animals, such as land colonization and multicelularity, fungi uniquely excel in organic decomposition and producing secondary metabolites. This talk explores these trends through genomic, paleontological, and ecological evidence, and highlights future research directions .
On the Origin and Early Evolution of Viruses
Exploring one of the most intriguing and fundamental questions in biology: how viruses emerged and evolved. Viruses, despite their simplicity, have played a crucial role in shaping life on Earth, influencing evolutionary processes across al domains of life. Yet, their origins remain shrouded in mystery, with ongoing debates about whether they predate or emerged alongside celular life.
Creationism and Evolution
Diverse perspectives surrounding the origins and development of life. At the heart of this ongoing dialogue lies a fundamental question: How did life, in al its complexity, come to be? While the theory of evolution, grounded in scientific inquiry, explains biological diversity through natural selection and genetic change over time, creationist views offer faith based interpretations of life's origins, often rooted in religious texts
UNLOCKING THE SECRETS OF ANTI FREEZE PROTEINS
In this talk we wil explore the fascinating and vital role of Anti Freeze Proteins (AFPs) in nature and their growing potential in biotechnology. This proteins are found in organisms that thrive in freezing environments, such as polar fish, insects, and plants. They prevent ice crystal formation, enabling survival in subzero temperatures. Currently at the Molecular Evolution and Bioinformatics (MEB lab) there is a new research line related to an AFP from the beetle Tenebrio molitor.